scholarly journals Drosophila melanogaster as a High-Throughput Model for Host–Microbiota Interactions

2017 ◽  
Vol 8 ◽  
Author(s):  
Mark Trinder ◽  
Brendan A. Daisley ◽  
Josh S. Dube ◽  
Gregor Reid
Keyword(s):  
Drosophila Melanogaster ◽  
High Throughput ◽  
Throughput Model

A high-throughput model for fat graft assessment

2009 ◽  
Vol 41 (10) ◽  
pp. 738-744 ◽  
Author(s):  
Miguel A. Medina ◽  
John T. Nguyen ◽  
Michael M. McCormack ◽  
Mark A. Randolph ◽  
William G. Austen
Keyword(s):  
High Throughput ◽  
Fat Graft ◽  
Throughput Model

scholarly journals Behavior Individuality: A Focus on Drosophila melanogaster

2021 ◽  
Vol 12 ◽  
Author(s):  
Rubén Mollá-Albaladejo ◽  
Juan A. Sánchez-Alcañiz
Keyword(s):  
Gene Expression ◽  
Drosophila Melanogaster ◽  
High Throughput ◽  
High Throughput Sequencing ◽  
Great Effort ◽  
Behavioral Differences ◽  
Adult Behavior ◽  
Large Numbers ◽  
Environmental Variations ◽  
And Function

Among individuals, behavioral differences result from the well-known interplay of nature and nurture. Minute differences in the genetic code can lead to differential gene expression and function, dramatically affecting developmental processes and adult behavior. Environmental factors, epigenetic modifications, and gene expression and function are responsible for generating stochastic behaviors. In the last decade, the advent of high-throughput sequencing has facilitated studying the genetic basis of behavior and individuality. We can now study the genomes of multiple individuals and infer which genetic variations might be responsible for the observed behavior. In addition, the development of high-throughput behavioral paradigms, where multiple isogenic animals can be analyzed in various environmental conditions, has again facilitated the study of the influence of genetic and environmental variations in animal personality. Mainly, Drosophila melanogaster has been the focus of a great effort to understand how inter-individual behavioral differences emerge. The possibility of using large numbers of animals, isogenic populations, and the possibility of modifying neuronal function has made it an ideal model to search for the origins of individuality. In the present review, we will focus on the recent findings that try to shed light on the emergence of individuality with a particular interest in D. melanogaster.

scholarly journals Toll‐DeficientDrosophilaFlies as a Fast, High‐Throughput Model for the Study of Antifungal Drug Efficacy against Invasive Aspergillosis andAspergillusVirulence

2005 ◽  
Vol 191 (7) ◽  
pp. 1188-1195 ◽  
Author(s):  
Michail S. Lionakis ◽  
Russell E. Lewis ◽  
Gregory S. May ◽  
Nathan P. Wiederhold ◽  
Nathaniel D. Albert ◽  
...  
Keyword(s):  
Invasive Aspergillosis ◽  
High Throughput ◽  
Drug Efficacy ◽  
Antifungal Drug ◽  
Throughput Model

Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates

2012 ◽  
Vol 32 (10) ◽  
pp. 834-842 ◽  
Author(s):  
Dingsheng Wen ◽  
Aiming Liu ◽  
Feng Chen ◽  
Julin Yang ◽  
Renke Dai
Keyword(s):  
High Throughput ◽  
Transgenic Zebrafish ◽  
Throughput Model ◽  
Toxicity Risk

MP25-09 HIGH THROUGHPUT GENETIC SCREENING WITH DROSOPHILA MELANOGASTER IDENTIFIES NOVEL GENES ASSOCIATED WITH STONE FORMATION

2014 ◽  
Vol 191 (4S) ◽  
Author(s):  
Thomas Chi ◽  
Man Su Kim ◽  
Sven Lang ◽  
Tiffany Zee ◽  
Gulinuer Muteliefu ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
High Throughput ◽  
Genetic Screening ◽  
Stone Formation ◽  
Novel Genes
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