scholarly journals Bone Mineral Density after Weight Gain in 160 Patients with Anorexia Nervosa

2017 ◽  
Vol 4 ◽  
Author(s):  
Najate Achamrah ◽  
Moïse Coëffier ◽  
Pierre Jésus ◽  
Jocelyne Charles ◽  
Agnès Rimbert ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Anorexia Nervosa ◽  
Weight Gain ◽  
Bone Mineral ◽  
Mineral Density

scholarly journals Bone Mineral Density Accrual Determines Energy Expenditure with Refeeding in Anorexia Nervosa and Supersedes Return of Menses

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Melissa Sum ◽  
Laurel Mayer ◽  
Michelle P. Warren
Keyword(s):  
Bone Mineral Density ◽  
Anorexia Nervosa ◽  
Weight Gain ◽  
Energy Expenditure ◽  
Bone Formation ◽  
Bone Mineral ◽  
Subgroup Analysis ◽  
Resting Energy Expenditure ◽  
Nutritional Rehabilitation ◽  
Mineral Density

Osteopenia and osteoporosis are major complications of anorexia nervosa (AN). Since bone is a tissue requiring large amounts of energy, we examined the disproportionate increase in resting energy expenditure (REE) that occurs with refeeding of AN patients to determine if it was related to bone accretion. Thirty-seven AN patients aged23.4±4.8years underwent a behavioral weight-gain protocol lasting a median of 66 days; 27 remained amenorrheic, and 10 regained menses. Sixteen controls aged25.1±4.7years were age- and % IBW matched with patients. REE was measured using a respiratory chamber-indirect calorimeter. Significant correlations were found between REE and changes in spine (r=0.48,P<0.02) and leg (r=0.43,P<0.05) BMDs in AN patients. Further subgroup analysis of the amenorrheics revealed significant correlation between REE and change in spine BMD (r=0.59,P<0.02) and higher IGF-1 after weight gain compared to controls. Amenorrheics also had lower BMDs. These findings were absent in the regained menses group. The increase in REE seen in women with AN during nutritional rehabilitation may be related to active bone formation, which is not as prominent when menses have returned.

scholarly journals The Association between Weight Gain/Restoration and Bone Mineral Density in Adolescents with Anorexia Nervosa: A Systematic Review

Nutrients ◽  
2016 ◽  
Vol 8 (12) ◽  
pp. 769 ◽  
Author(s):  
Marwan El Ghoch ◽  
Davide Gatti ◽  
Simona Calugi ◽  
Ombretta Viapiana ◽  
Paola Bazzani ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Systematic Review ◽  
Anorexia Nervosa ◽  
Weight Gain ◽  
Bone Mineral ◽  
Mineral Density

scholarly journals Weight Gain and Restoration of Menses as Predictors of Bone Mineral Density Change in Adolescent Girls with Anorexia Nervosa-1

2008 ◽  
Vol 93 (4) ◽  
pp. 1231-1237 ◽  
Author(s):  
Madhusmita Misra ◽  
Rajani Prabhakaran ◽  
Karen K. Miller ◽  
Mark A. Goldstein ◽  
Diane Mickley ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Anorexia Nervosa ◽  
Weight Gain ◽  
Bone Mineral ◽  
Adolescent Girls ◽  
Density Change ◽  
Bone Mineral Density Change ◽  
Mineral Density

Bone mineral density and oxidative stress in adolescent girls with anorexia nervosa

2021 ◽  
Author(s):  
Alžbeta Čagalová ◽  
Ľubica Tichá ◽  
Alexandra Gaál Kovalčíková ◽  
Katarína Šebeková ◽  
Ľudmila Podracká
Keyword(s):  
Oxidative Stress ◽  
Bone Mineral Density ◽  
Anorexia Nervosa ◽  
Bone Mineral ◽  
Adolescent Girls ◽  
Mineral Density ◽  
And Oxidative Stress

scholarly journals Teriparatide Increases Bone Formation and Bone Mineral Density in Adult Women With Anorexia Nervosa

2014 ◽  
Vol 99 (4) ◽  
pp. 1322-1329 ◽  
Author(s):  
Pouneh K. Fazeli ◽  
Irene S. Wang ◽  
Karen K. Miller ◽  
David B. Herzog ◽  
Madhusmita Misra ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Anorexia Nervosa ◽  
Bone Formation ◽  
Bone Mineral ◽  
Adult Women ◽  
Mineral Density

Decreased Bone Density in Adolescent Girls With Anorexia Nervosa

PEDIATRICS ◽  
1990 ◽  
Vol 86 (3) ◽  
pp. 440-447 ◽  
Author(s):  
Laura K. Bachrach ◽  
David Guido ◽  
Debra Katzman ◽  
Iris F. Litt ◽  
Robert Marcus
Keyword(s):  
Bone Mineral Density ◽  
Body Mass Index ◽  
Anorexia Nervosa ◽  
Bone Density ◽  
Bone Mass ◽  
Body Mass ◽  
Bone Mineral ◽  
Whole Body ◽  
Mineral Density ◽  
Control Subjects

Osteoporosis develops in women with chronic anorexia nervosa. To determine whether bone mass is reduced in younger patients as well, bone density was studied in a group of adolescent patients with anorexia nervosa. With single- and dual-photon absorptiometry, a comparison was made of bone mineral density of midradius, lumbar spine, and whole body in 18 girls (12 to 20 years of age) with anorexia nervosa and 25 healthy control subjects of comparable age. Patients had significantly lower lumbar vertebral bone density than did control subjects (0.830 ± 0.140 vs 1.054 ± 0.139 g/cm2) and significantly lower whole body bone mass (0.700 ± 0.130 vs 0.955 ± 0.130 g/cm2). Midradius bone density was not significantly reduced. Of 18 patients, 12 had bone density greater than 2 standard deviations less than normal values for age. The diagnosis of anorexia nervosa had been made less than 1 year earlier for half of these girls. Body mass index correlated significantly with bone mass in girls who were not anorexic (P &lt; .05, .005, and .0001 for lumbar, radius, and whole body, respectively). Bone mineral correlated significantly with body mass index in patients with anorexia nervosa as well. In addition, age at onset and duration of anorexia nervosa, but not calcium intake, activity level, or duration of amenorrhea correlated significantly with bone mineral density. It was concluded that important deficits of bone mass occur as a frequent and often early complication of anorexia nervosa in adolescence. Whole body is considerably more sensitive than midradius bone density as a measure of cortical bone loss in this illness. Low body mass index is an important predictor of this reduction in bone mass.

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