scholarly journals Neural Network-Based Muscle Torque Estimation Using Mechanomyography During Electrically-Evoked Knee Extension and Standing in Spinal Cord Injury

2018 ◽  
Vol 12 ◽  
Author(s):  
Muhammad Afiq Dzulkifli ◽  
Nur Azah Hamzaid ◽  
Glen M. Davis ◽  
Nazirah Hasnan
Keyword(s):  
Neural Network ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Knee Extension ◽  
Muscle Torque ◽  
Torque Estimation ◽  
Cord Injury

Spastic Reflexes Triggered by Ankle Load Release in Human Spinal Cord Injury

2006 ◽  
Vol 96 (6) ◽  
pp. 2941-2950 ◽  
Author(s):  
Ming Wu ◽  
Brian D. Schmit
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Human Movement ◽  
Knee Extension ◽  
Muscle Afferents ◽  
Spinal Reflex ◽  
Joint Torques ◽  
Human Spinal Cord ◽  
Cord Injury ◽  
Load Release

The rapid decrease in firing of load-sensitive group Ib muscle afferents during unloading may be particularly important in triggering the swing phase of gait. However, it still remains unclear whether load-sensitive muscle afferents modulate reflex activity in human spinal cord injury (SCI), as suggested by studies in the cat. The right hip of 12 individuals with chronic SCI was subjected to ramp (60°/s) and hold (10 s) movements over a range from 40° flexion to 0–10°extension using a custom servomotor system. An ankle dorsiflexion load was imposed and released after the hip reached a targeted position using a custom-designed pneumatic motor system. Isometric joint torques of the hip and knee, reaction torque of the ankle, and surface electromyograms (EMGs) from eight muscles of the leg were recorded following the imposed hip movement and ankle load release. Reflexes, characterized by hip flexion torque, knee extension, and coactivation of ankle flexors and extensors, were triggered by ankle load release when the hip was in an extended position. The ankle load release was observed to enhance the reflexes triggered by hip extension itself, suggesting that ankle load afferents play an important role in spastic reflexes in human SCI and that the reflex pathways associated with ankle load afferents have important implications in the spinal reflex regulation of human movement. Such muscle behaviors emphasize the role of ankle load afferents and hip proprioceptors on locomotion. This knowledge may be especially helpful in the treatment of spasms and in identifying rehabilitation strategies for producing functional movements in human SCI.

scholarly journals Recovery of paralyzed limb motor function in canine with complete spinal cord injury following implantation of MSC-derived neural network tissue

Biomaterials ◽  
2018 ◽  
Vol 181 ◽  
pp. 15-34 ◽  
Author(s):  
Guo-Hui Wu ◽  
Hui-Juan Shi ◽  
Ming-Tian Che ◽  
Meng-Yao Huang ◽  
Qing-Shuai Wei ◽  
...  
Keyword(s):  
Neural Network ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Motor Function ◽  
Cord Injury ◽  
Complete Spinal Cord Injury

scholarly journals Assessment of Hyperactive Reflexes in Patients with Spinal Cord Injury

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Dali Xu ◽  
Xin Guo ◽  
Chung-Yong Yang ◽  
Li-Qun Zhang
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Patellar Tendon ◽  
Knee Extension ◽  
Clinical Settings ◽  
Tendon Reflex ◽  
Cord Injury ◽  
Reflex Gain ◽  
Healthy Control ◽  
Tendon Reflexes

Hyperactive reflexes are commonly observed in patients with spinal cord injury (SCI) but there is a lack of convenient and quantitative characterizations. Patellar tendon reflexes were examined in nine SCI patients and ten healthy control subjects by tapping the tendon using a hand-held instrumented hammer at various knee flexion angles, and the tapping force, quadriceps EMG, and knee extension torque were measured to characterize patellar tendon reflexes quantitatively in terms of the tendon reflex gain (Gtr), contraction rate (Rc), and reflex loop time delay (td). It was found that there are significant increases inGtrandRcand decrease intdin patients with spinal cord injury as compared to the controls (P<0.05). This study presented a convenient and quantitative method to evaluate reflex excitability and muscle contraction dynamics. With proper simplifications, it can potentially be used for quantitative diagnosis and outcome evaluations of hyperreflexia in clinical settings.

Extensor spasms triggered by imposed knee extension in chronic human spinal cord injury

2004 ◽  
Vol 162 (2) ◽  
pp. 239-249 ◽  
Author(s):  
Ming Wu ◽  
T. George Hornby ◽  
Jennifer Hilb ◽  
Brian D. Schmit
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Knee Extension ◽  
Human Spinal Cord ◽  
Cord Injury
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