scholarly journals Bioassay-Guided Isolation of Anti-Candida Biofilm Compounds From Methanol Extracts of the Aerial Parts of Salvia officinalis (Annaba, Algeria)

2018 ◽  
Vol 9 ◽  
Author(s):  
Neila Kerkoub ◽  
Sujogya Kumar Panda ◽  
Ming-Rong Yang ◽  
Jing-Guang Lu ◽  
Zhi-Hong Jiang ◽  
...  
Keyword(s):  
Salvia Officinalis ◽  
Methanol Extracts ◽  
Aerial Parts ◽  
Candida Biofilm

scholarly journals Antibacterial and Antifungal Screening of Centaurium Pulchellum Crude Extracts and Main Secoiridoid Compounds

2010 ◽  
Vol 5 (10) ◽  
pp. 1934578X1000501 ◽  
Author(s):  
Branislav Šiler ◽  
Danijela Mišić ◽  
Jasmina Nestorović ◽  
Tijana Banjanac ◽  
Jasmina Glamočlija ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Fungal Species ◽  
Bacterial Strains ◽  
Methanol Extracts ◽  
Aerial Parts ◽  
Crude Extracts ◽  
Secoiridoid Glycosides ◽  
Antibacterial And Antifungal

The main principles of C. pulchellum (Sw.) Druce, secoiridoid glycosides, have been studied as potent bioactive compounds. Here we scored their content in extracts of ten populations of this species. Antibacterial and antifungal assays of the extracts and pure secoiridoid glycosides were performed against eight bacterial strains and five fungal species. Methanol extracts from both aerial parts and roots exhibited excellent antibacterial (0.05-0.2 mg mL−1) and very good antifungal (0.1-2 mg mL−1) activity. Pure secoiridoid glycosides isolated from these extracts demonstrated very strong antibacterial (0.01-0.04 mg mL−1) and especially antifungal (0.001-0.1 mg mL−1) activity.

Drought effects on polyphenol composition and antioxidant activities in aerial parts of Salvia officinalis L.

2010 ◽  
Vol 33 (4) ◽  
pp. 1103-1111 ◽  
Author(s):  
Iness Bettaieb ◽  
Ibtissem Hamrouni-Sellami ◽  
Soumaya Bourgou ◽  
Ferid Limam ◽  
Brahim Marzouk
Keyword(s):  
Antioxidant Activities ◽  
Salvia Officinalis ◽  
Aerial Parts ◽  
Salvia Officinalis L ◽  
Drought Effects

Chemical constituents, antimicrobial and antioxidant properties of the aerial parts of Coccinia barteri

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Ethyl Acetate ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
Antioxidant Properties ◽  
Phytochemical Analysis ◽  
Methanol Extracts ◽  
Aerial Parts ◽  
Ethyl Hexadecanoate ◽  
Bacteria And Fungi ◽  
Percentage Abundance

Phytochemical analysis of n-hexane, ethyl acetate and methanol extracts of the aerial parts of Coccinia barteri was carried out. These extracts exhibited satisfactory inhibitory activities against bacteria and fungi strains, which include; Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhii, Klebsiella pneumoniae, Candida albicans, Aspergillus niger, Penicillium notatum and Rhizopus stolonifer. Methanol extract of C. barteri possesses antioxidant activity by scavenging DPPH free radical with IC50 of 187.56 μg/mL, using DPPH antioxidant assay. GC-MS analysis of n-hexane, ethyl acetate and methanol extracts of the plant principally revealed the presence of phytol, ethyl hexadecanoate and clionasterol with their corresponding percentage abundance of 57.75%, 18.33% and 9.79%, respectively.

scholarly journals Di- and Triterpenoids Isolation and LC-MS Analysis of Salvia marashica Extracts with Bioactivity Studies

2021 ◽  
Vol 15 (6) ◽  
pp. 463-475
Author(s):  
Sibel Kıran Aydın ◽  
Abdulselam Ertaş ◽  
Mehmet Boğa ◽  
Ebru Erol ◽  
Gülbahar Özge Alim Toraman ◽  
...  
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Cation Radical ◽  
Total Phenolic ◽  
Scavenging Activity ◽  
Methanol Extracts ◽  
Aerial Parts ◽  
Ms Analysis ◽  
Abietane Diterpenes ◽  
First Time

In this study, dichloromethane, acetone, and methanol extracts of the aerial parts of the Salvia marashica plant which is an endemic species to Anatolia, were investigated. The total phenolic amounts of these extracts were determined as pyrocatechol equivalent and total flavonoids as quercetin equivalent. Antioxidant activity was determined by four complementary methods including inhibition of lipid peroxidation (by β-carotene color expression), DPPH free radical scavenging activity, ABTS cation radical scavenging activity and CUPRAC methods. Anticholinesterase activity of the extracts was investigated by the Ellman method against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. Viability and cytotoxic activity tests were carried out on the fibroblast L929 cells and cytotoxic A549 lung cancer cells, respectively. The triterpenoids and diterpenoids constitute the major secondary metabolites of the S. marashica acetone and methanol extracts isolated by chromatographic methods. Their structures were determined based on spectroscopic methods, namely NMR and mass analyses. Ten terpenoids were obtained from either acetone or methanol extracts of the S. marashica. Seven of them were triterpenoids, elucidated as lupeol, lupeol-3-acetate, lup-12, 20(29)-diene, lup-20(29)-ene, α-amyrin-tetracosanoate, oleanolic acid and ursolic acid besides a steroid β-sitosterol. Two abietane diterpenes, abieta-8,11,13-triene (1) and 18-acetoxymethylene-abieta-8,11,13-triene (2), were obtained from the acetone extract which were isolated from a Salvia species for the first time in the present study. The methanol extract was found to be very rich in rosmarinic acid determined by LC-MS/MS analysis.

scholarly journals A Comparison of Phytotoxic Potential among the Crude Extracts from Parthenium hysterophorus L. Extracted with Solvents of Increasing Polarity

2015 ◽  
Vol 33 ◽  
pp. 73-81 ◽  
Author(s):  
Ujjal Kumar Pati ◽  
Ashim Chowdhury
Keyword(s):  
Ethyl Acetate ◽  
Weed Management ◽  
Parthenium Hysterophorus ◽  
Weed Species ◽  
Methanol Extracts ◽  
Aerial Parts ◽  
Crude Extracts ◽  
Seed Germination Assay ◽  
Range Test

There is a worldwide search for the safe, effective and eco-friendly compounds of plant origin to combat the weed species and other pests which are responsible for the great impact on the growth and productivity of agricultural crops. In this present study, a comparison was made to evaluate the phytotoxicity potential of sequentially extracted solvent (hexane, ethyl-acetate, methanol) extracts of Parthenium hysterophorus L. (aerial parts) in vitro through bench-top seed germination assay (Vigna radiata L.). One-way analysis of variance (ANOVA) followed by Duncan’s multiple range test (DMRT) were done for statistical analysis of the data. The study reveals that germination, growth and vigour was significantly (P<0.05) reduced by ethyl-acetate and methanol extracts. The present study concluded that phytotoxicity of ethylacetate and methanolic crude extracts of Parthenium hysterophorus could be exploited as potential bioherbicide for future weed management programme and the development of bioherbicide for commercial use.

scholarly journals Study on tau-aggregation inhibitors in Alzheimer’s disease of methanol extracts of several medicinal plants collected in the Mekong Delta, Vietnam

2017 ◽  
Vol 1 (T2) ◽  
pp. 21-28
Author(s):  
Dua Kim Nguyen ◽  
Trang Thi Xuan Dai
Keyword(s):  
Tau Protein ◽  
Mekong Delta ◽  
Psidium Guajava ◽  
Nelumbo Nucifera ◽  
Artocarpus Altilis ◽  
Methanol Extracts ◽  
Aerial Parts ◽  
Ipomoea Aquatic ◽  
Tau Aggregation

Tau protein and Aβ-amyloid have been studied as pathological aggregations, which form neurofibrillary tangles and amyloid plaques in Alzheimer’s disease brain. Tau protein plays a critical role in neuron that binds to microtubules and assists with their formation and stabilization. However, unbinding of hyperphosphorylated tau and microtubules leads to unstable and disintegrating state of neuron. The free tau proteins form neurofibrillary tangles. The purpose of this study is to screen in vitro the the tau-aggregation inhibitory activity of nine methanol extracts of Psidium guajava leaf, Nelumbo nucifera leaf; wild Ipomoea aquatic, Cleome rutidosperma aerial parts, Artocarpus altilis leaf, cultivated Ipomoea aquatic, Centella asiatica leaf, Mimosa pudica L. aerial parts, Nelumbo nucifera seed pod collected in the Mekong Delta. Nine herbs were collected, dried and extracted with methanol. The half maximal inhibitory concentration (IC50) of methanol extracts was measured by Thioflavin T assay at various concentrations. Silica gel column chromatography was employed to fractionate the Psidium guajava leaf crude extract. Nine methanol extracts were proved to reduce the tau aggregation in vitro. Extracts from leaves of Psidium guajava, Artocarpus altilis and Nelumbo nucifera impressively inhibited the tau aggregation with IC50 at 0.39 mg/mL, 1.05 mg/mL and 1.24 mg/mL, respectively. Methylene blue was used as a positive control, with IC50 at 1.35 μM. The five examined fractions of guava leaf were proved to inhibit the tau aggregation ranging from 33.70 % to 48.49 %, except the 100 % of hexane fraction showed almost no effect on the tau aggregation inhibitor.

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