scholarly journals Comparative Effects of Sodium Selenite and Selenomethionine upon Nutritional Muscular Dystrophy, Selenium-Dependent Glutathione Peroxidase, and Tissue Selenium Concentrations of Turkey Poults

1982 ◽  
Vol 61 (3) ◽  
pp. 478-484 ◽  
Author(s):  
AUSTIN H. CANTOR ◽  
PHILIP D. MOORHEAD ◽  
MARGERY A. MUSSER
Keyword(s):  
Muscular Dystrophy ◽  
Glutathione Peroxidase ◽  
Sodium Selenite ◽  
Turkey Poults ◽  
Tissue Selenium ◽  
Nutritional Muscular Dystrophy

Some aspects of selenium metabolism in sheep

1961 ◽  
Vol 12 (5) ◽  
pp. 927 ◽  
Author(s):  
FB Cousins ◽  
IM Cairney
Keyword(s):  
Muscular Dystrophy ◽  
Sodium Selenite ◽  
White Muscle ◽  
Selenium Status ◽  
Faecal Excretion ◽  
Selenium Metabolism ◽  
Tissue Levels ◽  
Tissue Selenium ◽  
Low Levels ◽  
Relationship Of

The occurrence and relationship of various complaints in lambs and hoggets, preventable by selenium prophylaxis, are reviewed. The excretion and tissue retention of selenium by animals on normal feeds and on oral dosing with sodium selenite are given. Faecal excretion of selenium, even on low levels of intake, is high and it is suggested that reduction of dietary selenium to a non-available form occurs in the rumen. In all animals investigated, the kidney showed the highest selenium levels and was the organ most influenced by selenium absorption. The kidney selenium levels provide an adequate index of the animal's selenium status. Tissue selenium levels from healthy, white muscle, and ill-thrifty lambs and hoggets were investigated. There is evidence that the occurrence of muscular dystrophy in lambs, but not necessarily in hoggets, is related to lowered tissue levels of selenium. Findings with respect to ill-thrift and selenium tissue levels were equivocal. The above work is considered together with published information on the nutritional causes of muscular dystrophy in sheep.

scholarly journals Changes of selected biochemical indicators and electrocardiography indicators in nutritional muscular dystrophy in calves

2012 ◽  
Vol 81 (2) ◽  
pp. 119-125 ◽  
Author(s):  
Katarzyna Żarczyńska ◽  
Przemysław Sobiech ◽  
Andrzej Pomianowski ◽  
Agata Waclawska-Matyjasik ◽  
Artur Stopyra ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Vitamin E ◽  
Lactate Dehydrogenase ◽  
Muscular Dystrophy ◽  
Glutathione Peroxidase ◽  
Wave Amplitude ◽  
Blood Samples ◽  
Biochemical Indicators ◽  
T Wave ◽  
Nutritional Muscular Dystrophy

The aim of this study was to estimate changes in selected biochemical indicators during nutritional muscular dystrophy of calves and to use electrocardiography technique in early diagnosis of this disease. The study was performed on 24 Holstein-Friesian calves of both sexes, divided into two groups. The first one was experimental group of 12 calves with symptoms of nutritional muscular dystrophy and the second one was control group of 12 clinically healthy calves administered a single i.m. injection of vitamin E + selenium preparation on the second day after birth. Blood samples were collected from all animals 3 × at 7-day intervals, starting on day 5. Blood serum was subjected to biochemical analyses to determine Se and vitamin E concentrations, aspartate aminotransferase, creatine kinase and lactate dehydrogenase activity levels. The activity of glutathione peroxidase was determined in whole blood samples. Electrocardiographic assessment was performed on day 19 in all calves. In the group of calves with symptoms of nutritional muscular dystrophy, serum Se and vitamin E concentrations were significantly (P ≤ 0.01) lower than in control, the same was true for the activity of glutathione peroxidase (P ≤ 0.01). The changes were accompanied by an increase (P ≤ 0.01) in the activity of aspartate aminotransferase, creatine kinase and lactate dehydrogenase. The electrocardiograms of experimental animals revealed elevated heart rate, accelerated sinus rhythm, increased P wave amplitude, shorter PR, QT and ST interval, narrower QRS complex, shorter T wave duration and insignificantly increased T wave amplitude; these results were indicative of arrhythmia which is observed at early stages of cardiomyopathy. This study is the first one in which electrocardiography technique was used to diagnose nutritional muscular dystrophy in calves.

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