scholarly journals Noradrenergic activation of the basolateral amygdala enhances object recognition memory and induces chromatin remodeling in the insular cortex

2015 ◽  
Vol 9 ◽  
Author(s):  
Hassiba Beldjoud ◽  
Areg Barsegyan ◽  
Benno Roozendaal
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Chromatin Remodeling ◽  
Basolateral Amygdala ◽  
Insular Cortex ◽  
Object Recognition Memory

CB1 receptor antagonism in the granular insular cortex or somatosensory area facilitates consolidation of object recognition memory

2014 ◽  
Vol 578 ◽  
pp. 192-196 ◽  
Author(s):  
Lesley D. O’Brien ◽  
Martin A. Sticht ◽  
Krista A. Mitchnick ◽  
Cheryl L. Limebeer ◽  
Linda A. Parker ◽  
...  
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Insular Cortex ◽  
Cb1 Receptor ◽  
Receptor Antagonism ◽  
Somatosensory Area ◽  
Object Recognition Memory

scholarly journals Chemogenetic silencing of hippocampus and amygdala reveals a double dissociation in periadolescent obesogenic diet-induced memory alterations

2020 ◽  
Author(s):  
Fabien Naneix ◽  
Ioannis Bakoyiannis ◽  
Marianela Santoyo-Zedillo ◽  
Clémentine Bosch-Bouju ◽  
Gustavo Pacheco-Lopez ◽  
...  
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Basolateral Amygdala ◽  
Memory Deficits ◽  
Ventral Hippocampus ◽  
Brain Regions ◽  
Obesity Prevalence ◽  
Odor Aversion ◽  
Object Recognition Memory

1ABSTRACTIn addition to numerous metabolic comorbidities, obesity is associated with several adverse neurobiological outcomes, especially learning and memory alterations. Obesity prevalence is rising dramatically in youth and is persisting in adulthood. This is especially worrying since adolescence is a crucial period for the maturation of certain brain regions playing a central role in memory processes such as the hippocampus and the amygdala. We previously showed that periadolescent exposure to obesogenic high-fat diet (HFD) had opposite effects on hippocampus- and amygdala-dependent memory, impairing the former and enhancing the latter. However, the causal role of these two brain regions in periadolescent HFD-induced memory alterations remains unclear. Here, we first showed that periadolescent HFD induced long-term, but not short-term, object recognition memory deficits, specifically when rats were exposed to a novel context. Using chemogenetic approaches to inhibit targeted brain regions, we then demonstrated that recognition memory deficits are dependent on the activity of the ventral hippocampus, but not the basolateral amygdala. On the contrary, the HFD-induced enhancement of conditioned odor aversion requires specifically amygdala activity. Taken together, these findings suggest that HFD consumption throughout adolescence impairs long-term object recognition memory through the overactivation of the ventral hippocampus during memory acquisition. Moreover, these results further highlight the bidirectional effects of adolescent HFD on hippocampal and amygdala functions.

scholarly journals Noradrenergic activation of the basolateral amygdala modulates consolidation of object recognition memory☆

2008 ◽  
Vol 90 (3) ◽  
pp. 576-579 ◽  
Author(s):  
Benno Roozendaal ◽  
Nicholas A. Castello ◽  
Gustavo Vedana ◽  
Areg Barsegyan ◽  
James L. McGaugh
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Basolateral Amygdala ◽  
Object Recognition Memory

Class I HDAC inhibition improves object recognition memory consolidation through BDNF/TrkB pathway in a time-dependent manner

2021 ◽  
Vol 187 ◽  
pp. 108493
Author(s):  
Gerardo Ramirez-Mejia ◽  
Elvi Gil-Lievana ◽  
Oscar Urrego-Morales ◽  
Ernesto Soto-Reyes ◽  
Federico Bermúdez-Rattoni
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Memory Consolidation ◽  
Time Dependent ◽  
Class I ◽  
Dependent Manner ◽  
Hdac Inhibition ◽  
Object Recognition Memory
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