scholarly journals Bidirectional interactions between neuronal and hemodynamic responses to transcranial direct current stimulation (tDCS): challenges for brain-state dependent tDCS

2015 ◽  
Vol 9 ◽  
Author(s):  
Anirban Dutta
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Brain State ◽  
Hemodynamic Responses ◽  
Direct Current Stimulation ◽  
State Dependent ◽  
Bidirectional Interactions

scholarly journals Brain state and polarity dependent modulation of brain networks by transcranial direct current stimulation

2017 ◽  
Author(s):  
Lucia M. Li ◽  
Ines R. Violante ◽  
Rob Leech ◽  
Ewan Ross ◽  
Adam Hampshire ◽  
...  
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Large Scale ◽  
Inferior Frontal Gyrus ◽  
Brain Networks ◽  
Cognitive Networks ◽  
Network Activity ◽  
Brain State ◽  
Direct Current Stimulation ◽  
Network Activation

AbstractTranscranial direct current stimulation (TDCS) has been widely used to improve cognitive function. However, current deficiencies in mechanistic understanding hinders wider applicability. To clarify its physiological effects, we acquired fMRI whilst simultaneously acquiring TDCS to the right inferior frontal gyrus (rIFG) of healthy human participants, a region involved in coordinating activity within brain networks. TDCS caused widespread modulation of network activity depending on brain state (‘rest’ or choice reaction time task) and polarity (anodal or cathodal). During task, TDCS increased salience network activation and default mode network deactivation, but had the opposite effect during ‘rest’. Furthermore, there was an interaction between brain state and TDCS polarity, with cathodal effects more pronounced during task performance and anodal effects more pronounced during ‘rest’. Overall, we show that rIFG TDCS produces brain state and polarity dependent effects within large-scale cognitive networks, in a manner that goes beyond predictions from the current literature.

scholarly journals Effects of Transcranial Direct Current Stimulation (tDCS) on Cognitive Performance and Cerebral Oxygen Hemodynamics: A Systematic Review

2021 ◽  
Vol 15 ◽  
Author(s):  
Mathieu Figeys ◽  
Michael Zeeman ◽  
Esther Sung Kim
Keyword(s):  
Cognitive Performance ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Cognitive Aging ◽  
Cerebral Perfusion ◽  
Near Infrared ◽  
Neurovascular Unit ◽  
Hemodynamic Responses ◽  
Functional Near Infrared Spectroscopy ◽  
Direct Current Stimulation

Background: There is increasing evidence to support the efficacy of transcranial direct current stimulation (tDCS) applications in cognitive augmentation and rehabilitation. Neuromodulation achieved with tDCS may further regulate regional cerebral perfusion affiliated through the neurovascular unit; however, components of cerebral perfusion decrease across aging. A novel neuroimaging approach, functional near-infrared spectroscopy (fNIRS), can aid in quantifying these regional perfusional changes. To date, the interaction of the effects of tDCS on cognitive performance across the lifespan and obtained fNIRS hemodynamic responses remain unknown.Objective: This review aims to examine the effects of tDCS on cognitive performance and fNIRS hemodynamic responses within the context of cognitive aging.Methods: Six databases were searched for studies. Quality appraisal and data extraction were conducted by two independent reviewers. Meta-analysis was carried out to determine overall and subgroup effect sizes.Results: Eight studies met inclusion criteria. The overall effect size demonstrates that tDCS can alter cognitive performance and fNIRS signals, with aging being a potential intermediary in tDCS efficacy.Conclusion: From the studies included, the effects of tDCS on cognitive performance and fNIRS metrics are most prominent in young healthy adults and appear to become less robust with increasing age. Given the small number of studies included in this review further investigation is recommended.

scholarly journals Brain state and polarity dependent modulation of brain networks by transcranial direct current stimulation

2018 ◽  
Vol 40 (3) ◽  
pp. 904-915 ◽  
Author(s):  
Lucia M. Li ◽  
Ines R. Violante ◽  
Rob Leech ◽  
Ewan Ross ◽  
Adam Hampshire ◽  
...  
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Brain Networks ◽  
Brain State ◽  
Direct Current Stimulation

scholarly journals State dependent effect of transcranial direct current stimulation (tDCS) on methamphetamine craving

2014 ◽  
Vol 17 (10) ◽  
pp. 1591-1598 ◽  
Author(s):  
Alireza Shahbabaie ◽  
Mehrshad Golesorkhi ◽  
Behnam Zamanian ◽  
Mitra Ebrahimpoor ◽  
Fatemeh Keshvari ◽  
...  
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Dependent Effect ◽  
Direct Current Stimulation ◽  
State Dependent
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