scholarly journals Pharmacological Activity, Pharmacokinetics, and Toxicity of Timosaponin AIII, a Natural Product Isolated From Anemarrhena asphodeloides Bunge: A Review

2020 ◽  
Vol 11 ◽  
Author(s):  
Yan Lin ◽  
Wai-Rong Zhao ◽  
Wen-Ting Shi ◽  
Jing Zhang ◽  
Kai-Yu Zhang ◽  
...  
Keyword(s):  
Natural Product ◽  
Pharmacological Activity ◽  
Anemarrhena Asphodeloides ◽  
Timosaponin Aiii

ChemInform Abstract: Convenient Synthesis of Wogonin, a Flavonoid Natural Product with Extensive Pharmacological Activity.

ChemInform ◽  
2009 ◽  
Vol 40 (49) ◽  
Author(s):  
Zhi-Yu Li ◽  
Xin Cao ◽  
Xin Wang ◽  
Qing-Long Guo ◽  
Qi-Dong You
Keyword(s):  
Natural Product ◽  
Pharmacological Activity ◽  
Convenient Synthesis

Convenient Synthesis of Wogonin, A Flavonoid Natural Product with Extensive Pharmacological Activity

2009 ◽  
Vol 41 (4) ◽  
pp. 327-330 ◽  
Author(s):  
Zhi-Yu Li ◽  
Xin Cao ◽  
Xin Wang ◽  
Qing-Long Guo ◽  
Qi-Dong You
Keyword(s):  
Natural Product ◽  
Pharmacological Activity ◽  
Convenient Synthesis

scholarly journals Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity

2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
K. N. Venugopala ◽  
V. Rashmi ◽  
B. Odhav
Keyword(s):  
Natural Product ◽  
Pharmacological Activity ◽  
Dietary Exposure ◽  
Herbal Remedies ◽  
Pharmacological Properties ◽  
Lead Compounds ◽  
Natural Coumarin ◽  
Low Toxicity ◽  
Anti Inflammatory

Coumarin (2H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral, anticancer, antihypertensive, antitubercular, anticonvulsant, antiadipogenic, antihyperglycemic, antioxidant, and neuroprotective properties. Dietary exposure to benzopyrones is significant as these compounds are found in vegetables, fruits, seeds, nuts, coffee, tea, and wine. In view of the established low toxicity, relative cheapness, presence in the diet, and occurrence in various herbal remedies of coumarins, it appears prudent to evaluate their properties and applications further.

Timosaponin AIII: A novel potential anti-tumor compound from Anemarrhena asphodeloides

Steroids ◽  
2018 ◽  
Vol 140 ◽  
pp. 125-130 ◽  
Author(s):  
Feng-Ying Han ◽  
Xiao-Yu Song ◽  
Jing-Jie Chen ◽  
Guo-Dong Yao ◽  
Shao-Jiang Song
Keyword(s):  
Anemarrhena Asphodeloides ◽  
Timosaponin Aiii

Moringa oleifera: A Review on Morphological, Phytochemical and Pharmacological Aspects

2017 ◽  
Vol 8 (02) ◽  
Author(s):  
Sharma Garima ◽  
Payal Pratibha ◽  
Sharma Neelu ◽  
Sharma Mahesh C.
Keyword(s):  
Natural Product ◽  
Pharmacological Activity ◽  
Moringa Oleifera ◽  
Literature Survey ◽  
Cholesterol Lowering ◽  
Ethanolic Extracts

Moringa oleifera is one of the best known, most widely distributed and naturalized species of a monogeneric family Moringaceae. Various parts of this plant such as the leaves, roots, seeds, barks, fruits etc. have been found to be immense important because of their pharmaceutical and medicinal applications such as antipyretic, antiepileptic, diuretic, cholesterol lowering, cardiac and circulatory stimulating activities. Various compounds isolated from this plant are being employed for the treatment of different ailments in the indigenous system of medicine. A thorough literature survey reveals that the aqueous, methanolic and ethanolic extracts of roots and barks were found to be effective in preventing various diseases as well as infections. These pharmaceutical and medicinal applications have made their study considerably important in the field of natural product and have prompted the research towards the isolation of such compounds with enhanced pharmacological activity.

scholarly journals Anemarrhena asphodeloides Bunge and its constituent timosaponin‐ AIII induce cell cycle arrest and apoptosis in pancreatic cancer cells

FEBS Open Bio ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. 1155-1166 ◽  
Author(s):  
Catherine B. MarElia ◽  
Arielle E. Sharp ◽  
Tiffany A. Shemwell ◽  
Y. Clare Zhang ◽  
Brant R. Burkhardt
Keyword(s):  
Cell Cycle ◽  
Pancreatic Cancer ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Induce Cell Cycle Arrest ◽  
Cycle Arrest ◽  
Pancreatic Cancer Cells ◽  
Anemarrhena Asphodeloides ◽  
Timosaponin Aiii

Synthetic studies toward inducamide C

2021 ◽  
Author(s):  
Ardalan A. Nabi ◽  
Lydia M. Scott ◽  
Daniel P. Furkert ◽  
Jonathan Sperry
Keyword(s):  
Natural Product ◽  
Structural Revision ◽  
Synthetic Studies

The rare benzoxazepine ring in the alkaloid inducamide C is unstable and prone to rearrangement, indicating that structural revision of the natural product may be necessary.

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