Subjective Measurements of In-Flight Sleep, Circadian Variation, and Their Relationship with Fatigue

2016 ◽  
Vol 87 (10) ◽  
pp. 869-875 ◽  
Author(s):  
Margo J. van den Berg ◽  
Lora J. Wu ◽  
Philippa H. Gander
Keyword(s):  
Circadian Variation ◽  
Subjective Measurements

Circadian Variation of Paroxysmal Atrial Fibrillation

Circulation ◽  
1997 ◽  
Vol 96 (5) ◽  
pp. 1537-1541 ◽  
Author(s):  
Takeshi Yamashita ◽  
Yuji Murakawa ◽  
Kazunori Sezaki ◽  
Masashi Inoue ◽  
Noriyuki Hayami ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Paroxysmal Atrial Fibrillation ◽  
Circadian Variation

scholarly journals Distinct regulation of hippocampal neuroplasticity and ciliary genes by corticosteroid receptors

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Karen R. Mifsud ◽  
Clare L. M. Kennedy ◽  
Silvia Salatino ◽  
Eshita Sharma ◽  
Emily M. Price ◽  
...  
Keyword(s):  
Dna Sequences ◽  
Glucocorticoid Receptors ◽  
Acute Stress ◽  
Circadian Variation ◽  
Rna Seq ◽  
Physiological Regulation ◽  
Behavioural Adaptation ◽  
Neuronal Progenitor ◽  
Genome Wide ◽  
Transcriptional Changes

AbstractGlucocorticoid hormones (GCs) — acting through hippocampal mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) — are critical to physiological regulation and behavioural adaptation. We conducted genome-wide MR and GR ChIP-seq and Ribo-Zero RNA-seq studies on rat hippocampus to elucidate MR- and GR-regulated genes under circadian variation or acute stress. In a subset of genes, these physiological conditions resulted in enhanced MR and/or GR binding to DNA sequences and associated transcriptional changes. Binding of MR at a substantial number of sites however remained unchanged. MR and GR binding occur at overlapping as well as distinct loci. Moreover, although the GC response element (GRE) was the predominant motif, the transcription factor recognition site composition within MR and GR binding peaks show marked differences. Pathway analysis uncovered that MR and GR regulate a substantial number of genes involved in synaptic/neuro-plasticity, cell morphology and development, behavior, and neuropsychiatric disorders. We find that MR, not GR, is the predominant receptor binding to >50 ciliary genes; and that MR function is linked to neuronal differentiation and ciliogenesis in human fetal neuronal progenitor cells. These results show that hippocampal MRs and GRs constitutively and dynamically regulate genomic activities underpinning neuronal plasticity and behavioral adaptation to changing environments.

scholarly journals Back-Support Exoskeleton Control Strategy for Pulling Activities: Design and Preliminary Evaluation

Designs ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 39
Author(s):  
Maria Lazzaroni ◽  
Tommaso Poliero ◽  
Matteo Sposito ◽  
Stefano Toxiri ◽  
Darwin G. Caldwell ◽  
...  
Keyword(s):  
Control Strategy ◽  
Muscle Activity ◽  
Material Handling ◽  
Ease Of Use ◽  
Biomechanical Analysis ◽  
Perceived Support ◽  
Preliminary Evaluation ◽  
Subjective Measurements ◽  
Spinal Muscles ◽  
Forearm Muscle

The execution of manual material handling activities in the workplace exposes workers to large lumbar loads that increase the risk of musculoskeletal disorders and low back pain. In particular, the redesign of the workplace is making the execution of pulling activities more common, as an alternative to lifting and carrying tasks. The biomechanical analysis of the task revealed a substantial activation of the spinal muscles. This suggests that the user may benefit from the assistance of a back-support exoskeleton that reduces the spinal muscle activity and their contribution to lumbar compression. This work addresses this challenge by exploiting the versatility of an active back-support exoskeleton. A control strategy was specifically designed for assisting pulling that modulates the assistive torques using the forearm muscle activity. These torques are expected to adapt to the user’s assistance needs and the pulled object mass, as forearm muscle activity is considered an indicator of grip strength. We devised laboratory experiments to assess the feasibility and effectiveness of the proposed strategy. We found that, for the majority of the subjects, back muscle activity reductions were associated with the exoskeleton use. Furthermore, subjective measurements reveal advantages in terms of perceived support, comfort, ease of use, and intuitiveness.

scholarly journals B-PO05-193 UNIQUE CIRCADIAN VARIATION OF SUDDEN CARDIAC DEATH IN THE YOUNG

Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S450
Author(s):  
Faye L. Norby ◽  
Harpriya Chugh ◽  
Arayik Sargsyan ◽  
Audrey Uy-Evanado ◽  
Jonathan Jui ◽  
...  
Keyword(s):  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Circadian Variation

Hyaluronic Acid Fillers for Midface Augmentation: A Systematic Review

2021 ◽  
Author(s):  
Lily N. Trinh ◽  
Amar Gupta
Keyword(s):  
Systematic Review ◽  
Hyaluronic Acid ◽  
Subcutaneous Tissue ◽  
Age Groups ◽  
Medical Subject Headings ◽  
Mesh Terms ◽  
Full Text Review ◽  
Filler Injections ◽  
Subjective Measurements ◽  
Meta Analyses

AbstractInjectable fillers represent one of the most requested minimally invasive treatments to rejuvenate the aging face, and its popularity is steadily rising. A vast majority of filler treatments are with hyaluronic acid (HA). The aim of this systematic review is to evaluate patient outcomes, safety profile, and administration techniques of various HA fillers for malar augmentation. A systematic review of the published literature was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and included PubMed, Embase, and Science Direct databases. Medical Subject Headings (MeSH) terms used were “cheek” OR “midface” OR “malar” and “filler” OR “hyaluronic acid” OR “Juvederm” OR “Restylane” OR “Perlane” OR “Belotero.” The initial search identified 699 articles; 256 duplicates were removed. Additional 12 studies were identified from reference lists. A total of 455 were screened by title and abstract and 387 studies were eliminated based on criteria. Also, 68 articles underwent full-text review, and 18 articles were included in the final review and involved seven different HA formulations. Men and women from many age groups were highly satisfied with their results following HA treatment for midface augmentation up to 24 months. The most common adverse events included bruising, swelling, and tenderness, and typically lasted no more than 2 weeks. Upper cheek filler injections near the zygoma should be placed in the submuscular plane while lower cheek injections should be placed in the subcutaneous tissue. HA is an attractive choice for midface augmentation due to its high patient satisfaction, long-lasting effects, and low side-effect profile. Due to the variability in technique, level of expertise, and subjective measurements across studies, one optimal regimen could not be concluded. However, midface augmentation treatment should be personalized to each patient. Additional clinical trials are required to more conclusively determine the most appropriate approach for this procedure.

Possible circadian variation of serum mast cell tryptase concentration

Allergy ◽  
2005 ◽  
Vol 60 (5) ◽  
pp. 689-692 ◽  
Author(s):  
S. Dugas-Breit ◽  
B. Przybilla ◽  
P. Schopf ◽  
F. Rueff
Keyword(s):  
Mast Cell ◽  
Circadian Variation ◽  
Mast Cell Tryptase

scholarly journals Circadian Variation of the Onset of Acute Myocardial Infarction in the Osaka Area, 1998-1999

2001 ◽  
Vol 65 (7) ◽  
pp. 617-620 ◽  
Author(s):  
Kunihiro Kinjo ◽  
Hideyuki Sato ◽  
Hiroshi Sato ◽  
Issei Shiotani ◽  
Toshiya Kurotobi ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Circadian Variation
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