scholarly journals Serum Lipidomics Analysis of Classical Swine Fever Virus Infection in Piglets and Emerging Role of Free Fatty Acids in Virus Replication in vitro

2019 ◽  
Vol 9 ◽  
Author(s):  
Shengming Ma ◽  
Qian Mao ◽  
Wenxian Chen ◽  
Mengpo Zhao ◽  
Keke Wu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Virus Infection ◽  
Free Fatty Acids ◽  
Virus Replication ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus

scholarly journals Antiviral Role of Serine Incorporator 5 (SERINC5) Proteins in Classical Swine Fever Virus Infection

2020 ◽  
Vol 11 ◽  
Author(s):  
Wenhui Li ◽  
Zilin Zhang ◽  
Liangliang Zhang ◽  
Hong Li ◽  
Shuangqi Fan ◽  
...  
Keyword(s):  
Virus Infection ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Antiviral Role

In vitro inhibition of classical swine fever virus replication by siRNAs targeting Npro and NS5B genes

2008 ◽  
Vol 78 (3) ◽  
pp. 188-193 ◽  
Author(s):  
Xingran Xu ◽  
Huancheng Guo ◽  
Chang Xiao ◽  
Yunfeng Zha ◽  
Zixue Shi ◽  
...  
Keyword(s):  
Virus Replication ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
In Vitro Inhibition

Role of innate immunity in pathophysiology of classical swine fever virus infection

2018 ◽  
Vol 119 ◽  
pp. 248-254 ◽  
Author(s):  
Mohsan Ullah Goraya ◽  
Fozia Ziaghum ◽  
Shilong Chen ◽  
Ali Raza ◽  
Ye Chen ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Virus Infection ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus

Propagation of classical swine fever virus in vitro circumventing heparan sulfate-adaptation

2011 ◽  
Vol 176 (1-2) ◽  
pp. 85-95 ◽  
Author(s):  
Rita Eymann-Häni ◽  
Immanuel Leifer ◽  
Kenneth C. McCullough ◽  
Artur Summerfield ◽  
Nicolas Ruggli
Keyword(s):  
Heparan Sulfate ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus

scholarly journals Immunological properties of recombinant classical swine fever virus NS3 protein in vitro and in vivo

2006 ◽  
Vol 37 (1) ◽  
pp. 155-168 ◽  
Author(s):  
Henriette Rau ◽  
Hilde Revets ◽  
Carole Balmelli ◽  
Kenneth C. McCullough ◽  
Artur Summerfield
Keyword(s):  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Immunological Properties ◽  
Ns3 Protein

scholarly journals Role of African swine fever virus (ASFV) proteins EP153R and EP402R in reducing viral persistence and virulence from attenuated BeninΔDP148R

2021 ◽  
Author(s):  
Vlad Petrovan ◽  
Anusyah Rathakrishnan ◽  
Muneeb Islam ◽  
Lynnette Goatley ◽  
Katy Moffat ◽  
...  
Keyword(s):  
Virus Replication ◽  
Vaccine Development ◽  
African Swine Fever Virus ◽  
Clinical Signs ◽  
African Swine Fever ◽  
Viral Persistence ◽  
Fever Virus ◽  
Post Immunization

The limited knowledge on the role of many of the approximately 170 proteins encoded by African swine fever virus restricts progress towards vaccine development. In this study we investigated the effect of deleting combinations of different genes from a previously attenuated virus, BeninΔDP148R on: virus replication in macrophages, virus persistence and clinical signs post immunization, and induction of protection against challenge. Deletion of either EP402R or EP153R genes individually or in combination from BeninΔDP148R did not reduce virus replication in vitro. However, deletion of EP402R dramatically reduced viral persistence in vivo, whilst maintaining high levels of protection against challenge. The additional deletion of EP153R (BeninΔDP148RΔEP153RΔEP402R) further attenuated the virus and no viremia or clinical signs were observed post immunization. This was associated with decreased protection and detection of moderate levels of challenge virus in blood. Interestingly, the deletion of EP153R alone from BeninΔDP148R did not result in further virus attenuation and a slight increase in virus genome copies in blood was observed at different times post immunization when compared with BeninΔDP148R. These results show that EP402R and EP153R have a synergistic role in promoting viremia, however EP153R alone does not seem to have a major impact on virus levels in blood.

scholarly journals Complex Virus–Host Interactions Involved in the Regulation of Classical Swine Fever Virus Replication: A Minireview

Viruses ◽  
2017 ◽  
Vol 9 (7) ◽  
pp. 171 ◽  
Author(s):  
Su Li ◽  
Jinghan Wang ◽  
Qian Yang ◽  
Muhammad Naveed Anwar ◽  
Shaoxiong Yu ◽  
...  
Keyword(s):  
Virus Replication ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Host Interactions
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