scholarly journals Effect of Sex Hormones on Plasma Phospholipid Fatty Acid Composition in Intact Rats and Rats With Bilaterally Occluded Carotid Arteries

2014 ◽  
pp. 331-339
Author(s):  
S. PETROVIĆ ◽  
M. TAKIĆ ◽  
A. ARSIĆ ◽  
V. VUČIĆ ◽  
D. DRAKULIĆ ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Carotid Arteries ◽  
Plasma Lipids ◽  
Phospholipid Fatty Acid ◽  
Plasma Phospholipid ◽  
Phospholipid Fatty Acid Composition ◽  
Estradiol Treatment ◽  
Total N

The effects of 8-days treatment with 17α-estradiol (33.3 µg/kg) and progesterone (1.7 mg/kg) on plasma lipids and fatty acid composition of plasma phospholipids were examined in intact (INT) and bilaterally common carotid arteries occluded (BCO) male Wistar rats. Significant decrease of triglyceride level was found in BCO rats after the estradiol treatment. Both hormones elevated proportion of 18:1n-7 fatty acid in INT, but they failed to have such an effect in BCO. Estradiol increased 22:5n-3 and total n-3 polyunsaturated fatty acids (PUFA) in intact, and decreased 18:2n-6 in BCO rats. Significantly lower level of total n-3 was found in progesterone-treated than in estradiol-treated BCO rats. Given that n-3 PUFA have many beneficial effects on cell and tissue function, while n-6 PUFA have mostly the opposite effects, estradiol, rather than progesterone, was seen to improve plasma lipids and phospholipids FA profiles in INT and BCO animals. Estradiol significantly elevated the estimated activity of Δ9-desaturases and progesterone of Δ5-desaturase in BCO group, with no effects in INT rats.

scholarly journals Effect of long-term strenuous training on the plasma phospholipid fatty acid composition in handball players

2020 ◽  
Vol 77 (8) ◽  
pp. 826-831 ◽  
Author(s):  
Aleksandra Arsic ◽  
Snjezana Petrovic ◽  
Nikola Cikiriz ◽  
Danijela Ristic-Medic ◽  
Vesna Vucic
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Fatty Acid Metabolism ◽  
Acid Metabolism ◽  
Phospholipid Fatty Acid ◽  
Plasma Phospholipid ◽  
Control Group ◽  
Phospholipid Fatty Acid Composition

Background/Aim. Consensus on the exercise effect on the fatty acid metabolism has not been reached, and probably depends on the type of sports (aerobic, anaerobic or mixed). The aim of this study was to investigate effect of long-term handball training on the body composition, lipid profile and the plasma phospholipid fatty acid composition in female and male younger players. Methods. Seventeen female and 15 male active handball players, aged 16?20 years, who competed at the national/international level, were enrolled in the study. A control group was established from healthy, sedentary individuals (13 females and 19 males, aged 17?21 years), comparable to the athletes in terms of age, sex and body mass index. Results. In both groups of handball players a higher percentage of palmitoleic acid and alpha linolenic acid (18:3, n-3), were found and lower percentage of oleic acid and docosahexaenoic acid (22:6, n-3), when compared with corresponding control group. On the other hand, the lower level of stearic acid and estimated activity of plasma elongase was detected in female players than in sedentary women. Furthermore, higher proportion of linoleic acid (18:2, n-6), n-6 polyunsaturated fatty acids (PUFA) and total PUFA was found only in female players in comparison to the control group. Conclusion. The observed differences between handball players and sedentary individuals showed that handball training influenced lipid and fatty acid metabolism. Follow-up of these changes could indicate potential need for supplementation or nutritional intervention in young handball players.

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