scholarly journals Progesterone receptor ligand binding domain : from conformational dynamics to drug discovery

2019 ◽  
Author(s):  
Liangzhen Zheng
Keyword(s):  
Drug Discovery ◽  
Progesterone Receptor ◽  
Ligand Binding ◽  
Conformational Dynamics ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand

scholarly journals X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11β-Substituted Steroids

2012 ◽  
Vol 287 (24) ◽  
pp. 20333-20343 ◽  
Author(s):  
Scott J. Lusher ◽  
Hans C. A. Raaijmakers ◽  
Diep Vu-Pham ◽  
Bert Kazemier ◽  
Rolien Bosch ◽  
...  
Keyword(s):  
Progesterone Receptor ◽  
Ligand Binding ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand ◽  
X Ray

Simulations of the Estrogen Receptor Ligand-Binding Domain:  Affinity of Natural Ligands and Xenoestrogens

2000 ◽  
Vol 43 (24) ◽  
pp. 4594-4605 ◽  
Author(s):  
B. Chris Oostenbrink ◽  
Jed W. Pitera ◽  
Marola M. H. van Lipzig ◽  
John H. N. Meerman ◽  
Wilfred F. van Gunsteren
Keyword(s):  
Estrogen Receptor ◽  
Ligand Binding ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand ◽  
Natural Ligands ◽  
Estrogen Receptor Ligand
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