scholarly journals CaMKII comes of age in cardiac health and disease

2014 ◽  
Vol 5 ◽  
Author(s):  
Eleonora Grandi ◽  
Andrew G. Edwards ◽  
Anthony W. Herren ◽  
Donald M. Bers
Keyword(s):  
Cardiac Health ◽  
Health And Disease

scholarly journals Cross your heart? Collagen cross-links in cardiac health and disease

2021 ◽  
Vol 79 ◽  
pp. 109889
Author(s):  
Lily S. Neff ◽  
Amy D. Bradshaw
Keyword(s):  
Cardiac Health ◽  
Health And Disease ◽  
Cross Links

scholarly journals The Impact of Micronutrients-Calcium, Vitamin D, Selenium, Zinc in Cardiovascular Health: A Mini Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Harini Narayanam ◽  
Suresh V. Chinni ◽  
Sumitha Samuggam
Keyword(s):  
Vitamin D ◽  
Trace Elements ◽  
Cardiovascular Diseases ◽  
Observational Studies ◽  
Cardiovascular Health ◽  
Main Concern ◽  
Sudden Increase ◽  
Cardiac Health ◽  
Health And Disease ◽  
The Impact

The role of micronutrients in health and disease has increased the curiosity and interest among researchers. The prime focus of this review is the significance of trace elements- calcium, vitamin D, selenium and zinc with cardiovascular health. WHO identified cardiovascular diseases (CVD) as the leading cause of deaths globally. Identifying the risk factors that could be modified and creating new treatment strategies remains to be the main concern for CVD prevention. The data that showed the relationship between trace elements and various ways in which they may contribute to cardiovascular health and disease from clinical trials and observational studies were collected from databases such as PubMed and Embase. Based on these collected data, it shows that either high or low circulating serum levels can be associated with the development of cardiovascular diseases. Micronutrients through diet contribute to improved cardiac health. However, due to our current lifestyle, there is a huge dependency on dietary supplements. Based on the observational studies, it is evident that supplements cause sudden increase in the circulating levels of the nutrients and result in cardiovascular damage. Thus, it is advisable to restrict the use of supplements, owing to the potent risks it may cause. In order to understand the exact mechanism between micronutrients and cardiac health, more clinical studies are required.

A hemodynamic analysis of coronary capillary blood flow based on anatomic and distensibility data

1999 ◽  
Vol 277 (6) ◽  
pp. H2158-H2166 ◽  
Author(s):  
Ghassan S. Kassab ◽  
Kha N. Le ◽  
Yuan-Cheng B. Fung
Keyword(s):  
Blood Flow ◽  
Capillary Blood ◽  
Capillary Network ◽  
Capillary Blood Flow ◽  
Cardiac Health ◽  
Epicardial Surface ◽  
Health And Disease ◽  
Complete Set ◽  
Vascular Geometry ◽  
Physical Laws

An understanding of cardiac health and disease requires knowledge of the various factors that control coronary capillary blood flow. An analysis of coronary capillary blood flow based on a complete set of actual data on the capillary anatomy and elasticity does not exist. Previously, a complete set of data on the branching pattern and the vascular geometry of the pig coronary capillary network were obtained in our laboratory. In the present study, we obtained distensibility data on the coronary capillary blood vessels on the epicardial surface in the form of a pressure-diameter relationship using intravital microscopy. A mathematical model of the coronary capillary blood flow was then constructed on the basis of measured anatomic and elasticity data of the coronary capillary network, rheology of blood, physical laws governing blood flow, and appropriate boundary conditions. The constructed model was used to examine the heterogeneity of the spatial distribution of coronary blood flow, which is an important issue in coronary physiology. One interesting result of the model is that the dispersions of pressure and flow are significantly reduced in the presence of capillary cross-connections, and the resistance to flow is reduced as well. Finally, we found that the compliance of the epicardial surface capillary vessels is so small that its effect on the blood pressure drop is negligible in the diastolic state. However, the compliance of the intramyocardial capillaries remains unknown, and the interaction of the muscle contraction and blood vessel elasticity in systole remains to be studied.

EXPRESSION OF TYPE 2A PROTEIN PHOSPHATASES IN CARDIAC HEALTH AND DISEASE

Heart ◽  
2014 ◽  
Vol 100 (Suppl 4) ◽  
pp. A16.2-A16 ◽  
Author(s):  
O Eleftheriadou ◽  
MR Longman ◽  
A Boguslavskyi ◽  
A Ryan ◽  
BE Wadzinski ◽  
...  
Keyword(s):  
Protein Phosphatases ◽  
Cardiac Health ◽  
Health And Disease

scholarly journals Lipid Raft in Cardiac Health and Disease

2009 ◽  
Vol 5 (2) ◽  
pp. 105-111 ◽  
Author(s):  
Manika Das ◽  
Dipak Das
Keyword(s):  
Lipid Raft ◽  
Cardiac Health ◽  
Health And Disease
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