scholarly journals Part I Indium-mediated THP ring formation and transformation of halo group into hydroxyl group Part II Palladium-catalyzed direct arylation of cyclic enamides with arylmetallic reagents

2011 ◽  
Author(s):  
Hai Zhou
Keyword(s):  
Ring Formation ◽  
Hydroxyl Group ◽  
Direct Arylation ◽  
Palladium Catalyzed ◽  
Group Part

scholarly journals Palladium-catalyzed direct arylation and cyclization of o-iodobiaryls to a library of tetraphenylenes

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Chendan Zhu ◽  
Yue Zhao ◽  
Di Wang ◽  
Wei-Yin Sun ◽  
Zhuangzhi Shi
Keyword(s):  
Direct Arylation ◽  
Palladium Catalyzed

ChemInform Abstract: Palladium-Catalyzed Direct Arylation of Thiophenes Bearing SO2R Substituents.

ChemInform ◽  
2011 ◽  
Vol 42 (49) ◽  
pp. no-no
Author(s):  
Charles Beromeo Bheeter ◽  
Jitendra K. Bera ◽  
Henri Doucet
Keyword(s):  
Direct Arylation ◽  
Palladium Catalyzed

ChemInform Abstract: Formyl Substituent at C-4 of Pyrazoles: A Temporary Protecting Group for Regioselective Palladium-Catalyzed Direct Arylation at C-5.

ChemInform ◽  
2015 ◽  
Vol 46 (4) ◽  
pp. no-no
Author(s):  
Imen Smari ◽  
Chiraz Youssef ◽  
Kedong Yuan ◽  
Anissa Beladhria ◽  
Hamed Ben Ammar ◽  
...  
Keyword(s):  
Protecting Group ◽  
Direct Arylation ◽  
Palladium Catalyzed

ChemInform Abstract: Palladium-Catalyzed Direct Arylation Reactions

ChemInform ◽  
2010 ◽  
Vol 41 (9) ◽  
Author(s):  
Masahiro Miura ◽  
Tetsuya Satoh
Keyword(s):  
Direct Arylation ◽  
Palladium Catalyzed

Mechanistic Study on Gold(I)-Catalyzed Unsaturated Spiroketalization Reaction

2022 ◽  
Vol 19 ◽  
Author(s):  
Kamlesh Sharma
Keyword(s):  
Activation Barrier ◽  
Ring Formation ◽  
Hydroxyl Group ◽  
Mechanistic Study ◽  
Protecting Group ◽  
Wide Range ◽  
Oxocarbenium Ion ◽  
Metal Catalyzed ◽  
Insight Into ◽  
Mechanism Of The Reaction

Abstract: The mechanism of metal-catalyzed spiroketalization of propargyl acetonide is explored by employing DFT with the B3LYP/6-31+G(d) method. Acetonide is used as a regioselective regulator in the formation of monounsaturated spiroketal. The energies of transition states, intermediates, reactants and products are calculated to provide new insight into the mechanism of the reaction. The energetic features, validation of the observed trends in regioselectivity are conferred in terms of electronic indices via FMO analysis. The presence of acetonide facilitates a stepwise spiroketalization as it masks the competing nucleophile, and thus hydroxyl group present, exclusively acts as a nucleophile. The vinyl gold intermediate 3 is formed from 2 via activation barrier TS1. This is the first ring formation, which is 6-exo-dig cyclization. The intermediate 3 is converted into allenyl ether 4, which isomerizes to the intermediate oxocarbenium ion 5 via activation barrier TS2. The intermediate 5 cyclizes to 6 via TS3. This is the second ring formation. The intermediate 6 on protodeauration turns into 6,6-monounsaturated spiroketal 7. It is concluded that acetonide as a protecting group serves the purpose, and thus a wide range of spiroketals can be prepared, regioselectivity.

ChemInform Abstract: Direct Arylation of Thiophenes via Palladium-Catalyzed C—H Functionalization at Low Catalyst Loadings.

ChemInform ◽  
2008 ◽  
Vol 39 (14) ◽  
Author(s):  
Ahmed Battace ◽  
Mhamed Lemhadri ◽  
Touriya Zair ◽  
Henri Doucet ◽  
Maurice Santelli
Keyword(s):  
Direct Arylation ◽  
Palladium Catalyzed

scholarly journals Palladium-Catalyzed C12-Selective Direct Arylation of [1,2-c]Quinazolin-6(5H)-ones

Synthesis ◽  
2019 ◽  
Vol 51 (17) ◽  
pp. 3287-3294
Author(s):  
Antonio Arcadi ◽  
Sandro Cacchi ◽  
Giancarlo Fabrizi ◽  
Andrea Fochetti ◽  
Francesca Ghirga ◽  
...  
Keyword(s):  
Aryl Halides ◽  
Direct Arylation ◽  
Palladium Catalyzed ◽  
Straightforward Approach

A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2-c]quinazolin-6(5H)-ones through the palladium-catalyzed direct arylation of N-benzyl and NH-free [1,2-c]quinazolin-6(5H)-ones with aryl halides is described.

Sign in / Sign up

Export Citation Format

Share Document