scholarly journals Navy Bean and Rice Bran Intake Alters the Plasma Metabolome of Children at Risk for Cardiovascular Disease

2018 ◽  
Vol 4 ◽  
Author(s):  
Katherine J. Li ◽  
Erica C. Borresen ◽  
NaNet Jenkins-Puccetti ◽  
Gary Luckasen ◽  
Elizabeth P. Ryan
Author(s):  
Marina Ybarra ◽  
Prince Kevin Danieles ◽  
Tracie A Barnett ◽  
Marie-Ève Mathieu ◽  
Andraea Van Hulst ◽  
...  

Abstract Objectives Obesity is the most prevalent risk factor for cardiovascular disease (CVD) in children. We developed a 2-year lifestyle intervention for youth at risk of CVD. We assessed changes in body mass index z-scores (zBMI) and key cardiometabolic risk factors, physical fitness, and capacity among those who completed the program. Methods The CIRCUIT program is a multidisciplinary lifestyle intervention for children aged 4 to 18 years at risk of CVD, based on a personalized plan to improve cardiometabolic outcomes by increasing physical activity and reducing sedentary behaviours. Both at baseline and 2-year follow-up, we measured zBMI, blood pressure z-scores (zBP), adiposity (%body and %trunk fat), fasting blood glucose and lipid profile, aerobic (VO2max) and anaerobic (5×5 m shuttle run test) fitness, and physical capacity indicators. Differences between baseline and follow-up were examined using paired t-tests (for age-sex standardized outcomes) and multivariable mixed effect models, adjusted for age and sex (for other outcomes). Results Among the 106 participants (53 males) who completed the 2-year program, mean age at baseline was 10.9 years (SD=3.2). After 2 years, zBMI and diastolic zBP decreased by 0.30SD (95% CI: −0.44; −0.16) and 0.43SD (95% CI: −0.65; −0.23), respectively. Participants improved %body and %trunk fat, lipid profile, aerobic and anaerobic fitness levels, and physical capacity (p<0.02). No changes in systolic zBP nor in fasting plasma glucose were observed. Conclusion Our findings showed improved zBMI, cardiometabolic outcomes, physical fitness, and capacity among children at risk of CVD, suggesting that CIRCUIT is a promising intervention.


2005 ◽  
Vol 18 (4) ◽  
pp. 213-220 ◽  
Author(s):  
P. Velasquez-Mieyer ◽  
S. Perez-Faustinelli ◽  
P. A. Cowan

PEDIATRICS ◽  
1980 ◽  
Vol 65 (3) ◽  
pp. 674-675
Author(s):  
Neil A. Holtzman

Let me first repeat what I said about children with a family history of premature cardiovascular disease: By restricting cholesterol testing to those with positive family histories, fewer children will be unnecessarily treated, but whether those at risk will benefit from learning of the high probability that they will develop coronary disease or from diet modification is still unknown. I agree with Dr Freis on the need for more information. Until that information is forthcoming I cannot agree that proper patient management involves labeling children at risk, selectively modifying their diets, or treating them with cholesterol-lowering drugs.


2000 ◽  
Vol 16 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Padeliadu Susana ◽  
Georgios D. Sideridis

Abstract This study investigated the discriminant validation of the Test of Reading Performance (TORP), a new scale designed to evaluate the reading performance of elementary-school students. The sample consisted of 181 elementary-school students drawn from public elementary schools in northern Greece using stratified random procedures. The TORP was hypothesized to measure six constructs, namely: “letter knowledge,” “phoneme blending,” “word identification,” “syntax,” “morphology,” and “passage comprehension.” Using standard deviations (SD) from the mean, three groups of students were formed as follows: A group of low achievers in reading (N = 9) including students who scored between -1 and -1.5 SD from the mean of the group. A group of students at risk of reading difficulties (N = 6) including students who scored between -1.5 and -2 SDs below the mean of the group. A group of students at risk of serious reading difficulties (N = 6) including students who scored -2 or more SDs below the mean of the group. The rest of the students (no risk, N = 122) comprised the fourth group. Using discriminant analyses it was evaluated how well the linear combination of the 15 variables that comprised the TORP could discriminate students of different reading ability. Results indicated that correct classification rates for low achievers, those at risk for reading problems, those at risk of serious reading problems, and the no-risk group were 89%, 100%, 83%, and 97%, respectively. Evidence for partial validation of the TORP was provided through the use of confirmatory factor analysis and indices of sensitivity and specificity. It is concluded that the TORP can be ut ilized for the identification of children at risk for low achievement in reading. Analysis of the misclassified cases indicated that increased variability might have been responsible for the existing misclassification. More research is needed to determine the discriminant validation of TORP with samples of children with specific reading disabilities.


PsycCRITIQUES ◽  
2014 ◽  
Vol 59 (8) ◽  
Author(s):  
Richard Thompson ◽  
Elizabeth C. Neilson
Keyword(s):  
At Risk ◽  

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