scholarly journals Use of procalcitonin and C-reactive protein as predictors and diagnostic tool of acute appendicitis

2020 ◽  
Vol 3 (2) ◽  
pp. 163-170
Author(s):  
Kafiah Rahed ◽  
Tariq Midhat ◽  
Noor Raheef

The aim of the study was to evaluate the role of PCT and CRP in patients with acute appendicitis. The study was conducted in Kirkuk city for the period from January, 2018 to April, 2018 on 50 patients with acute appendicitis with age group 15-54 years. Based on the clinical signs of patients, diagnostic tests and sonar rays, the number of patients with acute appendicitis was assigned to the present study. The study also included 40 healthy persons as control group . The study included the collection of 3 ml of venous blood for identification and measurement of PCT by using ELISA technique and CRP test by using Commercial manual kits. The study also included taking of full information from cases like living situation, age . The study indicated that the maximum mean of PCT was observed in patients with acute appendicitis as compared with healthy persons (17.31±0.51 versus 6.22±0.34ng/ml) with highly significant difference between the two groups. The maximum rate of CRP +ve was observed in patients with acute appendicitis as compared with healthy persons (84% versus 10% ng/ml) with highly significant difference between the two groups. The study found that means of WBCs count and neutrophils count were significantly higher in patients with acute appendicitis as compared with healthy persons. The study showed that there was positive correlation of PCT and CRP with each of WBCs and neutrophil counts and a strong positive correlation of PCT with CRP in patients with acute appendicitis. The highest rate of patients with acute appendicitis (40%) was in the age group 15-24 years followed by the age group 25-34 years while the lowest rate was in the age group 45-54 years. It was concluded that PCT and CRP considered as in important non-invasive diagnostic tool of acute bacterial appendicitis

2020 ◽  
Author(s):  
Tianshu Gu ◽  
Lan Yao ◽  
Tong Sun ◽  
Sara W. Day ◽  
Scott C. Howard ◽  
...  

Abstract In view of the fact that the 2019-nCoV has spread to most countries in the world, it is necessary to make scientific and well-founded predictions of the current pandemic situation caused by the virus worldwide, which are conducive to public, social and government responses that mitigate and appropriately address the pandemic. We collected data from provinces with more than 200 cases in China and from eight other countries. Our analyses showed that the disease duration has no correlation with the number of patients, with r = 0.184. The number of deaths was not correlated to the disease duration, with r = 0.242. However, a positive correlation between the days of disease duration and infection rate, with a r = 0.626. Furthermore, there is a strong positive correlation between the disease duration and total death rate, with a r = 0.707. Using death rate of first 25 days, we obtained a positive relationship with a r value of 0.597. Based on the data from first 25 days, the minimum and maximum days of COVID-19 pandemic duration of eight countries was estimated between days of 37 and 114 days.


2018 ◽  
Vol 7 (2) ◽  
pp. 39-43
Author(s):  
Ashok Koirala ◽  
Dipendra Thakur ◽  
Sunit Agrawal ◽  
Bhuwan Lal Chaudhary ◽  
Sagar Poudel

 Background: Acute appendicitis is very common surgical cause of acute abdomen and needs surgical removal either by laparoscopic or open appendicectomy. The aim of this study is to compare frequency of surgical site infection (SSI) in patients undergoing laparoscopic and open appendicectomy. Materials and Methods: The study was prospective study conducted in NMCTH, Biratnagar. Total 200 patients with diagnosis of acute appendicitis admitted through the emergency department of our hospital were included in the study. The patients were randomly allocated in two groups: Laparoscopic appendicectomy group (LA) and Open appendicectomy group (OA). Both groups underwent successful emergency appendicectomy. Wound infections in terms of surgical site infection (SSI) if present were recorded. All age groups and both sexes were included.  Results: Two hundred patients underwent appendicectomy, one hundred Laparoscopic appendicectomy (LA) and another hundred open appendicectomy (OA). The mean age of patients with acute appendicitis was 30.63±16.14 years with minimum of 6 years and maximum of 77 years. The highest number of patients were in age group of 10 to 20 years (29.5%). In LA group SSI noted in 3 patients (3%) whereas in OA group it was found in 12 patients (12%). Conclusion: Laparoscopic appendicectomy is better and offers great advantages in terms of SSI as compared to Open appendicectomy.  


2019 ◽  
Vol 92 (1096) ◽  
pp. 20180793 ◽  
Author(s):  
Ali B Alhailiy ◽  
Ernest U Ekpo ◽  
Peter L Kench ◽  
Elaine A Ryan ◽  
Patrick C Brennan ◽  
...  

Objective: This study aimed to examine the associated factors for dose variation and influence cardiac CT angiography (CCTA) dose benchmarks in current CT imaging centres. Methods: A questionnaire was distributed to CT centres across Australia and Saudi Arabia. All participating centres collected data for adults who underwent a CCTA procedure. The questionnaire gathered information about the examination protocol, scanning parameters, patient parameters, and volume CT dose index (CTDI vol) and dose–length product (DLP). A stepwise regression analysis was performed to assess the contribution of tube voltage (kV), padding time technique, cross-sectional area (CSA) of chest and weight to DLP. Results: A total of 17 CT centres provided data for 423 CCTA examinations. The median CTDIvol, DLP and effective dose were 18 mGy, 256 mGy.cm and 5.2 mSv respectively. There was a statistically significant difference in DLP between retrospective and prospective ECG-gating modes (p = 0.001). Median DLP from CCTA using padding technique was 61% higher than CCTA without padding (p = 0.001). The stepwise regression showed that kV was the most significant predictor of DLP followed by padding technique then CSA while patient weight did not statistically significantly predict DLP. Correlation analysis showed a strong positive correlation between weight and CSA (r = 0.78), and there was a moderate positive correlation between weight and DLP (r = 0.42), as well as CSA and DLP (r = 0.48). Conclusion: Findings show radiation dose variations for CCTA. The associated factors for dose variation found in this study are scanning mode, kV, padding time technique and CSA of the chest. This results support the need to include CSA measurements in future dose survey and for setting DRLs. Advances in knowledge: The study provides baseline information that helps to understand the associated factors for dose variations and high doses within and between centres performing CCTA.


2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Gözde Derviş Hakim ◽  
Şafak Kızıltaş ◽  
Hilmi Çiftçi ◽  
Şafak Göktaş ◽  
İlyas Tuncer

Background and Aims. We aimed to investigate the prevalence of Giardiasis in patients with dyspepsia and patients with diabetes mellitus. Methods. 400 patients and 100 healthy persons were included in this clinical prospective study. The number of patients in each group was equal, 200 dyspeptic and 200 diabetic, respectively. The antigen of G. lntestinalis was determined in the stool specimens by ELISA method. Results. The frequency of Giardiasis was 7% in dyspeptic and 15% in diabetic patients. There was no positive results in any of the healthy persons. There was a significant difference in prevalence rate of Giardiasis between patients with dyspepsia and diabetes mellitus (P<0.05). Conclusions. These results revealed that the prevalence of Giardiasis in dyspepsia and with diabetes mellitus was high in our country. This is the first study investigating the prevalence of Giardiasis in diabetic patients. To investigate Giardiasis in diabetic patients, who have dyspepsia or not, may be a good approach for public health.


2015 ◽  
Vol 2 (2) ◽  
Author(s):  
Lakshmi Arun ◽  
Dr. Ravikumar M B ◽  
Arushi J Makhija ◽  
Shonali Christine Barreto ◽  
Vidhya Vishwanathan

This study examines Self-concept in relationship with Family environment among adolescents. The study involved a total of 137 adolescents in the age group from 17-19 years, Adolescents’s Self Concept Scale – CSCS and CYDS Family Environment Scale was used to measure self-concept and family environment among adolescents. Then the data was scored and statistically analyses by using t-test and correlation. The result of the study revealed that there is no significant difference between male and female adolescents in their self-concept, and also there is no significant difference between male and female in their family environment. There is a highly significant positive correlation between self concept and family environment among adolescents.


Author(s):  
Anthony Chibuike Onyebueke ◽  
Ancilla Kate Umeobieri ◽  
Kindness Chidi Irikannu

Aim: To determine the level, sources of awareness, ownership and utilization of Insecticide Treated Nets (ITNs) by pregnant women, according to age, parity, trimester, occupation and hospital attended. Study Design: The study was a cross sectional survey of 577 randomly selected pregnant women who were attending antenatal clinic in different hospitals in Awka Metropolis, Anambra State, Nigeria. Duration of Study: The study was conducted in February 2016. Materials and Methods: A semi-structured questionnaire was used to obtain information from the study participants. Results: Of a total of 577 respondents, 566(98.1%) had previous knowledge of ITNs while only 11(1.9%) had no prior knowledge. Also, 218(38.5%) had heard about ITNs from Radio, 184(32.5%) from Television, while 374(66.1%) from Antenatal clinics. A total of 217(46.2%) obtained at least one net at antenatal clinic, 39(8.3%) purchased at least one of the ITNs owned, 49(10.4%) received the net at their Local Government Headquarters while 263(66.9%) received at least one by free distribution at other locations. Respondents from government owned Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOUTH) had the highest ownership rate of 92.7%, while least 65.0% was observed at the privately owned Divine Hospital and Maternity. The ownership of ITNs was dependent on the hospital as there was a significant difference (X2=56.374, df=2, p < .05). Age group 25–34 years had the highest ownership rate of 87.1% while the least 72.8% was in age group 15–24 years. Women in age group 35–44 years had the highest utilization rate of 52.3% while least usage rate was in age group 15-24 years and there was a significant difference (X2=7.042, df=2, p < .05). Conclusion: Public health educators, Doctors and Antenatal heads need to do more in sensitization on the importance of utilization of ITNs during pregnancy for protection against malaria vectors.


2021 ◽  
Vol 8 ◽  
Author(s):  
Rreze M. Gecaj ◽  
Flutura C. Ajazi ◽  
Hysen Bytyqi ◽  
Blerta Mehmedi ◽  
Hazir Çadraku ◽  
...  

This study was aimed for the evaluation of somatic cell count (SCC), physicochemical, and microbiological parameters during the end of lactation in the raw milk of Alpine and native Red goat breed. In the experiment, 102 milk samples from Alpine and native Red goats were included. Two different groups within the same breed were analyzed: a group consisting of animals in their first lactation and the second group consisting of animals from the fifth lactation. The milk samples were individually and daily collected during late lactation for three consecutive weeks, and milk fat, protein, lactose, SCC, and total bacteria with enterobacteria were assessed. Fresh milk of goats from late lactation period had a number of somatic cells (SC) within the expected value with log10 of 5.8–6.18 cells/ml for the compared groups. In both breeds, the total mesophilic bacteria were fewer in numbers, however, in the native Red goat, a larger population of such bacteria was enumerated. The number of coliforms and enterobacteria was below 100 cfu/ml. In the current study, we were able to show a significant difference among the studied breeds depending on lactation and season for fat (p = 0.002), but not for lactose and protein content. A positive correlation for total protein (TP), lactose, and fat as well as for lactose and SCC was found in the native Red goat breed. In the Alpine goat breed, a strong positive correlation (0.821**) was found for lactose and enterobacteria count (EC). In conclusion, these findings evaluate different goat milk parameters during late lactation period and provide an indirect measure to monitor goat mammary gland health for both breeds.


Author(s):  
Shailesh B. Patil ◽  
Milind B. Patil

Background: It is certain from clinical experience of many that one or more hemorrhages in early pregnancy can still end up in good fetal outcome. So, our study deals with comparison of cytohormonal study in pregnancy and threatened abortion. The study was conducted with the aim of utilizing colpocytogram as a tool in assessing and treating cases of threatened abortion and comparing them with normal pregnant women.Methods: Patients attending antenatal care unit on outdoor basis and labelled as normal pregnancy cases were considered as control group. The patients of threatened abortion were studied when they were admitted in Gynecology department for indoor treatment. Patients were studied taking into consideration their age, parity, number of abortions, complaints (P/V bleeding, pain in abdomen), gestational age, per abdomen and per vaginal findings and also USG findings and vaginal smear pattern.Results: Maximum number of patients was present in the age group of 21-25 years in both the groups. While only 13.33% had normal smear pattern in threatened abortion group. 86.67% patients in threatened abortion group showed abnormal smear pattern. There is statistically significant difference was found (p<0.05). There is statistically significant was found (P<0.01) and indicates good effects of the drug on the vaginal epithelium.Conclusions: The cytohormonal study acts as a simple, reliable, good, noninvasive method for evaluation of hormonal pattern in normal pregnancy and threatened abortion. 


2014 ◽  
Vol 2 (11_suppl3) ◽  
pp. 2325967114S0017
Author(s):  
Zeynep Hazar ◽  
Naime Ulug ◽  
Inci Yuksel

Objectives: Little is known about the relationship between core stability and shoulder dysfunction in shoulder impingement syndrome. The purpose of this study was to analyze the difference between healthy volunteers and patients with shoulder dysfunction in regard to core stability measures. Secondary purpose was to explore the relationship between measures of core stability and measures of shoulder dysfunction. Methods: 15 patients with shoulder impingement syndrome (mean age: 32.2±4.2 years) and 15 healthy volunteers (mean age: 33.8±6.2 years) participated in this study. Sorenson test, front plank and side bridge exercise was performed to assess anterior, lateral and posterior core endurance, respectively. Simple shoulder test (SSS) and seated medicine ball throw test was used to evaluate the functions of the shoulder joints. Mann-Whitney U test was used for comparison of variables between groups. Analyses of relationships between variables were examined with Spearman correlation test. Results: There was a statistically significant difference between patients with shoulder impingement syndrome and healthy controls in core stability and function (p<0.05). A strong positive correlation was found between shoulder functional test (SSS) and lateral bridge test (r= .874, p < .05). Additionally, a modest positive correlation was found between the SSS and the Sorenson test at (r= .695, p < .05), and a weak positive correlation was found between the SSS and the front plank test at (r= .365, p < .05). Conclusion: Core stability and functional deficiency was found in patients with subacromial impingement syndrome. According to this study, greater shoulder dysfunction is correlated with greater stability deficiency. Therapists should consider incorporating core strengthening as an integral component of rehabilitation program in patients with shoulder dysfunction.


2017 ◽  
Vol 32 (1) ◽  
pp. 50-54
Author(s):  
Mohammed Abaye Deen Saleh ◽  
Pratyay Hasan ◽  
Khyrun Nahar ◽  
Abdul Wadud Chowdhury ◽  
Mohsin Ahmed ◽  
...  

Aortic sclerosis (ASc) is defined as thickening or calcification of the aortic valve without significant obstruction of blood flow. Aortic sclerosis is diagnosed when in echocardiography, thickening and calcification of one or more cusps of a tricuspid aortic valve is manifested, whereas in aortic stenosis, cusp separation is restricted and the velocity through the aortic valve is > 2.5 m/s. Its prevalence increases with age. Aortic valve stenosis is associated with systemic endothelial dysfunction, and it carries a 50% increase in risk of cardiac death or myocardial infarction. As aortic sclerosis has proved to be more and more relevant in recent days, it has been important to identify epidemiological data and demographic information of aortic sclerosis in Bangladeshi population. This study tried to determine age distribution of aortic sclerosis in Bangladehsi population. Median age of aortic sclerosis patients was 65 years (mean 67 ± 12 years), most of the patients (17.2%) were in 56-60 years of age group. The same statement holds correct for females, where highest number of patients (7.7% of total patients) were in the same age group. For the males, the highest number of patients (11% of total patients) were in 61-65 years of age group. The minimum age was 45 years for both males and females. Although the minimum age is same for both sex, females are affected a bit earlier than males, and statistically significant difference was found between mean ages of two sexes. Most of the aortic sclerotic patients are below the usually used age cut off of 65 years. There is significant difference between mean age of presentation of aortic sclerosis between males and females. Further study should be undertaken to understand these effects more clearly.Bangladesh Heart Journal 2017; 32(1) : 50-54


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