scholarly journals Common Familial Effects on Ischemic Stroke and Myocardial Infarction: A Prospective Population-Based Cohort Study

2014 ◽  
Vol 1 ◽  
Author(s):  
Katherine Kasiman ◽  
Cecilia Lundholm ◽  
Sven Sandin ◽  
Ninoa Malki ◽  
Pär Sparén ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cohort Study ◽  
Ischemic Stroke ◽  
Population Based ◽  
Familial Effects

scholarly journals Relationship between blood pressure levels and ischemic stroke, myocardial infarction, and mortality in very elderly patients taking antihypertensives: a nationwide population-based cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Myung-Sun Song ◽  
Yeon joo Choi ◽  
Hyunjin Kim ◽  
Myung Ji Nam ◽  
Chung-woo Lee ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Blood Pressure ◽  
Cohort Study ◽  
Ischemic Stroke ◽  
Large Population ◽  
Antihypertensive Agents ◽  
Population Based ◽  
Very Elderly ◽  
National Health Insurance System ◽  
All Cause Mortality

Abstract Background In the very elderly, “the lower the better” hypothesis has constantly been contradicted by randomized control trials and various cohort studies, but inconsistency in results led to unclear blood pressure treatment targets. This study aimed to assess the relationship between baseline blood pressure (BP) and ischemic stroke, myocardial infarction, and all-cause mortality in very elderly people treated for hypertension. Methods This large population-based retrospective cohort study was based on the national claims database of the Korean National Health Insurance System, which covers the entire Korean population. 374,250 participants aged ≥ 75 years taking antihypertensive agents were recruited, excluding patients with a history of previous ischemic stroke or myocardial infarction. Results Systolic BP (SBP) followed a J curve for ischemic stroke and a U curve for all-cause mortality, with nadir ranges of 120 to 129 mmHg and 140 to 149 mmHg, respectively. While increasing diastolic BP (DBP) generally resulted in higher HRs for ischemic stroke, HRs for myocardial infarction and all-cause mortality significantly increased only when DBP was ≥ 80 mmHg and ≥ 90 mmHg, respectively. The SBP/DBP combination analysis showed that even with SBP < 130 mmHg, higher DBP ≥ 90 mmHg had higher HRs for all three outcomes compared to the reference group (130 to 149 / < 80 mmHg). Conclusions There were no further benefits or even harm below certain BP levels for ischemic stroke, myocardial infarction, and all-cause mortality in very elderly hypertensive patients.

scholarly journals SP372INCREASED RISK OF ISCHEMIC STROKE IN PATIENTS WITH CHRONIC KIDNEY DISEASE AFTER RECURRENT DYSNATREMIA: A NATIONWIDE POPULATION BASED COHORT STUDY IN TAIWAN

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii502-iii502
Author(s):  
Mu-Chi Chung ◽  
Tung-Min Yu ◽  
Ming-Ju Wu ◽  
Chao-Hsiang Chang ◽  
Chih-Hsin Muo ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Cohort Study ◽  
Ischemic Stroke ◽  
Kidney Disease ◽  
Population Based

scholarly journals Comorbidity and risk of venous thromboembolism after hospitalization for first‐time myocardial infarction: A population‐based cohort study

2020 ◽  
Vol 18 (8) ◽  
pp. 1974-1985
Author(s):  
Morten Würtz ◽  
Erik Lerkevang Grove ◽  
Priscila Corraini ◽  
Kasper Adelborg ◽  
Jens Sundbøll ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cohort Study ◽  
Venous Thromboembolism ◽  
Population Based ◽  
First Time

scholarly journals Acute cardiovascular events and all-cause mortality in patients with hyperthyroidism: a population-based cohort study

2017 ◽  
Vol 176 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Olaf M Dekkers ◽  
Erzsébet Horváth-Puhó ◽  
Suzanne C Cannegieter ◽  
Jan P Vandenbroucke ◽  
Henrik Toft Sørensen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cohort Study ◽  
Ischemic Stroke ◽  
Cardiovascular Events ◽  
Population Based ◽  
Arterial Embolism ◽  
Registration System ◽  
Increased Risk ◽  
All Cause Mortality

Objective Several studies have shown an increased risk for cardiovascular disease (CVD) in hyperthyroidism, but most studies have been too small to address the effect of hyperthyroidism on individual cardiovascular endpoints. Our main aim was to assess the association among hyperthyroidism, acute cardiovascular events and mortality. Design It is a nationwide population-based cohort study. Data were obtained from the Danish Civil Registration System and the Danish National Patient Registry, which covers all Danish hospitals. We compared the rate of all-cause mortality as well as venous thromboembolism (VTE), acute myocardial infarction (AMI), ischemic and non-ischemic stroke, arterial embolism, atrial fibrillation (AF) and percutaneous coronary intervention (PCI) in the two cohorts. Hazard ratios (HR) with 95% confidence intervals (95% CI) were estimated. Results The study included 85 856 hyperthyroid patients and 847 057 matched population-based controls. Mean follow-up time was 9.2 years. The HR for mortality was highest in the first 3 months after diagnosis of hyperthyroidism: 4.62, 95% CI: 4.40–4.85, and remained elevated during long-term follow-up (>3 years) (HR: 1.35, 95% CI: 1.33–1.37). The risk for all examined cardiovascular events was increased, with the highest risk in the first 3 months after hyperthyroidism diagnosis. The 3-month post-diagnosis risk was highest for atrial fibrillation (HR: 7.32, 95% CI: 6.58–8.14) and arterial embolism (HR: 6.08, 95% CI: 4.30–8.61), but the risks of VTE, AMI, ischemic and non-ischemic stroke and PCI were increased also 2- to 3-fold. Conclusions We found an increased risk for all-cause mortality and acute cardiovascular events in patients with hyperthyroidism.

scholarly journals Long-term risk of myocardial infarction and stroke in bipolar I disorder: A population-based Cohort Study

2016 ◽  
Vol 194 ◽  
pp. 120-127 ◽  
Author(s):  
Miguel L. Prieto ◽  
Louis A. Schenck ◽  
Jennifer L. Kruse ◽  
James P. Klaas ◽  
Alanna M. Chamberlain ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cohort Study ◽  
Population Based ◽  
Bipolar I Disorder

scholarly journals Women With Osteoarthritis Are at Increased Risk of Ischemic Stroke: A Population-Based Cohort Study

2021 ◽  
Author(s):  
Chung-Hsin Yeh ◽  
Wei-Lun Chang ◽  
Po-Chi Chan ◽  
Chih-Hsin Mou ◽  
Ko-Shih Chang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Ischemic Stroke ◽  
Population Based ◽  
Increased Risk

scholarly journals Incidence of myocardial infarction in elderly men being treated with antihypertensive drugs: population based cohort study

BMJ ◽  
1996 ◽  
Vol 313 (7055) ◽  
pp. 457-461 ◽  
Author(s):  
J. Merlo ◽  
J. Ranstam ◽  
H. Liedholm ◽  
B. Hedblad ◽  
G. Lindberg ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cohort Study ◽  
Antihypertensive Drugs ◽  
Population Based ◽  
Elderly Men

A population-based case-cohort study of the risk of myocardial infarction following radiation therapy for breast cancer

2007 ◽  
Vol 82 (3) ◽  
pp. 294-300 ◽  
Author(s):  
Lawrence F. Paszat ◽  
Katherine A. Vallis ◽  
Veronique M.A. Benk ◽  
Patti A. Groome ◽  
William J. Mackillop ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Myocardial Infarction ◽  
Radiation Therapy ◽  
Cohort Study ◽  
Population Based
Sign in / Sign up

Export Citation Format

Share Document