scholarly journals The Immune-Modulator Pidotimod Affects the Metabolic Profile of Exhaled Breath Condensate in Bronchiectatic Patients: A Metabolomics Pilot Study

2019 ◽  
Vol 10 ◽  
Author(s):  
Maria D’Amato ◽  
Debora Paris ◽  
Antonio Molino ◽  
Paola Cuomo ◽  
Andrea Fulgione ◽  
...  
Keyword(s):  
Pilot Study ◽  
Metabolic Profile ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Immune Modulator ◽  
Breath Condensate

scholarly journals Exhaled Breath Condensate: Pilot Study of the Method and Initial Experience in Healthy Subjects

2018 ◽  
Vol 61 (1) ◽  
pp. 8-16
Author(s):  
Eva Peterová ◽  
Jaroslav Chládek ◽  
Darina Kohoutová ◽  
Veronika Knoblochová ◽  
Paula Morávková ◽  
...  
Keyword(s):  
Pilot Study ◽  
Healthy Volunteers ◽  
Coefficient Of Variation ◽  
Healthy Subjects ◽  
Lung Diseases ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Initial Experience ◽  
Major Disadvantage ◽  
Breath Condensate

Analysis of Exhaled breath condensate (EBC) is a re-discovered approach to monitoring the course of the disease and reduce invasive methods of patient investigation. However, the major disadvantage and shortcoming of the EBC is lack of reliable and reproducible standardization of the method. Despite many articles published on EBC, until now there is no clear consensus on whether the analysis of EBC can provide a clue to diagnosis of the diseases. The purpose of this paper is to investigate our own method, to search for possible standardization and to obtain our own initial experience. Thirty healthy volunteers provided the EBC, in which we monitored the density, pH, protein, chloride and urea concentration. Our results show that EBC pH is influenced by smoking, and urea concentrations are affected by the gender of subjects. Age of subjects does not play a role. The smallest coefficient of variation between individual volunteers is for density determination. Current limitations of EBC measurements are the low concentration of many biomarkers. Standardization needs to be specific for each individual biomarker, with focusing on optimal condensate collection. EBC analysis has a potential become diagnostic test, not only for lung diseases.

Feasibility of Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics: A Pilot Study

2016 ◽  
Vol 16 (2) ◽  
pp. 550-558 ◽  
Author(s):  
Xiaoling Zang ◽  
María Eugenia Monge ◽  
Nael A. McCarty ◽  
Arlene A. Stecenko ◽  
Facundo M. Fernández
Keyword(s):  
Cystic Fibrosis ◽  
Pilot Study ◽  
Early Detection ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Pulmonary Exacerbations ◽  
Breath Condensate

Validity Assessment for the Results of Three Inflammatory Markers in Exhaled Breath Condensate: A Pilot Study

2009 ◽  
Vol 70 (9-10) ◽  
pp. 1387-1392 ◽  
Author(s):  
Luis M. Gonzalez-Reche ◽  
Dirk Schaefer ◽  
Thomas Göen ◽  
Thomas Kraus
Keyword(s):  
Pilot Study ◽  
Inflammatory Markers ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Validity Assessment ◽  
Breath Condensate

1H NMR To Explore the Metabolome of Exhaled Breath Condensate in α1-Antitrypsin Deficient Patients: A Pilot Study

2016 ◽  
Vol 15 (12) ◽  
pp. 4569-4578 ◽  
Author(s):  
Cristina Airoldi ◽  
Carlotta Ciaramelli ◽  
Marco Fumagalli ◽  
Rita Bussei ◽  
Valeria Mazzoni ◽  
...  
Keyword(s):  
Pilot Study ◽  
1H Nmr ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Breath Condensate
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