scholarly journals Positive Feedback Stimulation of Ccnb1 and Mos mRNA Translation by MAPK Cascade During Mouse Oocyte Maturation

Author(s):  
Lan-Rui Cao ◽  
Jun-Chao Jiang ◽  
Heng-Yu Fan
2000 ◽  
Vol 221 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Joyce Tay ◽  
Rebecca Hodgman ◽  
Joel D. Richter

2016 ◽  
Author(s):  
Jessica Sanders ◽  
Ethan Bateson ◽  
Yuansong Yu ◽  
Michail Nomikos ◽  
Antony Lai ◽  
...  

2014 ◽  
Author(s):  
Xing Duan ◽  
Zhen-Bo Wang ◽  
Xiang-Shun Cui ◽  
Nam-Hyung Kim ◽  
Shao-Chen Sun

Cell Division ◽  
2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Ming-Hong Sun ◽  
Lin-Lin Hu ◽  
Chao-Ying Zhao ◽  
Xiang Lu ◽  
Yan-Ping Ren ◽  
...  

Abstract Background Ral family is a member of Ras-like GTPase superfamily, which includes RalA and RalB. RalA/B play important roles in many cell biological functions, including cytoskeleton dynamics, cell division, membrane transport, gene expression and signal transduction. However, whether RalA/B involve into the mammalian oocyte meiosis is still unclear. This study aimed to explore the roles of RalA/B during mouse oocyte maturation. Results Our results showed that RalA/B expressed at all stages of oocyte maturation, and they were enriched at the spindle periphery area after meiosis resumption. The injection of RalA/B siRNAs into the oocytes significantly disturbed the polar body extrusion, indicating the essential roles of RalA/B for oocyte maturation. We observed that in the RalA/B knockdown oocytes the actin filament fluorescence intensity was significantly increased at the both cortex and cytoplasm, and the chromosomes were failed to locate near the cortex, indicating that RalA/B regulate actin dynamics for spindle migration in mouse oocytes. Moreover, we also found that the Golgi apparatus distribution at the spindle periphery was disturbed after RalA/B depletion. Conclusions In summary, our results indicated that RalA/B affect actin dynamics for chromosome positioning and Golgi apparatus distribution in mouse oocytes.


PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0116783 ◽  
Author(s):  
Petr Solc ◽  
Tomoya S. Kitajima ◽  
Shuhei Yoshida ◽  
Adela Brzakova ◽  
Masako Kaido ◽  
...  

Author(s):  
Chanseob Shim ◽  
Sang Gu Lee ◽  
Woo Keun Song ◽  
Chul Sang Lee ◽  
Kyung-Kwang Lee ◽  
...  

1995 ◽  
Vol 219 (2) ◽  
pp. 414-419 ◽  
Author(s):  
J. Fulka ◽  
R.M. Moor ◽  
J. Fulka

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