Blockade of intracellular Zn 2+ signaling in the basolateral amygdala affects object recognition memory via attenuation of dentate gyrus LTP

2017 ◽  
Vol 108 ◽  
pp. 1-6 ◽  
Author(s):  
Yuki Fujise ◽  
Mitsuyasu Kubota ◽  
Miki Suzuki ◽  
Haruna Tamano ◽  
Atsushi Takeda
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Dentate Gyrus ◽  
Basolateral Amygdala ◽  
Object Recognition Memory

scholarly journals The impact of ageing reveals distinct roles for human dentate gyrus and CA3 in pattern separation and object recognition memory

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Serena E. Dillon ◽  
Demitra Tsivos ◽  
Michael Knight ◽  
Bryony McCann ◽  
Catherine Pennington ◽  
...  
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Dentate Gyrus ◽  
Pattern Separation ◽  
Object Recognition Memory ◽  
The Impact

Intracellular Zn2+signaling in the dentate gyrus is required for object recognition memory

Hippocampus ◽  
2014 ◽  
Vol 24 (11) ◽  
pp. 1404-1412 ◽  
Author(s):  
Atsushi Takeda ◽  
Haruna Tamano ◽  
Taisuke Ogawa ◽  
Shunsuke Takada ◽  
Masatoshi Nakamura ◽  
...  
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Dentate Gyrus ◽  
Object Recognition Memory

scholarly journals Chemogenetic silencing of hippocampus and amygdala reveals a double dissociation in periadolescent obesogenic diet-induced memory alterations

2020 ◽  
Author(s):  
Fabien Naneix ◽  
Ioannis Bakoyiannis ◽  
Marianela Santoyo-Zedillo ◽  
Clémentine Bosch-Bouju ◽  
Gustavo Pacheco-Lopez ◽  
...  
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Basolateral Amygdala ◽  
Memory Deficits ◽  
Ventral Hippocampus ◽  
Brain Regions ◽  
Obesity Prevalence ◽  
Odor Aversion ◽  
Object Recognition Memory

1ABSTRACTIn addition to numerous metabolic comorbidities, obesity is associated with several adverse neurobiological outcomes, especially learning and memory alterations. Obesity prevalence is rising dramatically in youth and is persisting in adulthood. This is especially worrying since adolescence is a crucial period for the maturation of certain brain regions playing a central role in memory processes such as the hippocampus and the amygdala. We previously showed that periadolescent exposure to obesogenic high-fat diet (HFD) had opposite effects on hippocampus- and amygdala-dependent memory, impairing the former and enhancing the latter. However, the causal role of these two brain regions in periadolescent HFD-induced memory alterations remains unclear. Here, we first showed that periadolescent HFD induced long-term, but not short-term, object recognition memory deficits, specifically when rats were exposed to a novel context. Using chemogenetic approaches to inhibit targeted brain regions, we then demonstrated that recognition memory deficits are dependent on the activity of the ventral hippocampus, but not the basolateral amygdala. On the contrary, the HFD-induced enhancement of conditioned odor aversion requires specifically amygdala activity. Taken together, these findings suggest that HFD consumption throughout adolescence impairs long-term object recognition memory through the overactivation of the ventral hippocampus during memory acquisition. Moreover, these results further highlight the bidirectional effects of adolescent HFD on hippocampal and amygdala functions.

scholarly journals Noradrenergic activation of the basolateral amygdala modulates consolidation of object recognition memory☆

2008 ◽  
Vol 90 (3) ◽  
pp. 576-579 ◽  
Author(s):  
Benno Roozendaal ◽  
Nicholas A. Castello ◽  
Gustavo Vedana ◽  
Areg Barsegyan ◽  
James L. McGaugh
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Basolateral Amygdala ◽  
Object Recognition Memory

scholarly journals Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

2009 ◽  
Vol 16 (2) ◽  
pp. 147-154 ◽  
Author(s):  
S. Jessberger ◽  
R. E. Clark ◽  
N. J. Broadbent ◽  
G. D. Clemenson ◽  
A. Consiglio ◽  
...  
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Dentate Gyrus ◽  
Adult Neurogenesis ◽  
Adult Rats ◽  
Object Recognition Memory
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