scholarly journals Oral Contraception Use in Benign Breast Tumor Patients in Dr. Soetomo General Academic Hospital

2019 ◽  
Vol 3 (12) ◽  
pp. 467-470
Author(s):  
Ayu Maghfira Nida Putri ◽  
Sjahjenny Mustokoweni ◽  
Ernawati Ernawati
Keyword(s):  
Breast Tumor ◽  
Average Length ◽  
Hormonal Contraception ◽  
Breast Tumors ◽  
Oral Contraception ◽  
Benign Tumors ◽  
Academic Hospital ◽  
Benign Breast Tumor ◽  
Contraception Use ◽  
Benign Breast Tumors

The growth of breast tumors is influenced by estrogen and progesterone hormones. One source of this hormone is hormonal contraception, including oral contraception which still in demand by Indonesian women. This study wants to identify oral contraception use in patients with benign breast tumors. This used descriptive study with a retrospective cross-sectional design. Samples were taken using the total sampling method in patients with benign breast tumors according to ICD 10 D-24 which was confirmed by FNAB examination at the POSA Dr. Soetomo General Academic Hospital between 2015-2017. Fifty three case of benign breast tumor were found with dominant characteristics at the age of group 40-49 years old (47.2%), had a breastfeeding history (50.9%), multiparous woman(64.2%), mean of menarche age at 13.28 years old and fertile periode women (83.0%). The most common type of benign tumors found were fibrocystic change. Patients who used oral contraceptives were 24.5% with an average length of use for 8 years 2 months, while another 75.5% used non-hormonal contraception or did not use any contraception. So the conclusion is majority of patients with benign breast tumors do not use oral contraception. Keywords: benign breast tumor; oral contraception; estrogen

scholarly journals Sex Steroid Hormones in Serum and Tissue of Benign and Malignant Breast Tumor Patients

2000 ◽  
Vol 16 (3-4) ◽  
pp. 151-157 ◽  
Author(s):  
Essam A. Mady ◽  
Ezz El-Din H. Ramadan ◽  
Alaa A. Ossman
Keyword(s):  
Breast Cancer ◽  
Postmenopausal Women ◽  
Steroid Hormones ◽  
Breast Tumor ◽  
Tumor Tissue ◽  
Breast Tumors ◽  
Sex Steroid ◽  
Malignant Breast Tumor ◽  
Malignant Breast ◽  
Benign Breast Tumors

The ability of breast tumors to synthesize sex steroid hormones is well recognized and their local production is thought to play a role in breast cancer development and growth. The aim of this study was to estimate local intra-tumoral and circulating levels of Estrone (E1), Estrone Sulfate (E1S), Estradiol (E2), Estriol (E3), and Testosterone (T) in 33 pre- and postmenopausal women with primary breast cancer in comparison to 12 pre- and postmenopausal women with benign breast tumors. The mean levels of the studied sex hormones were higher in serum and tumor tissue of breast cancer women than those with benign breast tumors apart from Testosterone which showed a significant decrease in pre- and postmenopausal women with breast cancer (P< 0.001 for follicular phase,P< 0.001 for luteal phase, andP< 0.001 for postmenopausal). The levels of the five hormones were significantly higher intra-tumoral than in serum of both benign and malignant breast tumor women with E1S as the predominant estrogen. There was only a positive significant correlation between serum and tumor tissue levels of E1(rs= 0.52,P< 0.05 for follicular;rs= 0.63,P< 0.05 for luteal andrs= 0.58,P< 0.05 for postmenopausal) and a significant correlation between serum and tumor tissue of T (rs= 0.64,P< 0.05 for follicular;rs= -0.51,P< 0.05 for luteal andrs= -0.81,P< 0.04 for postmenopausal).

scholarly journals Hormonal contraception increases risk of breast tumor based on clinical breast examination among adult women

2017 ◽  
Vol 36 (2) ◽  
pp. 138
Author(s):  
Sulistyowati Tuminah Darjoko ◽  
Aprildah Nur Sapardin
Keyword(s):  
Breast Cancer ◽  
Total Cholesterol ◽  
Breast Tumor ◽  
Hormonal Contraception ◽  
Clinical Breast Examination ◽  
Adult Women ◽  
Breast Examination ◽  
Contraception Use ◽  
Clinical Breast ◽  
Advanced Analysis

<p>Background<br />In Indonesia, cancer prevalence according to the Basic Health Research 2013 was 1.4 per 1000 inhabitants and the most common cancer in hospitalized patients in 2010 was breast cancer (28.7%). Hormonal contraception (HC) use increases the breast cancer risk, even though HC has been used by 210 million women in the world. We aimed to define the association of HC with breast tumors based on clinical breast examination (CBE).</p><p>Methods<br />A case-control design using secondary data from the baseline of the Cohort Study on the Risk Factors of Non-Communicable Disease (RFNCD) in 2011-2012 in 5 villages in Central Bogor District, Bogor City. Samples consisted of 152 cases and 152 controls. Cases comprised palpable tumors in one or both breasts CBE (+). Controls had no tumors in both breasts /CBE(-). Data were analyzed by logistic regression.</p><p>Results<br />Odds Ratio (OR) of CBE + was 1.83 (95% CI: 1.11-3.04; p=0.019) for HC user and 1.62 (95% CI: 1.01-2.60; p=0.044) for blood total cholesterol level &lt;200 mg/dL. OR of group CBE(+) was 1.01 (current smoking) and 0.49 (former smoking) compared with nonsmoking (p=0.082); OR was also 1.21 for subjects with one child and 1.77 for those without children, compared with those who had ³2 children (p=0.454).</p><p>Conclusion <br />Hormonal contraception use increases breast tumor risk 1.8-fold after controlling for total cholesterol, smoking status and parity. With the several limitations of this advanced analysis, investigations focused on types and duration of HC use are still necessary.</p>

scholarly journals The role of Ghrelin Receptor Expression in the Diagnosis of breast cancer

2020 ◽  
Vol 11 (2) ◽  
pp. 1438-1446
Author(s):  
Abbas M. Ajeed ◽  
Alaa G. Hussein ◽  
Nazar Alwakeel ◽  
Omar F. Abdul-Rasheed
Keyword(s):  
Breast Cancer ◽  
Breast Tumor ◽  
Breast Tumors ◽  
Receptor Expression ◽  
Tissue Samples ◽  
Ghrelin Receptor ◽  
Female Patients ◽  
Benign Breast Tumor ◽  
Tumor Tissues

To determine the possible role of the assessment of Ghrelin receptor expression in breast tissues as a tool for the diagnosis of breast cancer and differentiate it from a benign breast tumor. A case-control study was done on 60 female patients with breast cancer and 60 female patients with benign breast tumors (Fibroadenoma) who were recruited from Al Imamain Al-Kadhemain Medical City and Oncology teaching Hospital, Baghdad, Iraq between May 2018 and December 2018. Immunohistochemical staining was done on the breast tissue samples obtained from patients and compared with the control group, which comprised 75 fibrocystic tissue samples obtained from age, BMI and sex-matched females. The degree of Ghrelin Receptor expression was determined immunohistochemically. The expression of Ghrelin receptors in breast malignant tumor tissues was higher than that in benign breast tumor tissues and controls, in addition to that, results obtained from all groups revealed that Ghrelin receptor intensity and its expression proportion were strongly and significantly associated with the type of tissues. The expression of the Ghrelin receptor can be considered as a highly significant immunohistochemical marker for the detection of breast tumors and for the differentiation between both types of tumors; benign and malignant.

scholarly journals Patient Satisfaction in the Complete Removal of Giant Breast Fibroadenoma under Vacuum-Associated Breast Biopsy Procedure

2021 ◽  
Vol 9 (C) ◽  
pp. 40-42
Author(s):  
Monica Bellynda ◽  
Kristanto Yuli Yarso
Keyword(s):  
Breast Biopsy ◽  
Ultrasound Examination ◽  
Benign Lesion ◽  
Complete Removal ◽  
Breast Tumors ◽  
Benign Tumors ◽  
Breast Fibroadenoma ◽  
Biopsy Examination ◽  
The Right ◽  
Benign Breast Tumors

INTRODUCTION: Fibroadenomas are one of the most common benign tumors of the breast in the adolescent population. They account for 68% of all breast masses and 44–94% of all biopsied breast lesions. Fibroadenomas can range from asymptomatic masses to painful and rapidly growing tumors that can cause significant esthetic distortions of the breast. With breast examinations becoming common in women as young as their 20s, excision of benign breast tumors using vacuum-assisted breast biopsy (VABB) became more common. The VABB procedure with ultrasound guiding is still used for removal benign breast tumors. CASE REPORT: A 24-year ago woman presents with complaints of a lump in the right breast for 3 years, the lump is slow growing. The mass diameter is about 6 cm and no ulcers. Ultrasound examination found a solid mass, firm boundaries, regular contours, mobile in the outer quadrant of the right breast, no specific microcalcification size 6.13 cm × 3.11 cm × 5.33 cm (BIRADS 4a). Core biopsy examination showed fibroadenoma mammae intracanalicular and pericanalicular. We used an 8G needle and got 458 slices about 100 g. After the procedure, a total removal is obtained by ultrasound examination from a previously existing mass of 6 cm. CONCLUSIONS: The VABB procedure is very effective and efficient in removing breast fibroadenoma (benign lesion) and the results are satisfactory. The advantage of this procedure apart from the cosmetic aspect which does not leave any marks is also a high level of safety. From our case, we can take complete removal with a diameter of 6 cm, whereas in the previous literature, it can only remove a mass of 3–4 cm in size.

Genital abnormalities, hormonal contraception, and HIV transmission risk in Rwandan serodifferent couples

2021 ◽  
Author(s):  
Kristin M Wall ◽  
Etienne Karita ◽  
Julien Nyombayire ◽  
Rosine Ingabire ◽  
Jeannine Mukamuyango ◽  
...  
Keyword(s):  
Hiv Transmission ◽  
Hormonal Contraception ◽  
Male Partner ◽  
Female Partner ◽  
Transmission Risk ◽  
Hiv Positive ◽  
Genital Ulceration ◽  
Factors Associated ◽  
Contraception Use ◽  
Hiv Acquisition

Abstract Background We explored the role of genital abnormalities and hormonal contraception in HIV transmission among heterosexual serodifferent couples in Rwanda. Methods From 2002-2011, non-antiretroviral treatment using HIV serodifferent couples were followed and sociodemographic and clinical data were collected, family planning provided, and HIV-negative partners retested. Couples were assessed for genital ulcers; non-ulcerative genital sexually transmitted infection (STI) including gonorrhea, chlamydia, and trichomoniasis; and non-STI vaginal infections including bacterial vaginosis and candida. Multivariable models evaluated associations between covariates and HIV transmission genetically linked to the index partner. Results Among 877 couples where the man was HIV-positive, 37 linked transmissions occurred. Factors associated with women’s HIV acquisition included female partner genital ulceration (adjusted hazard ratio [aHR]=14.1) and male partner non-ulcerative STI (aHR=8.6). Among 955 couples where the woman was HIV-positive, 46 linked transmissions occurred. Factors associated with men’s HIV acquisition included female partner non-ulcerative STI (aHR=4.4), non-STI vaginal dysbiosis (aHR=7.1), and male partner genital ulceration (aHR=2.6). Hormonal contraception use was not associated with HIV transmission or acquisition. Conclusions Our findings underscore the need for integrating HIV services with care for genital abnormalities. Barriers (e.g., cost for training, demand creation, advocacy, client education; provider time; clinic space) to joint HIV/STI testing need to be considered and addressed.

Capillary Hemangioma of the Breast-a Rare Type of benign Breast Tumor

2015 ◽  
Vol 22 (3) ◽  
pp. 355-356 ◽  
Author(s):  
Wei Ma ◽  
Feng Jin ◽  
Yunfei Wu
Keyword(s):  
Breast Tumor ◽  
Capillary Hemangioma ◽  
Rare Type ◽  
Benign Breast Tumor

Serum Phospholipid Fatty Acids in Benign Breast Tumor and Breast Cancer

2009 ◽  
Vol 42 (3) ◽  
pp. 213
Author(s):  
Eugene Shim ◽  
Sei Hyun Ahn ◽  
You-Jeong Hwang ◽  
Yang Cha Lee-Kim
Keyword(s):  
Breast Cancer ◽  
Fatty Acids ◽  
Breast Tumor ◽  
Phospholipid Fatty Acids ◽  
Serum Phospholipid ◽  
Benign Breast Tumor

Effect of extended oral contraception use on the prevalence of fetal trisomy 21 in women aged at least 35 years

2017 ◽  
Vol 138 (3) ◽  
pp. 261-266 ◽  
Author(s):  
Dániel Horányi ◽  
Lilla Éva Babay ◽  
János Rigó ◽  
Balázs Győrffy ◽  
Gyula R. Nagy
Keyword(s):  
Trisomy 21 ◽  
Oral Contraception ◽  
Contraception Use
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