scholarly journals Screening for Obstructive Sleep Apnea in Type 2 Diabetes Patients – Questionnaires Are Not Good Enough

2016 ◽  
Vol 7 ◽  
Author(s):  
Katerina Westlake ◽  
Jan Polak
Keyword(s):  
Type 2 Diabetes ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep ◽  
Diabetes Patients

scholarly journals Interactions between and Shared Molecular Mechanisms of Diabetic Peripheral Neuropathy and Obstructive Sleep Apnea in Type 2 Diabetes Patients

2018 ◽  
Vol 2018 ◽  
pp. 1-15 ◽  
Author(s):  
Hong Shen ◽  
Junrong Zhao ◽  
Ying Liu ◽  
Guangdong Sun
Keyword(s):  
Type 2 Diabetes ◽  
Obstructive Sleep Apnea ◽  
Peripheral Neuropathy ◽  
Sleep Apnea ◽  
Diabetic Peripheral Neuropathy ◽  
Molecular Mechanisms ◽  
Nitrosative Stress ◽  
Obstructive Sleep ◽  
Diabetes Patients

Type 2 diabetes (T2D) accounts for about 90% of all diabetes patients and incurs a heavy global public health burden. Up to 50% of T2D patients will eventually develop neuropathy as T2D progresses. Diabetic peripheral neuropathy (DPN) is a common diabetic complication and one of the main causes of increased morbidity and mortality of T2D patients. Obstructive sleep apnea (OSA) affects over 15% of the general population and is associated with a higher prevalence of T2D. Growing evidence also indicates that OSA is highly prevalent in T2D patients probably due to diabetic peripheral neuropathy. However, the interrelations among diabetic peripheral neuropathy, OSA, and T2D hitherto have not been clearly elucidated. Numerous molecular mechanisms have been documented that underlie diabetic peripheral neuropathy and OSA, including oxidative stress, inflammation, endothelin-1, vascular endothelial growth factor (VEGF), accumulation of advanced glycation end products, protein kinase C (PKC) signaling, poly ADP ribose polymerase (PARP), nitrosative stress, plasminogen activator inhibitor-1, and vitamin D deficiency. In this review, we seek to illuminate the relationships among T2D, diabetic peripheral neuropathy, and OSA and how they interact with one another. In addition, we summarize and explain the shared molecular mechanisms involved in diabetic peripheral neuropathy and OSA for further mechanistic investigations and novel therapeutic strategies for attenuating and preventing the development and progression of diabetic peripheral neuropathy and OSA in T2D.

scholarly journals Inverse Cross-sectional and Longitudinal Relationships between Diabetic Retinopathy and Obstructive Sleep Apnea in Type 2 Diabetes

2021 ◽  
Vol 1 (1) ◽  
pp. 100011
Author(s):  
Jakob Grauslund ◽  
Lonny Stokholm ◽  
Anne S. Thykjær ◽  
Sören Möller ◽  
Caroline S. Laugesen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Obstructive Sleep Apnea ◽  
Diabetic Retinopathy ◽  
Sleep Apnea ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Longitudinal Relationships

scholarly journals The effectiveness of an obstructive sleep apnea screening and treatment program in patients with type 2 diabetes

2017 ◽  
Vol 134 ◽  
pp. 145-152 ◽  
Author(s):  
Lucas M. Donovan ◽  
Michael Rueschman ◽  
Jia Weng ◽  
Nisha Basu ◽  
Katherine A. Dudley ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Treatment Program ◽  
Obstructive Sleep

scholarly journals The risk of obstructive sleep apnea among patients with type 2 diabetes mellitus

2020 ◽  
Vol 61 (1) ◽  
pp. 32
Author(s):  
VictorAniedi Umoh ◽  
EffiongEkong Akpan ◽  
UdemeEkpeyong Ekrikpo ◽  
AlphonsusUdo Idung ◽  
EyoEffiong Ekpe
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Obstructive Sleep Apnea ◽  
Type 2 Diabetes Mellitus ◽  
Sleep Apnea ◽  
Obstructive Sleep
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