scholarly journals Dietary Biotin Effects on Polyunsaturated Fatty Acids in Chick Tissue Lipids and Prostaglandin E2 Levels in Freeze-Clamped Hearts

1987 ◽  
Vol 66 (11) ◽  
pp. 1818-1828 ◽  
Author(s):  
B.A. WATKINS ◽  
F.H. KRATZER
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Prostaglandin E2 ◽  
Tissue Lipids ◽  
Chick Tissue

Uptake and interconversion of plasma unesterified n-3 polyunsaturated fatty acids by the GI tract of rats

1995 ◽  
Vol 268 (5) ◽  
pp. G732-G738
Author(s):  
A. Nilsson ◽  
W. Becker
Keyword(s):  
Fatty Acids ◽  
Small Intestine ◽  
Gastrointestinal Tract ◽  
Docosahexaenoic Acid ◽  
Polyunsaturated Fatty Acids ◽  
Gi Tract ◽  
Tissue Lipids ◽  
Blood Albumin

The origin of the linoleic [18:2(n-6)], arachidonic [20:4(n-6)], and docosahexaenoic acid [22:6(n-3)] of the mucosal phospholipids in the gastrointestinal (GI) tract is not known. This study examines whether stomach, small intestine, and colon take up and desaturate-elongate unesterified polyunsaturated fatty acids (PUFA) from blood. Albumin-bound unesterified alpha-[14C]linolenate [18:3(n-3)] and [3H]eicosapentaenoate [20:5(n-3)] were injected intravenously. After 10 min, 1 h, and 18 h, radioactivity of tissue lipids and the degree of interconversion of the 3H-labeled and 14C-labeled fatty acids were determined. After 10 min, the lipids of the gastrointestinal tract contained 3.6% of the 14C (0.5% in stomach, 2.7% in small intestine, and 0.4% in colon) and 4.9% of the 3H (0.6% in stomach, 3.6% in small intestine, and 0.7% in colon). Both fatty acids were acylated mainly into phospholipids, both in liver and gastrointestinal tract. Although the proportions of radioactivity found in desaturation-elongation products increased with time, 15% of the 14C in the liver, 6% in the stomach, 8% in the small intestine, and 11% in the colon were in 20:5 already after 10 min. A rapid interconversion of 18:3 thus occurred both in the liver and in the gastrointestinal tract. In all tissues examined, interconversion of [3H]20:5 to [3H]22:5 also occurred. Interconversion of unesterified PUFA taken up from blood may be an important source of eicosanoid precursors in the gastrointestinal tract.

Time course of incorporation of n-3 PUFA from linseed in pigs and effects on D9-desaturase activity and pork odours

2001 ◽  
Vol 2001 ◽  
pp. 71-71
Author(s):  
M. Kouba ◽  
M. Enser ◽  
G.R. Nute ◽  
F.M. Whittington ◽  
J.D. Wood ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Polyunsaturated Fatty Acids ◽  
Time Course ◽  
Desaturase Activity ◽  
Monounsaturated Fatty Acids ◽  
Lipid Classes ◽  
Inhibitory Effects ◽  
Tissue Lipids ◽  
Feeding Sources

The n-3 polyunsaturated fatty acids (PUFA) are healthy nutrients which can be increased in pork by feeding sources such as linseed to the growing animal. The levels achieved depend on many factors such as the concentrations of lipid classes in tissues (eg phospholipids containing high PUFA levels are more abundant in muscle than adipose tissue) competition for incorporation with n-6 PUFA and possible inhibitory effects of PUFA on synthesis of saturated and monounsaturated fatty acids. This study examined the time course of the incorporation of n-3 PUFA into tissue lipids and the effects on the major synthetic enzyme D9-desaturase. The effects on pork odour were also studied.

scholarly journals Targets and procedures for altering ruminant meat and milk lipids

1999 ◽  
Vol 58 (3) ◽  
pp. 593-607 ◽  
Author(s):  
D. Demeyer ◽  
M. Doreau
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Milk Fat ◽  
Lipid Fraction ◽  
Conjugated Linoleic Acids ◽  
Fat Depots ◽  
Tissue Lipids ◽  
Ruminant Meat

Beef and dairy products suffer from a negative health image, related to the nature of their lipid fraction. Rumen lipid metabolism involves the presence of saturated lipids in ruminant tissues. Lipolysis, fatty acid biohydrogenation and formation of microbial fatty acids in the rumen and their effects on rumen outflow of fatty acids are discussed. Special emphasis is given to the formation of trans-fatty acids and the possibilities of decreasing biohydrogenation. Small differences in intestinal digestibilities of fatty acids are mentioned, followed by a discussion on transfer of absorbed fatty acids into milk and adipose tissue lipids. The preferential retention of polyunsaturated fatty acids as well as the balance between synthesis and incorporation of fatty acids in tissues is described. Dietary means for the modification of milk fat are listed, with special emphasis on the possibilities for enrichment in polyunsaturated fatty acids and the presence of conjugated linoleic acids. A description of the nature and development of fat depots in beef cattle is followed by a discussion of breed, conformation and feed effects on adipose tissue distribution and fatty acid composition. Special emphasis is given to the very lean Belgian Blue double-muscled breed. The review ends with a consideration of the limits to the modification of ruminant fats, involving considerations of consumer acceptance as well as animal welfare and environmental effects.

Polyunsaturated fatty acids regulate cytokine and prostaglandin E2 production by respiratory cells in response to mast cell mediators

Lipids ◽  
2006 ◽  
Vol 41 (12) ◽  
pp. 1101-1107 ◽  
Author(s):  
Dani-Louise Bryan ◽  
Kevin D. Forsyth ◽  
Prue H. Hart ◽  
Robert A Gibson
Keyword(s):  
Fatty Acids ◽  
Mast Cell ◽  
Polyunsaturated Fatty Acids ◽  
Prostaglandin E2 ◽  
Respiratory Cells
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