scholarly journals An Overview of Systematic Reviews of Chinese Herbal Medicine for Parkinson's Disease

2019 ◽  
Vol 10 ◽  
Author(s):  
Xin-Chun Jin ◽  
Li Zhang ◽  
Yong Wang ◽  
Hai-Bo Cai ◽  
Xian-Jun Bao ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Herbal Medicine ◽  
Systematic Reviews ◽  
Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Overview Of Systematic Reviews

scholarly journals Outcome Measures of Chinese Herbal Medicine for Hypertension: An Overview of Systematic Reviews

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Jie Wang ◽  
Xingjiang Xiong
Keyword(s):  
Herbal Medicine ◽  
Outcome Measures ◽  
Systematic Reviews ◽  
Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Primary Endpoints ◽  
Cochrane Database ◽  
Overview Of Systematic Reviews ◽  
Secondary Endpoints ◽  
Tcm Syndrome

Objective.The aim of this overview was to summarize the outcome measures of Chinese herbal medicine (CHM) for the treatment of hypertension based on available systematic reviews (SRs), so as to evaluate the potential benefits and advantages of CHM on hypertension.Methods.Literature searches were conducted in the Cochrane Database of Systematic Reviews, MEDLINE, and 4 databases in Chinese. SRs of CHM for hypertension were included. Two independent reviewers (J. Wang and X. J. Xiong) extracted the data.Results.10 SRs were included. 2 SRs had primary endpoints, while others focused on secondary endpoints to evaluate CHM for hypertension such as blood pressure (BP) and Traditional Chinese Medicine (TCM) syndrome. 6 SRs have reported the adverse effects, whereas the other 4 SRs have not mentioned it at all. Many CHM appeared to have significant effect on improving BP, TCM syndrome, and so on. However, most SRs failed to make a definite conclusion for the effectiveness of CHM for hypertension due to poor evidence.Conclusion.Primary endpoints have not been widely used currently. The benefits of CHM for hypertension need to be confirmed in the future with randomized controlled trials (RCTs) of more persuasive primary endpoints and high-quality SRs.

scholarly journals Chinese Herbal Medicine Paratherapy for Parkinson's Disease: A Meta-Analysis of 19 Randomized Controlled Trials

2012 ◽  
Vol 2012 ◽  
pp. 1-15 ◽  
Author(s):  
Yan Wang ◽  
Cheng-Long Xie ◽  
Lin Lu ◽  
Deng-Lei Fu ◽  
Guo-Qing Zheng
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Herbal Medicine ◽  
Adjuvant Therapy ◽  
Adverse Effects ◽  
Chinese Herbal Medicine ◽  
Conventional Treatment ◽  
Rating Scale ◽  
Meta Analysis ◽  
Chinese Herbal

Parkinson's disease (PD) is a common and debilitating neurodegenerative disorder that needs long-term levodopa administration and can result in progressive deterioration of body functions, daily activities and participation. The objective of this meta-analysis evaluates the clinical efficacy and safety of Chinese herbal medicine (CHM) as an adjunct therapy for PD patients. Methodological issues include a systematic literature search between 1950 and April 2011 to identify randomized trials involving CHM adjuvant therapy versus western conventional treatment. The outcome measures assessed were the reduction in scores of Unified Parkinson's Disease Rating Scale (UPDRS) and adverse effects. 19 trials involving 1371 participants were included in the meta-analysis. As compared to western conventional treatment, CHM adjuvant therapy resulted in greater improvement in UPDRS I, II, III, IV scores, and UPDRS I–IV total scores (P<0.001). Adverse effects were reported in 9 studies. The side effects in CHM adjuvant therapy group were generally less than or lighter than the conventional treatment group. In conclusion, CHM adjuvant therapy may potentially alleviate symptoms of PD and generally appeared to be safe and well tolerated by PD patients. However, well-designed, randomized, placebo-controlled clinical trials are still needed due to the generally low methodological quality of the included studies.

Overview of systematic reviews with meta-analyses on Chinese herbal medicine in stroke management

2019 ◽  
Vol 6 (3) ◽  
pp. 126-138
Author(s):  
Caroline Yik-fong Hung ◽  
Vincent Chi-ho Chung ◽  
Xin-yin Wu ◽  
Robin Sze-tak Ho ◽  
Endy Chun-hung Tang ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Systematic Reviews ◽  
Chinese Herbal Medicine ◽  
Stroke Management ◽  
Chinese Herbal ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses

scholarly journals Treatment of Idiopathic Parkinson's Disease with Traditional Chinese Herbal Medicine: A Randomized Placebo-Controlled Pilot Clinical Study

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Wan Fung Kum ◽  
Siva Sundara Kumar Durairajan ◽  
Zhao Xiang Bian ◽  
Sui Cheung Man ◽  
Yuen Chi Lam ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Study ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Conventional Therapy ◽  
Idiopathic Parkinson’S Disease ◽  
Chinese Herbal ◽  
Idiopathic Parkinson's Disease ◽  
Sf 36

The objective of this clinical study is to examine the effects of a Chinese herbal medicine formula (Jia Wei Liu Jun Zi Tang: JWLJZT) on motor and non-motor symptoms, and on complications of conventional therapy in idiopathic Parkinson's disease (PD), using an add-on design. Fifty-five patients with PD were randomly allocated to receive either Chinese herbal medicine or placebo for 24 weeks. Primary outcome measure was the 39-item Parkinson's Disease Questionnaire (PDQ-39). Secondary outcome measures included the Unified Parkinson's Disease Rating Scale (UPDRS), Short-Form-36 Health Survey (SF-36), Geriatric Depression Scale (GDS), home diaries, and a range of category rating scales.JWLJZTresulted in a significant improvement in the UPDRS IVC when compared with placebo at 12 weeks (P= .039) and 24 weeks (P= .034). In addition, patients in the Chinese herbal medicine group also showed significant improvement in PDQ-39 communication scores at 12 weeks (P= .024) and 24 weeks (P= .047) when compared with the placebo group. There were no significant differences between treatment and control groups for SF-36 variables, GDS score or the mean daily “on-off” time. One case of mild diarrhea was noted in the treatment group. The findings suggest thatJWLJZTcan relieve some non-motor complications of conventional therapy and improve the communication ability in patients with PD. The results of this pilot study warrant larger multi-center clinical studies to assess long-term efficacy and tolerability ofJWLJZT, and to elucidate the mechanisms by which it affects PD function.

Sign in / Sign up

Export Citation Format

Share Document