scholarly journals An Emerging Molecular Understanding and Novel Targeted Treatment Approaches in Pediatric Kidney Diseases

2014 ◽  
Vol 2 ◽  
Author(s):  
Max Christoph Liebau
Keyword(s):  
Kidney Diseases ◽  
Targeted Treatment ◽  
Treatment Approaches ◽  
Pediatric Kidney Diseases

scholarly journals Enhancing clinical trial development for pediatric kidney diseases

2017 ◽  
Vol 82 (5) ◽  
pp. 727-732 ◽  
Author(s):  
H William Schnaper ◽  
Joseph T Flynn ◽  
Coleman Gross ◽  
Anne B Cropp ◽  
Bastian Dehmel ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Kidney Diseases ◽  
Pediatric Kidney Diseases

scholarly journals Targeted treatment approaches in refractory germ cell tumors

2019 ◽  
Vol 143 ◽  
pp. 130-138 ◽  
Author(s):  
Laura Galvez-Carvajal ◽  
Alfonso Sanchez-Muñoz ◽  
Nuria Ribelles ◽  
Maribel Saez ◽  
Javier Baena ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Targeted Treatment ◽  
Treatment Approaches

scholarly journals A systematic review of modeling and simulation approaches in designing targeted treatment technologies for Leukemia Cancer in low and middle income countries

2021 ◽  
Vol 18 (6) ◽  
pp. 8149-8173
Author(s):  
Henry Fenekansi Kiwumulo ◽  
◽  
Haruna Muwonge ◽  
Charles Ibingira ◽  
John Baptist Kirabira ◽  
...  
Keyword(s):  
Systematic Review ◽  
Modeling And Simulation ◽  
The Body ◽  
Targeted Treatment ◽  
Middle Income ◽  
Treatment Approaches ◽  
Middle Income Countries ◽  
Targeted Drug ◽  
Virtual Experimentation ◽  
Low And Middle Income

<abstract> <p>Virtual experimentation is a widely used approach for predicting systems behaviour especially in situations where resources for physical experiments are very limited. For example, targeted treatment inside the human body is particularly challenging, and as such, modeling and simulation is utilised to aid planning before a specific treatment is administered. In such approaches, precise treatment, as it is the case in radiotherapy, is used to administer a maximum dose to the infected regions while minimizing the effect on normal tissue. Complicated cancers such as leukemia present even greater challenges due to their presentation in liquid form and not being localised in one area. As such, science has led to the development of targeted drug delivery, where the infected cells can be specifically targeted anywhere in the body.</p> <p>Despite the great prospects and advances of these modeling and simulation tools in the design and delivery of targeted drugs, their use by Low and Middle Income Countries (LMICs) researchers and clinicians is still very limited. This paper therefore reviews the modeling and simulation approaches for leukemia treatment using nanoparticles as an example for virtual experimentation. A systematic review from various databases was carried out for studies that involved cancer treatment approaches through modeling and simulation with emphasis to data collected from LMICs. Results indicated that whereas there is an increasing trend in the use of modeling and simulation approaches, their uptake in LMICs is still limited. According to the review data collected, there is a clear need to employ these tools as key approaches for the planning of targeted drug treatment approaches.</p> </abstract>

Epidemiology of Pediatric Kidney Diseases

1996 ◽  
Vol 25 (5) ◽  
pp. 288-296 ◽  
Author(s):  
Robert J Wyatt ◽  
Lori Kagy ◽  
Stephen B Kritchevsky
Keyword(s):  
Kidney Diseases ◽  
Pediatric Kidney Diseases

Novel Targeted Treatment Approaches in Pancreatic Cancer

2019 ◽  
pp. 479-491
Author(s):  
Maria Diab ◽  
Muhammad Saad Hamid ◽  
Ramzi M. Mohammad ◽  
Philip A. Philip ◽  
Asfar S. Azmi
Keyword(s):  
Pancreatic Cancer ◽  
Targeted Treatment ◽  
Treatment Approaches

scholarly journals Kidney diseases in children – early diagnosis and prevention

PRILOZI ◽  
2016 ◽  
Vol 37 (1) ◽  
pp. 5-7
Author(s):  
Momir Polenakovic ◽  
Zoran Gucev ◽  
Velibor Tasic
Keyword(s):  
Urinary Tract ◽  
Early Diagnosis ◽  
Health Professionals ◽  
Kidney Diseases ◽  
Healthy Life ◽  
The World ◽  
Interactive Lectures ◽  
Healthy Life Style ◽  
The Media ◽  
Pediatric Kidney Diseases

Abstract Pediatric kidney diseases were in the focus of the World Kidney Day 2016. Macedonian pediatric nephrologists gave their contribution with public appearance in kindergartens, primary and secondary schools, with interactive lectures and discussion with the youngest about the kidney function, healthy life style and simple measures to prevent kidney and urinary tract diseases. Besides promotive appearance in the media, series of lectures were presented in front of the health professionals. The aim was to attract the attention of the professionals for early diagnosis and prevention of kidney disease. The action starts in utero, followed by early postnatal imaging and assessment, conservative treatment and in selected cases surgical treatment. The emphasis is on the multidisciplinary and comprehensive approach to children and adolescents with kidney diseases.

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