scholarly journals Green approach to Chemo-Selective N-Boc Protection of Amines using Catalytic amount of Lithium Hydroxide Monohydrate under Solvent Free Condition

2020 ◽  
pp. 06-12
Author(s):  
Sandip P. Gondake ◽  
Santosh R. Kshirsagar ◽  
Ashok S. Pise ◽  
Valmik S. Kapase ◽  
Sagar I. Shinde
Keyword(s):  
Reaction Times ◽  
Catalytic Amount ◽  
Lithium Hydroxide ◽  
Solvent Free ◽  
Side Reactions ◽  
Free Condition ◽  
Green Protocol ◽  
Solvent Free Condition ◽  
Lithium Hydroxide Monohydrate ◽  
Hydroxide Monohydrate

<p>The protecting group plays important role in synthesis of multifunctional targets. A simple rapid efficient and green method for chemo-selective N-Boc protection of amines using Lithium hydroxide as a green catalyst. In the present work amine protection in presence of ditert-butyl carbonate under solvent free condition is carried out. An efficient green protocol for chemoselctive N-Boc protection of aryl, aliphatic, aromatic, acyclic and hetero cyclic amines (1 m mol %)( 10, 20, 30) were carried out with ditert-butyl carbonate (Boc)2 O using Lithium hydroxide monohydrate (10 mol %) at room temperature under solvent free condition to give white solid monitored on TLC. No side reactions are observed .The present protocol were simple, rapid, efficient, shorter reaction times, high yielding, highly selective, economical and eco-friendly</p>

scholarly journals One-Pot Synthesis of Benzoxanthenes in Solvent Free Condition using Chloroaluminate Ionic Liquids as Catalyst

2009 ◽  
Vol 5 (1) ◽  
pp. 575-580
Author(s):  
Sugat Kirti ◽  
Dhanraj T. Masram
Keyword(s):  
Ionic Liquid ◽  
Reaction Times ◽  
Catalytic Amount ◽  
Solvent Free ◽  
Imidazolium Chloride ◽  
One Pot ◽  
Free Condition ◽  
Solvent Free Condition ◽  
Solvent Free Conditions ◽  
One Pot Condensation

A mild and efficient method has been developed for the preparation of 14-aryl-14H dibenzo[a,j]xanthenes from one-pot condensation of aldehydes with β-naphthol using catalytic amount of Chloroaluminate ionic liquid (imidazolium chloride·3AlCl3 or pyridiniumchloride·3AlCl3) under thermal solvent-free conditions. Excellent yields, short reaction times, easy workup and reusability of the catalyst as well as solvent free conditions are advantages of this procedure.

Traceless synthetic approach towards oxaza-dicyclopenta[a,h]naphthalenes under solvent-free condition: a basic alumina-supported green protocol

2013 ◽  
Vol 54 (24) ◽  
pp. 3046-3050 ◽  
Author(s):  
Rupankar Paira ◽  
Shyamal Mondal ◽  
Arpan Chowdhury ◽  
Maitreyee Banerjee ◽  
Arindam Maity ◽  
...  
Keyword(s):  
Solvent Free ◽  
Synthetic Approach ◽  
Free Condition ◽  
Green Protocol ◽  
Basic Alumina ◽  
Solvent Free Condition

scholarly journals A Facile One-Pot Solvent-Free Synthesis of 1,2-Dihydro-1-arylnaphtho[1,2-e][1,3]oxazine-3-ones Catalyzed by Wet Cyanuric Chloride

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Firouzeh Nemati ◽  
Azam Beyzai
Keyword(s):  
Organic Solvent ◽  
Simple Procedure ◽  
Reaction Times ◽  
Solvent Free ◽  
Cyanuric Chloride ◽  
One Pot ◽  
Free Condition ◽  
Solvent Free Condition ◽  
High Yields ◽  
Solvent Free Synthesis

A novel one-pot synthesis of 1,2-dihydro-1-arylnaphtho[1,2-e][1,3]oxazine-3-ones by condensation of a variety of aldehydes withβ-naphthol and urea or thiourea in the presence of wet cyanuric chloride under solvent-free condition has been described. High yields, simple procedure, easy workup, short reaction times, and avoiding the use of organic solvent are the advantages of this green methodology.

ChemInform Abstract: Traceless Synthetic Approach Towards Oxaza-dicyclopenta[a,h]naphthalenes under Solvent-Free Condition: A Basic Alumina Supported Green Protocol.

ChemInform ◽  
2013 ◽  
Vol 44 (39) ◽  
pp. no-no
Author(s):  
Rupankar Paira ◽  
Shyamal Mondal ◽  
Arpan Chowdhury ◽  
Maitreyee Banerjee ◽  
Arindam Maity ◽  
...  
Keyword(s):  
Solvent Free ◽  
Synthetic Approach ◽  
Free Condition ◽  
Green Protocol ◽  
Basic Alumina ◽  
Solvent Free Condition

scholarly journals Chitosan-silica Sulfate Nano Hybrid: An Efficient Biopolymer Based-heterogeneous Nano Catalyst for Solvent-free Synthesis of 3,4-Dihydropyrimidine-2(1H)-one/thiones

2021 ◽  
Vol 68 (2) ◽  
pp. 374-386
Author(s):  
Somayeh Behrouz ◽  
Masoome Nazar Abi ◽  
Mohammad Amin Piltan
Keyword(s):  
Biginelli Reaction ◽  
Reaction Times ◽  
Significant Loss ◽  
Solvent Free ◽  
Methyl Acetoacetate ◽  
Free Condition ◽  
Efficient Approach ◽  
Solvent Free Condition ◽  
Nano Catalyst ◽  
Solvent Free Synthesis

A green and highly efficient approach for the synthesis of 3,4-dihydropyrimidine-2(1H)-one/thione derivatives is described. In this approach, the three-component Biginelli reaction between (thio)urea, methyl acetoacetate and aldehydes under solvent-free condition in the presence of chitosan-silica sulfate nano hybrid (CSSNH) as a green and heterogeneous nano catalyst affords the corresponding products in good to excellent yields and in short reaction times. CSSNH is a cheap, eco-friendly, and non-toxic nano catalyst that could be easily prepared, handled, and reused for many reaction runs without significant loss of its activity.

scholarly journals 1-Methyl-3-(2-(sulfooxy)ethyl)-1H-imidazol-3-ium Chloride as a New and Green Ionic Liquid Catalyst for One-Pot Synthesis of Dihydropyrimidinones under Solvent-Free Condition

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Sami Sajjadifar ◽  
Eshagh Rezaee Nezhad ◽  
Ghasem Darvishi
Keyword(s):  
Ionic Liquid ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Simple Method ◽  
Free Condition ◽  
Multicomponent Condensation ◽  
Acidic Ionic Liquid ◽  
Solvent Free Condition ◽  
High Yields

An efficient and simple method for the preparation of 1-methyl-3-(2-(sulfooxy)ethyl)-1H-imidazol-3-ium chloride{(MSEI)Cl}as an acidic ionic liquid is described. One-pot multicomponent condensation of 1,3-dicarbonyl compounds, urea/thiourea and aldehydes at 80∘C affords the corresponding compounds in high yields and in short reaction times by using (MSEI)Cl.

Phase‐controlled synthesis of zeolites from sodium aluminosilicate under OSDA/solvent‐free condition

2021 ◽  
Author(s):  
Yoshitaka Mizuno ◽  
Koji Miyake ◽  
Shunsuke Tanaka ◽  
Norikazu Nishiyama ◽  
Choji Fukuhara ◽  
...  
Keyword(s):  
Solvent Free ◽  
Controlled Synthesis ◽  
Free Condition ◽  
Sodium Aluminosilicate ◽  
Solvent Free Condition

Sunlight‐Assisted Photocatalytic Sustainable Synthesis of 1,4‐Disubstituted 1,2,3‐Triazoles and Benzimidazoles Using TiO 2 −Cu 2 (OH)PO 4 Under Solvent‐Free Condition

2021 ◽  
Vol 6 (6) ◽  
pp. 1210-1215
Author(s):  
Tayyala Kiranmye ◽  
Murugan Vadivelu ◽  
Deviga Magadevan ◽  
Sugirdha Sampath ◽  
Kannabiran Parthasarathy ◽  
...  
Keyword(s):  
Solvent Free ◽  
Free Condition ◽  
Solvent Free Condition
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