scholarly journals Manfaat Emotional Freedom Technique (EFT) Bagi Pasien Dengan Gangguan Kecemasan

2020 ◽  
Vol 11 (2) ◽  
pp. 129
Author(s):  
Nurmawati S Lataima ◽  
Ninuk Dian Kurniawati ◽  
Puji Astuti
Keyword(s):  
Systematic Review ◽  
Full Text ◽  
Psychological Intervention ◽  
Improve Quality ◽  
Full Text Article ◽  
Inclusion Criteria ◽  
Stress Increase ◽  
The World ◽  
Common Problems

Background: Psychological problems such as anxiety are one of the most common problems in the world. Handling for this anxiety problem is not adequate and requires a lot of money. Psychological intervention is needed to help patients overcome the anxiety they experience. Objective: To outline some of the benefits of the Emotional Freedom Technique (EFT) intervention that can help patients reduce anxiety Method: The database used in this study was Scopus, Google Schoolar and Pubmed was limited to the last 5 years from 2015 to 2020, full text article in English. The keywords used were "Emotional Freedom Technique", "OR", "AND", "Anxiety", "AND", "Tapping". This systematic review used 11 articles that fit the inclusion criteria. Result: The EFT intervention was an easy, inexpensive and effective intervention. The benefits of the EFT intervention were reduce depression, anxiety, stress, increase immunological levels, reduce levels of cortisol in the blood and improve quality of life. Conclusion: EFT intervention has many benefits in helping patients who experience various psychological illnesses. Suggestion: EFT can be applied in health services or applied independently. Keywords: Emotional Freedom Technique; anxiety; tapping ABSTRAK Latar belakang: Masalah psikologi seperti kecemasan menjadi salah satu masalah yang paling umum di dunia. Penanganan untuk masalah kecemasan ini belum mamadai dan memerlukan biaya yang tidak sedikit. Intervensi psikologi sangat dibutuhkan untuk membantu pasien mengatasi kecemasan yang dialami. Tujuan: Untuk menguraikan beberapa manfaat intervensi EFT yang dapat membantu pasien dalam mengurangi kecemasan. Metode: Database yang digunakan dalam penelitian ini adalah Scopus, Google Schoolar dan Pubmed terbatas 5 tahun terakhir dari 2015 hingga 2020, full text article dengan berbahasa Inggris. Kata kunci yang digunakan adalah “Emotional Freedom Technique”, ”OR”, “AND”, “ Anxiety”, “AND”, “Tapping”. Systematic review ini menggunakan 11 artikel yang sesuai dengan kriteria inklusi. Hasil: EFT merupakan intervensi yang mudah, murah dan efektif. Manfaat intervensi EFT yaitu dapat menurunkan depresi, kecemasan, stress, meningkatkan kadar imunologi, menurunkan kadar kortisol dalam darah dan meningkatkan kualitas hidup. Simpulan: EFT memiliki banyak manfaat dalam membantu pasien yang mengalami berbagai penyakit psikologi. Saran: EFT dapat diterapkan dalam pelayanan kesehatan maupun diterapkan secara mandiri. Kata kunci: Emotional Freedom Technique; anxiety; tapping

scholarly journals Terapi Non Farmakalogis untuk Mengurangi Kecemasan pada Pasien Kanker dengan Kemoterapi: A Systematic Review

2020 ◽  
Vol 11 (4) ◽  
pp. 334
Author(s):  
Andrik Hermanto ◽  
Tintin Sukartini ◽  
Esti Yunitasari
Keyword(s):  
Systematic Review ◽  
Virtual Reality ◽  
Cancer Patients ◽  
Full Text ◽  
Guided Imagery ◽  
Subcutaneous Tissue ◽  
Full Text Article ◽  
Inclusion Criteria ◽  
Tissue Necrosis ◽  
Keywords Cancer

Background: Anxiety will affect the cancer patient's physiology and decrease the body's immune system, so that intervention is needed to alleviate anxiety. Objective: To find out various non-pharmacalogical therapies to reduce anxiety in cancer patients with chemotherapy. Method: The database used in this study was scopus, proquest and pubmed were limited to the last 5 years of publication from 2016 to 2020, full-text article and in english. The keywords used were "cancer" and "anxiety". This systematic review uses 10 articles that fit the inclusion criteria. Results: nonpharmacological management of cancer patients to reduce anxiety includes music therapy, autogenic training, mindfulness programs, virtual reality, guided imagery and progressive muscle training. Non-pharmacalogical therapy functions to reduce anxiety in cancer patients with chemotherapy and reduce various kinds of side effects such as anaemia, thrombocytopenia, leucopenia, nausea and vomiting, alopecia (hair loss), stomatitis, allergic reactions, neurotoxic, and extravasation (discharge of vesicle or irritant drugs to the patient) subcutaneous tissue resulting in pain, tissue necrosis, and tissue ulceration). Keywords: cancer; anxiety; nonpharmacologic therapy ABSTRAK Latar belakang: Cemas akan mempengaruhi psikologis pasien kanker dan menurunkan sistem imun tubuh, sehingga dibutuhkan intervensi yang dapat meringankan kecemasan. Tujuan: Untuk mengetahui berbagai macam terapi non farmakalogis untuk mengurangi kecemasan pada pasien kanker dengan kemoterapi. Metode: Database yang digunakan dalam studi ini adalah Scopus, Proquest dan Pubmed terbatas untuk publikasi 5 tahun terakhir dari 2016 hingga 2020, full text article dan berbahasa Inggris. Kata kunci yang digunakan adalah “cancer” AND “anxiety”. Systematic review ini menggunakan 10 artikel yang sesuai dengan kriteria inklusi Hasil: Tatalaksana nonfarmakologi pada pasien kanker untuk mengurangi cemas antara lain meliputi terapi musik, latihan autogenik, minfullnes program, virtual reality, guided imagery dan latihan otot progresif. Terapi non farmakalogis berfungsi untuk mengurangi kecemasan pada pasien kanker dengan kemoterapi dan mengurangi berbagai macam efek samping seperti anemia, trombositopenia, leucopenia, mual dan muntah, alopesia (rambut rontok), stomatitis, reaksialergi, neurotoksik, dan ekstravasasi (keluarnya obat vesikan atau iritan ke jaringan subkutan yang berakibat timbulnya rasa nyeri, nekrosis jaringan, dan ulserasi jaringan). Kata kunci: kanker; kecemasan; terapi nonfarmakologi

scholarly journals Electronic Health Interventions for Preventing and Treating Negative Psychological Sequelae Resulting From Pediatric Medical Conditions: Systematic Review (Preprint)

2018 ◽  
Author(s):  
Ashley Brook McGar ◽  
Christine Kindler ◽  
Meghan Marsac
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Full Text ◽  
Medical Conditions ◽  
Inclusion Criteria ◽  
Psychological Sequelae ◽  
Full Text Review ◽  
Electronic Health ◽  
Anxiety Depression

BACKGROUND Pediatric medical conditions have the potential to result in challenging psychological symptoms (eg, anxiety, depression, and posttraumatic stress symptoms [PTSS]) and impaired health-related quality of life in youth. Thus, effective and accessible interventions are needed to prevent and treat psychological sequelae associated with pediatric medical conditions. Electronic health (eHealth) interventions may help to meet this need, with the capacity to reach more children and families than in-person interventions. Many of these interventions are in their infancy, and we do not yet know what key components contribute to successful eHealth interventions. OBJECTIVE The primary objective of this study was to conduct a systematic review to summarize current evidence on the efficacy of eHealth interventions designed to prevent or treat psychological sequelae in youth with medical conditions. METHODS MEDLINE (PubMed) and PsycINFO databases were searched for studies published between January 1, 1998, and March 1, 2019, using predefined search terms. A total of 2 authors independently reviewed titles and abstracts of search results to determine which studies were eligible for full-text review. Reference lists of studies meeting eligibility criteria were reviewed. If the title of a reference suggested that it might be relevant for this review, the full manuscript was reviewed for inclusion. Inclusion criteria required that eligible studies (1) had conducted empirical research on the efficacy of a Web-based intervention for youth with a medical condition, (2) had included a randomized trial as part of the study method, (3) had assessed the outcomes of psychological sequelae (ie, PTSS, anxiety, depression, internalizing symptoms, or quality of life) in youth (aged 0-18 years), their caregivers, or both, (4) had included assessments at 2 or more time points, and (5) were available in English language. RESULTS A total of 1512 studies were reviewed for inclusion based on their title and abstracts; 39 articles qualified for full-text review. Moreover, 22 studies met inclusion criteria for the systematic review. Of the 22 included studies, 13 reported results indicating that eHealth interventions significantly improved at least one component of psychological sequelae in participants. Common characteristics among interventions that showed an effect included content on problem solving, education, communication, and behavior management. Studies most commonly reported on child and caregiver depression, followed by child PTSS and caregiver anxiety. CONCLUSIONS Previous research is mixed but suggests that eHealth interventions may be helpful in alleviating or preventing problematic psychological sequelae in youth with medical conditions and their caregivers. Additional research is needed to advance understanding of the most powerful intervention components and to determine when and how to best disseminate eHealth interventions, with the goal of extending the current reach of psychological interventions.

scholarly journals Factors Determining the Success and Failure of eHealth Interventions: Systematic Review of the Literature (Preprint)

2018 ◽  
Author(s):  
Conceição Granja ◽  
Wouter Janssen ◽  
Monika Alise Johansen
Keyword(s):  
Systematic Review ◽  
Quality Of Care ◽  
Qualitative Analysis ◽  
Full Text ◽  
Positive Impact ◽  
Future Research ◽  
Inclusion Criteria ◽  
Significant Discrepancy ◽  
Pubmed Database

BACKGROUND eHealth has an enormous potential to improve healthcare cost, effectiveness, and quality of care. However, there seems to be a gap between the foreseen benefits of research and clinical reality. OBJECTIVE Our objective was to systematically review the factors influencing the outcome of eHealth interventions in terms of success and failure. METHODS We searched the PubMed database for original peer-reviewed studies on implemented eHealth tools that reported on the factors for the success or failure, or both, of the intervention. We conducted the systematic review by following the patient, intervention, comparison, and outcome framework, with 2 of the authors independently reviewing the abstract and full text of the articles. We collected data using standardized forms that reflected the categorization model used in the qualitative analysis of the outcomes reported in the included articles. RESULTS Among the 903 identified articles, a total of 221 studies complied with the inclusion criteria. The studies were heterogeneous by country, type of eHealth intervention, method of implementation, and reporting perspectives. The article frequency analysis did not show a significant discrepancy between the number of reports on failure (392/844, 46.5%) and on success (452/844, 53.6%). The qualitative analysis identified 27 categories that represented the factors for success or failure of eHealth interventions. A quantitative analysis of the results revealed the category quality of healthcare (n=55) as the most mentioned as contributing to the success of eHealth interventions, and the category costs (n=42) as the most mentioned as contributing to failure. For the category with the highest unique article frequency, workflow (n=51), we conducted a full-text review. The analysis of the 23 articles that met the inclusion criteria identified 6 barriers related to workflow: workload (n=12), role definition (n=7), undermining of face-to-face communication (n=6), workflow disruption (n=6), alignment with clinical processes (n=2), and staff turnover (n=1). CONCLUSIONS The reviewed literature suggested that, to increase the likelihood of success of eHealth interventions, future research must ensure a positive impact in the quality of care, with particular attention given to improved diagnosis, clinical management, and patient-centered care. There is a critical need to perform in-depth studies of the workflow(s) that the intervention will support and to perceive the clinical processes involved.

scholarly journals Electronic Health Interventions for Preventing and Treating Negative Psychological Sequelae Resulting From Pediatric Medical Conditions: Systematic Review

10.2196/12427 ◽  
2019 ◽  
Vol 2 (2) ◽  
pp. e12427
Author(s):  
Ashley Brook McGar ◽  
Christine Kindler ◽  
Meghan Marsac
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Full Text ◽  
Medical Conditions ◽  
Inclusion Criteria ◽  
Psychological Sequelae ◽  
Full Text Review ◽  
Electronic Health ◽  
Anxiety Depression

Background Pediatric medical conditions have the potential to result in challenging psychological symptoms (eg, anxiety, depression, and posttraumatic stress symptoms [PTSS]) and impaired health-related quality of life in youth. Thus, effective and accessible interventions are needed to prevent and treat psychological sequelae associated with pediatric medical conditions. Electronic health (eHealth) interventions may help to meet this need, with the capacity to reach more children and families than in-person interventions. Many of these interventions are in their infancy, and we do not yet know what key components contribute to successful eHealth interventions. Objective The primary objective of this study was to conduct a systematic review to summarize current evidence on the efficacy of eHealth interventions designed to prevent or treat psychological sequelae in youth with medical conditions. Methods MEDLINE (PubMed) and PsycINFO databases were searched for studies published between January 1, 1998, and March 1, 2019, using predefined search terms. A total of 2 authors independently reviewed titles and abstracts of search results to determine which studies were eligible for full-text review. Reference lists of studies meeting eligibility criteria were reviewed. If the title of a reference suggested that it might be relevant for this review, the full manuscript was reviewed for inclusion. Inclusion criteria required that eligible studies (1) had conducted empirical research on the efficacy of a Web-based intervention for youth with a medical condition, (2) had included a randomized trial as part of the study method, (3) had assessed the outcomes of psychological sequelae (ie, PTSS, anxiety, depression, internalizing symptoms, or quality of life) in youth (aged 0-18 years), their caregivers, or both, (4) had included assessments at 2 or more time points, and (5) were available in English language. Results A total of 1512 studies were reviewed for inclusion based on their title and abstracts; 39 articles qualified for full-text review. Moreover, 22 studies met inclusion criteria for the systematic review. Of the 22 included studies, 13 reported results indicating that eHealth interventions significantly improved at least one component of psychological sequelae in participants. Common characteristics among interventions that showed an effect included content on problem solving, education, communication, and behavior management. Studies most commonly reported on child and caregiver depression, followed by child PTSS and caregiver anxiety. Conclusions Previous research is mixed but suggests that eHealth interventions may be helpful in alleviating or preventing problematic psychological sequelae in youth with medical conditions and their caregivers. Additional research is needed to advance understanding of the most powerful intervention components and to determine when and how to best disseminate eHealth interventions, with the goal of extending the current reach of psychological interventions.

scholarly journals Evidance Based Intervensi Psikologi Terhadap peningkatan strategi DOTS Pada Pasien Tuberkulosis: A Systematic Review

2020 ◽  
Vol 11 ◽  
pp. 74
Author(s):  
Gevi Melliya Sari ◽  
Bernadetta Germia Aridamayanti ◽  
Sariati Sariati ◽  
Dwi Uswatun Sholikhah ◽  
Cahya Mustika Narendri ◽  
...  
Keyword(s):  
Systematic Review ◽  
Patient Compliance ◽  
Full Text ◽  
Self Efficacy ◽  
Home Visit ◽  
Psychological Intervention ◽  
Tuberculosis Patient ◽  
Psychological Interventions ◽  
Full Text Article ◽  
Self Reliance

Background: Psychological problems are one of the factors that influence tuberculosis patient compliance. Psychological intervention is needed to help patients cope with stressors experienced during the treatment period of at least 6 months and increase patient compliance in undergoing treatment. Objective: To outline some of the benefits of psychological interventions that can help pulmonary tuberculosis patients follow treatment. Method: The database used in this study is Scopus, Google Scholar, and Pubmed is limited to the last 5 years of publication from 2016 to 2020, full-text article in English. The keywords used are "Psychological Intervention", "OR", "AND", "Emotional Intervention",”AND”, "Tuberculosis". This systematic review uses 9 articles that fit the inclusion criteria. Results: Psychological interventions can be applied independently or comprehensively provided with peer support, home visits, counseling, and health education. The benefits of psychological interventions can reduce depression, anxiety, stress, increase self-efficacy, improve self-reliance, increase patient knowledge, increase social support and improve patient compliance in treatment. Conclusion: Psychological intervention has many benefits in helping patients undergo a period of Tuberculosis treatment. Suggestion: Psychological intervention can be applied in health care both during patient control and home visit activities and telenursing via telephone. Keywords: emotional intervention; psychological intervention; Tuberculosis ABSTRAK Latar belakang: Masalah psikologi menjadi salah satu faktor yang mempengaruhi kepatuhan pasien Tuberkulosis. Intervensi psikologi sangat dibutuhkan untuk membantu pasien mengatasi stressor yang dialami selama masa pengobatan minimal 6 bulan serta meningkatkan kepatuhan pasien dalam menjalani masa pengobatan. Tujuan: Untuk menguraikan beberapa manfaat intervensi psikologi yang dapat membantu pasien Tuberkulosis paru dalam menjalani pengobatan Metode: Database yang digunakan dalam penelitian ini adalah Scopus, Google Schoolar dan Pubmed terbatas untuk publikasi 5 tahun terakhir dari 2016 hingga 2020, full text article dengan berbahasa Inggris. Kata kunci yang digunakan adalah “Psychological Intervention” ,”OR”, “AND”, “ Emotional Intervention”, “AND”, “Tuberculosis”. Systematic review ini menggunakan 9 artikel yang sesuai dengan kriteria inklusi. Hasil: Intervensi psikologi dapat diterapkan secara mandiri maupun diberikan secara komprehensif dengan dukungan kelompok sebaya, home visit, konseling dan pendidikan kesehatan. Manfaat intervensi psikologi yaitu dapat menurunkan depresi, kecemasan, stress, meningkatkan self efficacy, meningkatkan self reliance, meningkatkan pengetahun pasien, meningkatkan dukungan sosial dan meningkatkan kepatuhan pasien dalam menjalani pengobatan. Simpulan: Intervensi psikologi memiliki banyak manfaat dalam membantu pasien menjalani masa pengobatan Tuberkulosis. Saran: Intervensi psikologi dapat diterapkan dalam pelayanan kesehatan baik pada saat pasien kontrol maupun kegiatan kunjungan rumah dan melalui telenursing via telephone. Kata kunci: emotional intervention; psychological intervention; Tuberculosis

scholarly journals Studi Literatur: Pengaruh Hipnosis terhadap Penurunan Kecemasan pada Pasien Kanker

2020 ◽  
Vol 6 (2) ◽  
pp. 119
Author(s):  
Gandi Iswanto ◽  
Rini Rachmawaty ◽  
Julianus Ake
Keyword(s):  
Qualitative Research ◽  
Literature Review ◽  
Cancer Patients ◽  
Full Text ◽  
Research Articles ◽  
Full Text Article ◽  
Inclusion Criteria ◽  
Exclusion Criteria ◽  
Patients With Cancer ◽  
Common Problems

One of the most common problems among patients with cancer is anxiety and it can cause other physiological problems caused by anxiety. This literature review aimed to review the literature on the effect of hypnosis on reducing anxiety in cancer patients. The research design used was a literature review. The search for articles used several databases, including Pubmed, Google Scholar, with the keyword Hypnosis, Hypnosis in cancer patients, the effectiveness of hypnosis, hypnosis to lower reports. The type of article used was research articles. Collected articles were reselected based on inclusion criteria, namely: 1) The purpose of the article was to analyze the effect of hypnosis on reducing anxiety in cancer patients, 2) experimental and qualitative research. Exclusion Criteria, namely: 1) not a full text article, 2) Articles that use languages other than Indonesian and English. After searching based on keywords, we obtained 791 articles from the entire database used. Then the article selection was carried out, 6 articles were selected that met the inclusion criteria, 5 articles showed the effect of hypnosis on reducing anxiety in cancer patients, 1 article stated that hypnosis with 3 stages was more optimal for reducing anxiety, namely; self hypnosis, suggestion, visualization offers restraint. Based on the foregoing, it is concluded that hypnosis has an effect on reducing anxiety in cancer patients.

scholarly journals System models for resilience in gerontology: application to the COVID-19 pandemic

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Katarzyna Klasa ◽  
Stephanie Galaitsi ◽  
Andrew Wister ◽  
Igor Linkov
Keyword(s):  
The Elderly ◽  
System Level ◽  
Improve Quality ◽  
Care Needs ◽  
Individual Level ◽  
Chronic Stressors ◽  
The World ◽  
Aging Adults ◽  
The Individual

AbstractThe care needs for aging adults are increasing burdens on health systems around the world. Efforts minimizing risk to improve quality of life and aging have proven moderately successful, but acute shocks and chronic stressors to an individual’s systemic physical and cognitive functions may accelerate their inevitable degradations. A framework for resilience to the challenges associated with aging is required to complement on-going risk reduction policies, programs and interventions. Studies measuring resilience among the elderly at the individual level have not produced a standard methodology. Moreover, resilience measurements need to incorporate external structural and system-level factors that determine the resources that adults can access while recovering from aging-related adversities. We use the National Academies of Science conceptualization of resilience for natural disasters to frame resilience for aging adults. This enables development of a generalized theory of resilience for different individual and structural contexts and populations, including a specific application to the COVID-19 pandemic.

Acute experimentally-induced pain replicates the distribution but not the quality or behaviour of clinical appendicular musculoskeletal pain. A systematic review

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Brendon Ford ◽  
Mark Halaki ◽  
Joanna Diong ◽  
Karen A Ginn
Keyword(s):  
Systematic Review ◽  
Musculoskeletal Pain ◽  
Full Text ◽  
Experimental Pain ◽  
Common Mechanism ◽  
Mcgill Pain Questionnaire ◽  
Pain Response ◽  
Provocation Testing ◽  
Experimentally Induced

AbstractObjectivesExperimental pain is a commonly used method to draw conclusions about the motor response to clinical musculoskeletal pain. A systematic review was performed to determine if current models of acute experimental pain validly replicate the clinical experience of appendicular musculoskeletal pain with respect to the distribution and quality of pain and the pain response to provocation testing.MethodsA structured search of Medline, Scopus and Embase databases was conducted from database inception to August 2020 using the following key terms: “experimental muscle pain” OR “experimental pain” OR “pain induced” OR “induced pain” OR “muscle hyperalgesia“ OR (“Pain model” AND “muscle”). Studies in English were included if investigators induced experimental musculoskeletal pain into a limb (including the sacroiliac joint) in humans, and if they measured and reported the distribution of pain, quality of pain or response to a provocation manoeuvre performed passively or actively. Studies were excluded if they involved prolonged or delayed experimental pain, if temporomandibular, orofacial, lumbar, thoracic or cervical spine pain were investigated, if a full text of the study was not available or if they were systematic reviews. Two investigators independently screened each title and abstract and each full text paper to determine inclusion in the review. Disagreements were resolved by consensus with a third investigator.ResultsData from 57 experimental pain studies were included in this review. Forty-six of these studies reported pain distribution, 41 reported pain quality and six detailed the pain response to provocation testing. Hypertonic saline injection was the most common mechanism used to induce pain with 43 studies employing this method. The next most common methods were capsaicin injection (5 studies) and electrical stimulation, injection of acidic solution and ischaemia with three studies each. The distribution of experimental pain was similar to the area of pain reported in clinical appendicular musculoskeletal conditions. The quality of appendicular musculoskeletal pain was not replicated with the affective component of the McGill Pain Questionnaire consistently lower than that typically reported by musculoskeletal pain patients. The response to provocation testing was rarely investigated following experimental pain induction. Based on the limited available data, the increase in pain experienced in clinical populations during provocative maneuvers was not consistently replicated.ConclusionsCurrent acute experimental pain models replicate the distribution but not the quality of chronic clinical appendicular musculoskeletal pain. Limited evidence also indicates that experimentally induced acute pain does not consistently increase with tests known to provoke pain in patients with appendicular musculoskeletal pain. The results of this review question the validity of conclusions drawn from acute experimental pain studies regarding changes in muscle behaviour in response to pain in the clinical setting.

scholarly journals Medicines Related Problems (MRPs) Originating in Primary Care Settings in Older Adults - A Systematic Review

2021 ◽  
pp. 089719002110236
Author(s):  
Rosetta Chinyere Ude-Okeleke ◽  
Zoe Aslanpour ◽  
Soraya Dhillon ◽  
Nkiruka Umaru
Keyword(s):  
Systematic Review ◽  
Primary Care ◽  
Library Science ◽  
Cochrane Library ◽  
Inclusion Criteria ◽  
Data Bases ◽  
Primary Care Settings ◽  
Preventative Interventions ◽  
Use Of Health Services

Background: As people age, they become increasingly vulnerable to the untoward effects of medicines due to changes in body systems. These may result in medicines related problems (MRPs) and consequent decline or deterioration in health. Aim: To identify MRPs, indicators of deterioration associated with these MRPs, and preventative interventions from the literature. Design and Setting: Systematic review of primary studies on MRPs originating in Primary Care in older people. Methods: Relevant studies published between 2001 and April 2018 were obtained from Medline (via PubMed), CINAHL, Embase, Psych Info, PASCAL, Scopus, Cochrane Library, Science Direct, and Zetoc. Falls, delirium, pressure ulcer, hospitalization, use of health services and death were agreed indicators of deterioration. The methodological quality of included studies was assessed using the Down and Black tool. Results: There were 1858 articles retrieved from the data bases. Out of these, 21 full text articles met inclusion criteria for the review. MRPs identified were medication error, potentially inappropriate medicines, adverse drug reaction and non-adherence. These were associated with indicators of deterioration. Interventions that involved doctors, pharmacists and patients in planning and implementation yielded benefits in halting MRPs. Conclusion: This Systematic review summarizes MRPs and associated indicators of deterioration. Appropriate interventions appeared to be effective against certain MRPs and their consequences. Further studies to explore deterioration presented in this systematic review is imperative.

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