Finding the Molecular Fingerprint of Psychological Resilience in Breast Cancer Patients

2020 ◽  
Author(s):  
Carl Borrebaeck ◽  
Ulrika Axelsson
2019 ◽  
Vol 1 ◽  
pp. 98-104
Author(s):  
EC. Fradelos

<br/><b>Introduction:</b> Death anxiety, fear of abundance, isolation, stigma of the disease and medication side effects are among the most common sources of anxiety and depression in patients with breast cancer. <br/><b>Purpose:</b> To examine the possible relationship between religiosity, psychological resilience and depression on breast cancer patients. <br/><b>Materials and methods:</b> A cross-sectional design was employed in this study which 152 breast cancer patients participated. Data were collected with the following instruments: Patient Health Questionnaire-2-item scale, Connor-Davidson Resilience Scale 25 and Centrality of Religiosity Scale and a special designed sheet reporting social, demographic and clinical characteristics. Statistical analyses were conducted with the Statistical Package for the Social Science V25. Descriptive statistics such means, and frequencies were calculated and inferential statistics such correlation test, simple and multiple regression analysis were applied. <br/><b>Results:</b> Approximately 1 in 3 patients suffered symptoms of depression while they were reporting moderate religiosity and resilience values. Based on the four-step mediation analysis religiosity was strongly associated with psychological resilience but it was not found to affect directly either depression, but psychological resilience can be a mediator between religiosity and depression. <br/><b>Conclusion:</b> This study supports the notion thatreligiosity and spirituality can have a beneficial influence on health outcomes.


2015 ◽  
Vol 3 (4) ◽  
pp. 727-731 ◽  
Author(s):  
Gordana Ristevska-Dimitrоvska ◽  
Izabela Filov ◽  
Domnika Rajchanovska ◽  
Petar Stefanovski ◽  
Beti Dejanova

BACKGROUND: Many studies have shown that a relationship exists between quality of life (QoL) and resilience in breast cancer patients, but few studies present information on the nature of this relationship of resilience on QoL. Our aim was to examine the relationship between resilience and quality of life in breast cancer patients.METHODS: QoL was measured in 218 consequent breast cancer patients, with EORTC - QLQ Core 30 questionnaire, and EORTC QLQ-BR23. The resilience was measured with Connor Davidson Resilience Scale.RESULTS: The global quality of life was positively correlated with the levels of resilience (R = 0.39 p < 0.001). All functional scales (physical, role, emotional, cognitive and social functioning was in a positive correlation with resilience. The symptoms severity (fatigue, nausea and vomitus, pain, dyspnea, insomnia, appetite loss, constipation, diarrhea, financial difficulties) was in negative correlation with resilience. Less resilient breast cancer patients reported worse body image and future perspective and suffered from more severe adverse effects of systemic therapy, and arm/breast symptoms. CONCLUSION: Our findings show that psychological resilience affects different aspects of health-related quality of life. More resilient patients have significantly better quality of life in almost all aspects of QoL.


2015 ◽  
Vol 3 (4) ◽  
pp. 661-665 ◽  
Author(s):  
Gordana Ristevska-Dimitrоvska ◽  
Petar Stefanovski ◽  
Snezhana Smichkoska ◽  
Marija Raleva ◽  
Beti Dejanova

OBJECTIVE: A significant number of breast cancer patients, during their life with the diagnosis, experience emotional distress in the form of depression and anxiety. Psychological resilience is the ability of a person to protect his/her mental health when faced with adverse circumstances such as the cancer diagnosis. This study aims to assess the resilience in breast cancer patients and to explore whether depression affects the resilience.MATERIAL AND METHODS: Two hundred eighteen (218) women, treated for early breast cancer responded to Connor - Davidson Resilience Scale and Hospital Depression and Anxiety Scale, in order to assess the level of psychological resilience and the level of depression.RESULTS: There is a significant negative correlation between depression and resilience in our sample (r = - 0.562, p < 0.001). Individuals with higher levels of depression have lower levels of psychological resilience. There is no statistically significant correlation between the ages of the participants; time passed since diagnosis, cancer stage and resilience levels.CONCLUSION: This study shows that patients who are less depressed have higher levels of resilience and that psychological resilience may independently contribute to lower levels of depression among breast cancer patients. The level of psychological resilience may be a protective factor for depression and psychological distress.


2018 ◽  
Vol 22 (3) ◽  
pp. 172-177 ◽  
Author(s):  
Evangelos C. Fradelos ◽  
Dimitra Latsou ◽  
Dimitroula Mitsi ◽  
Konstantinos Tsaras ◽  
Dimitra Lekka ◽  
...  

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