scholarly journals Some epidemiological data about Stomach Cancer in Kosovo.

2021 ◽  
Vol 5 (2) ◽  
pp. 864-868
Author(s):  
Imri Vishi ◽  
Agron Dogjani ◽  
Arben Gjata ◽  
Kastriot Haxhirexha ◽  
Hysni Bendo
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Stomach Cancer ◽  
Epigastric Pain ◽  
Epidemiological Data ◽  
Tumor Stage ◽  
The Body ◽  
Medical Centers ◽  
Clinical Center ◽  
Loss Of Appetite

Despite the continuing decline in incidence, stomach cancer remains one of the most common and deadly neoplasms in the world [1]. According to the literature, stomach cancer is the third leading cause of cancer deaths worldwide, ranking third after lung cancer and colorectal in global cancer mortality. About 1 in 12 neoplasm deaths can be attributed to stomach cancer, which has 5 times the highest incidence among all cancers, and over one million new cases of stomach cancer are diagnosed each year worldwide.[2] Our objectives were: Evidence and detailed statistical description of demographic, diagnostic, clinical, pathological data of stomach cancer patients are included in this study were hospitalized in two clinical surgery medical centers in the period from January 2009 to January 2019, in University Clinical Center in Prishtina-Department of Surgery, Regional Hospital in Ferizaj-Department of Surgery. Material and methods; The study included 115 patients who met the criteria, and the Study variables were obtained from clinical record data that include: Gender (Male, Female); Age; Clinic of the disease: (indigestion Weakness, Weight loss, anorexia, Melena, Abdominal pain, Epigastric pain, Vomiting…); Tumor stage, histopathologic and lesion type... Conclusion; Stomach cancer affects both sexes with a preference of men with a ratio of 1.4: 1 (M; F). The most affected age group is 51-70 years which includes about 61.3% of patients. Depending on the localization of gastric cancer, the most affected part of our study was the body of the stomach (46%), the antral part 38%, the cardia part with 15.7%. Typical symptoms in our patients included; Indigestion 46 (40%); Loss of appetite 41 (35.6%); Abdominal pain 70(60.8%); Nausea/ vomiting 35( 30.4%); Postprandial pain 39 (33.9%); Weight loss 56 (48.6%); Melena 19 (16.5%)...

Does Cholecystectomy Prior to the Diagnosis of Pancreatic Cancer Affect Outcome?

2008 ◽  
Vol 74 (7) ◽  
pp. 602-606 ◽  
Author(s):  
Stephen H. Gray ◽  
Mary T. Hawn ◽  
Meredith L. Kilgore ◽  
Huifeng Yun ◽  
John D. Christein
Keyword(s):  
Pancreatic Cancer ◽  
Weight Loss ◽  
Abdominal Pain ◽  
Early Diagnosis ◽  
Cancer Diagnosis ◽  
Curative Resection ◽  
Tumor Stage ◽  
Seer Database ◽  
Patient Demographics ◽  
Medicare Data

Early diagnosis and curative resection are significant predictors of survival in patients with pancreatic cancer. We hypothesize that cholecystectomy within 12 months of pancreatic cancer affects 1-year survival. The Surveillance Epidemiology and End Result (SEER) database linked to Medicare data was used to identify patients diagnosed with pancreatic cancer who underwent cholecystectomy 1 to 12 months prior to cancer diagnosis. The SEER database identified 32,569 patients from 1995 to 2002; 415 (1.3%) underwent cholecystectomy prior to cancer diagnosis. Patients who underwent cholecystectomy had a higher proportion of diabetes (40.2% vs 20.5%; P < 0.01), obesity (8.9% vs 3.1%; P < 0.01), jaundice (17.3% vs 0.7%; P < 0.01), cholelithiasis (70.4% vs 4.2%; P < 0.01), choledocholithiasis (0.7% vs 0.0%; P < 0.01), weight loss (17.3% vs 4.7%; P < 0.01), abdominal pain (79.5% vs 22.5%), steatorrhea (0.7% vs 0.0%; P < 0.01), and cholecystitis (32.3% vs 1.7%; P < 0.0001). After controlling for tumor stage, patient demographics, and symptoms, survival at 1 year was significantly lower in patients undergoing cholecystectomy (OR, 0.75; 95% CI, 0.58–0.97). Recent cholecystectomy is associated with decreased 1-year survival among patients with pancreatic cancer. For patients older than 65 years of age, further evaluation prior to cholecystectomy may be necessary to exclude pancreatic cancer, especially patients with jaundice, weight loss, and steatorrhea.

scholarly journals Agenesis of the dorsal pancreas presenting with diabetic ketoacidosis – a case report and literature review

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Tian Yang ◽  
Xudan Yang ◽  
Luping Wang ◽  
Jun Mo
Keyword(s):  
Abdominal Pain ◽  
Glucose Metabolism ◽  
Diabetic Ketoacidosis ◽  
Epigastric Pain ◽  
English Literature ◽  
Pancreatic Enzyme ◽  
The Body ◽  
Glucose Metabolism Disorders ◽  
Dorsal Pancreas ◽  
Metabolism Disorder

Abstract Background Agenesis of the dorsal pancreas (ADP) is clinically rare, and it is usually accompanied by abdominal pain. Various disorders of glucose metabolism associating with ADP have been reported, but there are only two studies reporting a correlation between ADP and DKA in English literature. Case presentation We present a case of a patient with ADP accompanied by abdominal pain and diabetic ketoacidosis as the initial clinical presentation. A 30-year-old man presented with a 3-month history of recurrent onset of persistent mild epigastric pain, which worsen when eating. Laboratory tests revealed metabolic acidosis, hyperglycemia, and ketonuria. Phase contrast CT and MRCP showed the absence of the body and tail of the pancreas, as well as the dorsal pancreatic duct. The C-peptide release test indicated β-cell dysfunction. A combination therapy of insulin, pancreatic enzyme supplements, and mosapride citrate were administrated and the pain gradually resolved. Conclusions As glucose metabolism disorders can vary across different individuals, we advise clinicians to consider the diagnosis of ADP for a patient who presents with a glucose metabolism disorder accompanied by abdominal pain, pancreatitis or steatorrhea.

scholarly journals A Rare Case of Cystic Schwannoma of the Portal Triad

2016 ◽  
Vol 28 (1) ◽  
pp. 33 ◽  
Author(s):  
Dimitrios Avgerinos ◽  
Meshach Heenatigala ◽  
Andrew Lo
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Back Pain ◽  
Rare Case ◽  
The Body ◽  
Portal Triad ◽  
Pancreatic Cystadenoma ◽  
Time Of Operation ◽  
Cystic Schwannoma ◽  
Vague Abdominal Pain

Schwannomas can occur anywhere throughout the body andhave often been mistaken for more-sinister lesions, especiallywhen found in relation to the pancreas. Clinical symptomsrange from none to vague abdominal pain, back pain,anorexia, weight loss, vomiting, jaundice, and episodes ofcholangitis and gastrointestinal bleeding. Preoperative diagnosisis difficult, and endoscopic ultrasound with fine-needleaspiration is often limited in specificity. Given the low statisticallikelihood of schwannomas, therapy is usually targeted at thepossibility of pancreatic cystadenoma/cystadenocarcinoma.Simple enucleation is usually the preferred treatment, anddiagnosis can be established at the time of operation by frozensection. Schwannomas can be malignant, but preoperativeimaging and pathology can help establish the benign natureof most specimens. Patients typically do well with resolution ofsymptoms. Here we present the case of a patient with abdominalpain and a peripancreatic mass observed with computedtomography, who was found to have a cystic schwannomaextending from the portal triad. The mass was removed andthe patient was discharged without complications.

scholarly journals A 17 year old girl with gradual swelling of lower abdomen

2018 ◽  
Vol 11 (2) ◽  
pp. 180
Author(s):  
Sayada Fatema Khatun ◽  
Sabera Khatun ◽  
A. K. M. Farhad Hossain ◽  
Khairun Nahar
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Precocious Puberty ◽  
Growth Retardation ◽  
Bowel Habit ◽  
Lower Abdomen ◽  
Secondary Sexual Characteristic ◽  
History Of ◽  
Loss Of Appetite ◽  
Sexual Characteristic

<p><span>This article has no abstract. The first 100 words appear below:</span></p><p>A 17 year old girl presented at the outpatient department with the history of gradual swelling of lower abdomen, early onset of menstruation (precocious puberty) at the age of 7 years followed by secondary amenorrhea for 10 years, growth retardation and breast atrophy. She also complained that her secondary sexual characteristic did not develop. She had no family history of growth retardation or precocious puberty. Her breast showed infantile growth. She had no history of fever, abdominal pain, alteration of bowel habit, weight loss, or loss of appetite. On examination, she was afebrile and vitally stable.</p>

Case 4.24

2014 ◽  
pp. 232-233
Author(s):  
Christine U. Lee ◽  
James F. Glockner
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Splenic Artery ◽  
Arterial Phase ◽  
Axial Diffusion ◽  
Pancreatic Tail ◽  
Weighted Image ◽  
Contrast Enhanced ◽  
Loss Of Appetite ◽  
Upper Abdominal

66-year-old woman with loss of appetite, weight loss, fatigue, and upper abdominal pain VR image from 3D contrast-enhanced MRA (Figure 4.24.1) shows marked irregularity of the distal splenic artery. Axial diffusion-weighted image (b=600 s/mm2) (Figure 4.24.2) reveals a hyperintense mass in the pancreatic tail. Axial arterial phase postgadolinium 3D SPGR images (...

An unusual presentation of epigastric pain due to thrombophlebitis of a recanalised umbilical vein – case report

2019 ◽  
Vol 98 (8) ◽  
pp. 326-327 ◽  
Keyword(s):  
Liver Cirrhosis ◽  
Abdominal Pain ◽  
Case Report ◽  
Portal Hypertension ◽  
Liver Disease ◽  
Epigastric Pain ◽  
Umbilical Vein ◽  
History Of ◽  
Clinically Significant ◽  
Inflammatory Changes

Introduction: The umbilical vein can become recanalised due to portal hypertension in patients with liver cirrhosis but the condition is rarely clinically significant. Although bleeding from this enlarged vein is a known complication, the finding of thrombophlebitis has not been previously described. Case report: We report the case of a 62-year-old male with a history of liver cirrhosis due to alcoholic liver disease presenting to hospital with epigastric pain. A CT scan of the patient’s abdomen revealed a thrombus with surrounding inflammatory changes in a recanalised umbilical vein. The patient was managed conservatively and was discharged home the following day. Conclusion: Thrombophlebitis of a recanalised umbilical vein is a rare cause of abdominal pain in patients with liver cirrhosis.

Assessment of indicators of nervous and emotional stress in medical center personnel depending on the characteristics of their professional activity

2020 ◽  
Vol 60 (10) ◽  
pp. 650-657
Author(s):  
Irina V. Fedotova ◽  
Tatyana N. Vasilyeva ◽  
Tatyana V. Blinova ◽  
Irina A. Umnyagina ◽  
Yuliya V. Lyapina ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Emotional Stress ◽  
Functional State ◽  
Working Conditions ◽  
Medical Staff ◽  
Medical Center ◽  
The Body ◽  
Office Workers ◽  
Glutathione System ◽  
Medical Centers

Introduction. Digital technologies are actively used in the work of specialists of medical centers of various profiles, which causes the impact on employees of a number of professional factors that determine the characteristics of their work. The aim of the study is to evaluate the influence of professional factors on the functional state of the employees' body and the glutathione system as an objective indicator of stress based on the analysis of the subjective perception of the medical center employees of the specifics of working with personal computers and psychophysiological testing. Materials and methods. The study involved 109 specialists of medical centers (25 ophthalmologists, 31 representatives of the secondary medical staff - nurses and paramedics, 53 office employees). The anonymous survey concerned the assessment of working conditions and their impact on the functional state of the body of the respondents. Performance and stress tolerance indicators were evaluated using three standard questionnaires. The study of 66 subjects' levels of glutathione in the blood: total, reduced, oxidized and the ratio of reduced and oxidized - was used to analyze the relationship of the neuro-emotional nature of labor with the reaction of oxidative stress. Statistical processing of the obtained data was carried out using traditional methods of variation statistics and calculating the value of the odds ratio (OR) with a 95% confidence interval (CI). Results. The survey revealed a significant proportion of people in all groups of respondents who constantly use computer technology in their work. Describing the quality of the processed information, doctors more than representatives of other groups note its complexity, importance, negative emotional color, a high degree of responsibility and tension. Doctors more often than average medical staff and office workers associate the manifestation of fatigue with an uncomfortable state of the visual organ, nervous system, and musculoskeletal system. The subjects showed reduced performance and stress tolerance with the most pronounced negative trends in the group of doctors. Changes in the glutathione system were detected, indicating the presence of oxidative stress in 40% of ophthalmologists and office workers, and in half of nurses. Conclusions. The work of specialists of medical centers of various profiles in accordance with their assessment is characterized by high nervous and emotional stress, due to the need to process a significant amount of complex and important professionally significant information. Subjectively noted by respondents the influence of working conditions on the functional state of the body is confirmed by indicators of the glutathione system, which can be used as indicators of nervous and emotional stress.

scholarly journals Clinical characteristics and quality of life among Sri Lankan patients with chronic pancreatitis

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097987
Author(s):  
Umesh Jayarajah ◽  
Thisaru Widyarathne ◽  
Metthananda Nawarathne ◽  
Sivananthan Raguvaran ◽  
Nishanthan Subramaniam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Chronic Pancreatitis ◽  
Clinical Characteristics ◽  
Considerable Proportion ◽  
Intractable Pain ◽  
Life Questionnaire ◽  
European Organization ◽  
Loss Of Appetite

Objective We aimed to describe the clinical characteristics of chronic pancreatitis (CP) and patient quality of life (QOL) in a resource-limited setting. Methods We performed a cross-sectional study including patients with clinical and radiological features of CP. We collected clinical data and assessed QOL using the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire. Results We included 103 patients (median age 44 years, 84 men). Median age at symptom onset was 36 (4–78) years. Around 70% of patients had diabetes mellitus and 62.1% had consumed alcohol; 36 (35%) were current smokers. The mean overall global QOL score was 68.7. Most patients (91.3%) sought treatment from multiple centers. Nineteen (18.5%) had pancreatic stone disease, 38 (36.9%) had persistent abdominal pain (median severity 7.8/10, 59 (57.3%) had steatorrhea, and 56 (54.4%) had jaundice. Poor QOL was significantly associated with weight loss, loss of appetite, and intractable pain. No correlation with age, sex, or alcohol consumption was noted. Conclusion A considerable proportion of patients with CP had troublesome symptoms. Intractable pain, loss of appetite, and weight loss were significantly associated with poor QOL. Further assessment is needed of patients’ psychosocial well-being and its association with QOL.

scholarly journals Diagnostic utility of alarm features in predicting malignancy in patients with dyspeptic symptoms

2021 ◽  
Author(s):  
Anurag Shetty ◽  
Girisha Balaraju ◽  
Shiran Shetty ◽  
Cannanore Ganesh Pai
Keyword(s):  
Weight Loss ◽  
Epigastric Pain ◽  
Characteristic Curve ◽  
Abdominal Mass ◽  
Screening Tools ◽  
Disease Epidemiology ◽  
Dyspeptic Symptoms ◽  
Malignant Lesions ◽  
Alarm Features ◽  
Gastric Malignancy

Abstract Background Clinical features are of modest benefit in determining the etiology of dyspepsia. Dyspeptic patients with alarm features are suspected to have malignancy; but the proportions of patients and true cutoff values of various quantitative parameters in predicting malignancy are explored to a lesser extent. Methods This is a prospective observational study of consecutive patients undergoing esophagogastroduodenoscopy (EGD) for dyspeptic symptoms. Patients’ alarm features and clinical details were recorded in a predesigned questionnaire. The diagnostic accuracy of alarm features in predicting malignancy was studied. Results Nine hundred patients, 678 (75.3%) males, with a mean (standard deviation [SD]) age of 44.6 (13.54) years were enrolled. Commonest indication for EGD was epigastric pain in 614 (68.2%) patients. Dyspepsia was functional in 311 (34.6%) patients. EGD revealed benign lesions in 340 (37.8%) and malignancy in 50 (5.5%) patients. Among the malignant lesions, gastric malignancy was present in 28 (56%) and esophageal malignancy in 20 (40%) patients. Alarm features were present in 206 (22.9%), out of which malignant lesions were seen in 46 (22.3%) patients. Altogether, the alarm features had a sensitivity of 92% and specificity of 81.2% for predicting malignancy. The sensitivity and specificity for weight loss were 76% and 90.8%, while that of abdominal mass were 10% and 99.9% respectively. Based on receiver operating characteristic curve, the optimal age for screening of malignancy was 46.5 years in this population. Conclusions Patients of age group 40 to 49 years with dyspeptic alarm symptoms (predominant weight loss) need prompt endoscopy to screen for malignancy. The alarm features are inexpensive screening tools, found to be useful in India, and should be utilized in countries with similar healthcare conditions and disease epidemiology.

scholarly journals Seronegative Arthritis as a Complication of Whipple’s Disease

2021 ◽  
Vol 14 ◽  
pp. 117954762110177
Author(s):  
Rebecca DeBoer ◽  
Sahani Jayatilaka ◽  
Anthony Donato
Keyword(s):  
Rheumatoid Arthritis ◽  
Weight Loss ◽  
Abdominal Pain ◽  
Gastrointestinal Symptoms ◽  
Whipple’S Disease ◽  
Seronegative Arthritis ◽  
Whipple's Disease ◽  
Caucasian Male

Whipple’s disease (WD) is an uncommon cause of seronegative arthritis. WD is known for its gastrointestinal symptoms of diarrhea, weight loss, and abdominal pain. However, arthritis may precede gastrointestinal symptoms by 6 to 7 years. We describe a case of an 85-year-old Caucasian male with multiple joint complaints, not responsive to traditional treatments for conditions such as rheumatoid arthritis and osteoarthritis. We suggest that WD be considered for seronegative arthritis especially affecting large joints.

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