scholarly journals Lipoprotein SPD_1609 of Streptococcus pneumoniae Promotes Adherence and Invasion to Epithelial Cells Contributing to Bacterial Virulence

2019 ◽  
Vol 10 ◽  
Author(s):  
Xiao-Yan Yang ◽  
Nan Li ◽  
Jing-Yu Xu ◽  
Xuesong Sun ◽  
Qing-Yu He
2008 ◽  
Vol 1 (1) ◽  
pp. 64 ◽  
Author(s):  
Xin-Ming Song ◽  
Wayne Connor ◽  
Karsten Hokamp ◽  
Lorne A Babiuk ◽  
Andrew A Potter

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e90066 ◽  
Author(s):  
Kang Ouyang ◽  
Shireen A. Woodiga ◽  
Varun Dwivedi ◽  
Carolyn M. Buckwalter ◽  
Anirudh K. Singh ◽  
...  

2003 ◽  
Vol 34 (6) ◽  
pp. 261-265 ◽  
Author(s):  
Gulcin Cakan ◽  
Mustafa Turkoz ◽  
Tolga Turan ◽  
Kamruddin Ahmed ◽  
Tsuyoshi Nagatake

mBio ◽  
2021 ◽  
Author(s):  
Saigopalakrishna S. Yerneni ◽  
Sarah Werner ◽  
Juliana H. Azambuja ◽  
Nils Ludwig ◽  
Rory Eutsey ◽  
...  

Our studies reveal that Streptococcus pneumoniae (pneumococcus) (pEVs) are internalized by macrophages, T cells, and epithelial cells. In vitro , pEVs induce NF-κB activation in a dosage-dependent manner and polarize human macrophages to an alternative (M2) phenotype. In addition, pEV pretreatment conditions macrophages to increase bacteria uptake and such macrophages may act as a reservoir for pneumococcal cells by increasing survival of the phagocytosed bacteria.


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