scholarly journals Benign epithelial tumor of salivary glands

2020 ◽  
Author(s):  
Keyword(s):  
Salivary Glands ◽  
Epithelial Tumor ◽  
Benign Epithelial Tumor

scholarly journals Bilateral Inverted Papilloma of the Paranasal Sinus: Literature Review

2011 ◽  
Vol 4 (3) ◽  
pp. 141-144
Author(s):  
Juan Ramon Gras-Cabrerizo ◽  
Joan R Montserrat-Gili ◽  
Albert Pujol Olmo ◽  
Manuel de Juan ◽  
Humbert Massegur-Solench
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Unusual Case ◽  
Functional Endoscopic Sinus Surgery ◽  
Inverted Papilloma ◽  
Sinus Surgery ◽  
Rare Entity ◽  
Epithelial Tumor ◽  
Sinonasal Papilloma ◽  
Benign Epithelial Tumor

ABSTRACT Objective We describe an unusual case of bilateral nasal inverted papilloma. Case report Inverted papilloma is a benign epithelial tumor that frequently occurs unilaterally. We report a 65-year-old male patient with a bilateral inverted papilloma located in the ethmoid and maxillary sinus. Functional endoscopic sinus surgery was performed in order to completely remove both tumors. Conclusion We present a rare entity of bilateral independent sinonasal papilloma treated successfully with endoscopic sinus approach.

scholarly journals Aciniccell carcinoma of the salivary glands: clinical and histopathological study of 12 cases

2021 ◽  
Vol 31 (3) ◽  
pp. 12-23
Author(s):  
ME Samar ◽  
◽  
RE Avila ◽  
RV Ferraris ◽  
PE Garcia ◽  
...  
Keyword(s):  
Salivary Glands ◽  
Cell Types ◽  
Cell Labeling ◽  
World Health ◽  
Numerical Code ◽  
Glandular Cell ◽  
Histopathological Study ◽  
Low Grade ◽  
Epithelial Tumor ◽  
Glandular Cells

Objective:Acinic cell carcinoma (CCA) is the third malignant epithelial tumor of the salivary glands in adults; low-grade tumor of malignancy, composed of neoplastic cells with serous acinar differentiation. The objective of this work was to analyze 12 cases of CCA according to their location, clinical characteristics, histological and immunohistochemical pattern and cell types, following the latest classification of the World Health Organization. Methods: The study included 12 cases of CCA from the files of salivary tumor biopsies of our work team, corresponding to the period 1997-2020. A numerical code was used to identify the samples, preserving the identity of the patients. Histological sections of the paraffin-embedded biopsies were evaluated with H/E, PAS and Toluidine blue and immunostained with the monoclonal antibodies pancytokeratin AE1 / AE3, Ki67, MUC-1 and mammaglobin. Results: The most frequent histologic pattern was the solid type as a single pattern or integrated with other patterns of lesser development, with almost exclusive location in the parotid gland and more frequent in women. Cells like normal acinar serocytes predominated in the solid growth pattern. The most frequent cell type in the microcystic patternwas the nonspecific glandular cell together with a lower proportion of acinar and intercalated duct-like cells. The papillary-cystic pattern was lined by nonspecific glandular cells. No clear cells found. With Ki67 a low cell proliferation was demonstrated in all the cases studied. Cell labeling for MUC-1 was grade 1 positive (less than 10% immunoreactive cells) and negative for mammaglobin.Conclusions: Patient follow-up is a priority because CCA tends to recur and metastasize and its behavior can become aggressive. We must deepen the study of its proliferative capacity as a treatment and prognosis tool, especially with immunohistochemistry and standardized molecular biology methods.

scholarly journals Sustained Akt Activity Is Required to Maintain Cell Viability in Seborrheic Keratosis, a Benign Epithelial Tumor

2016 ◽  
Vol 136 (3) ◽  
pp. 696-705 ◽  
Author(s):  
Victor A. Neel ◽  
Kristina Todorova ◽  
Jun Wang ◽  
Eunjeong Kwon ◽  
Minjeong Kang ◽  
...  
Keyword(s):  
Cell Viability ◽  
Seborrheic Keratosis ◽  
Epithelial Tumor ◽  
Benign Epithelial Tumor

scholarly journals Successful Treatment of Adult-Onset Recurrent Respiratory Papillomatosis with CO2 Laser and Photodynamic Therapy

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Sheng Lu ◽  
Yang Liu ◽  
Runjie Shi ◽  
Pingyu Zhou
Keyword(s):  
Adverse Reaction ◽  
Photodynamic Therapy ◽  
Human Papillomavirus ◽  
Rapid Growth ◽  
Aminolevulinic Acid ◽  
Recurrent Respiratory Papillomatosis ◽  
Adult Onset ◽  
Epithelial Tumor ◽  
Benign Epithelial Tumor

Recurrent respiratory papillomatosis is a noninvasive benign epithelial tumor caused by human papillomavirus. Clinically, it featured rapid growth, multifocus, and frequent recurrence. Though a number of therapies have been investigated, the recurrence after treatment is always a challenge. In this report, we describe a 27-year-old male patient with recurrent respiratory papillomatosis who was treated with CO2 laser therapy followed by 5-aminolevulinic acid photodynamic therapy (ALA-PDT). There was no adverse reaction after treatment and no recurrence during the follow-up time.

scholarly journals Nonintestinal-Type Sinonasal Adenocarcinoma

2009 ◽  
Vol 24 (2) ◽  
pp. 41-42
Author(s):  
Jose M. Carnate
Keyword(s):  
Salivary Gland ◽  
Nasal Cavity ◽  
Salivary Glands ◽  
Intestinal Type ◽  
Low Grade ◽  
High Grade ◽  
Epithelial Tumor ◽  
Poorly Differentiated ◽  
Well Differentiated ◽  
Gland Type

Malignant glandular neoplasms of the sinonasal tract originate either from the respiratory epithelium or the underlying mucoserous glands. They present with a confusing array of morphologic features and this is reflected in the nomenclature of these tumors. These tumors are grouped into three main types: salivary gland-type, intestinal-type and non-intestinal type adenocarcinomas.1 Salivary gland-type adenocarcinomas of the nasal cavity histologically resemble their analogous lesions in the major and minor salivary glands. Adenoid cystic carcinoma is the most common although almost any of those described in the salivary glands can occur in the nasal cavity as well. Intestinal-type adenocarcinomas resemble glandular neoplasms that occur in the small and large intestines. The more well-differentiated ones resemble colonic tubular and villous adenomas while those at the other end of the spectrum resemble moderately to poorly-differentiated colonic adenocarcinomas. Others may be composed of goblet cells or resemble colonic mucinous carcinomas. Nonintestinal-type adenocarcinomas are the most diverse of the lot and are composed of adenocarcinomas whose morphologies do not easily fit in into the previous two categories. For purposes of prognostication, they are divided into low-grade and high-grade categories based on architecture, nuclear features and mitotic activity. Low-grade tumors have uniform cells arranged in compact acini, back to back, confluent glands, cystic spaces and papillae. They maintain tall columnar to cuboidal arrangements without much stratification. Cytoplasm is often abundant but variable in appearance – basophilic, granular, mucinous, eosinophilic and also oncocytic. Nuclear atypia is mild to moderate with few mitoses. High-grade tumors are mostly solid, show prominent nuclear pleomorphism, nucleoli and mitotic activitiy. Signet-ring cells may be seen. Necrosis may often be present.2,3,4 We present the case of a 73 year old female with a destructive left nasal cavity mass. Biopsy shows an infiltrative epithelial tumor with a papillary configuration composed of tumor cells draped around vascular cores (Fig. 1 and Fig. 2). High-power view shows cuboidal to polygonal cells that have large, angular and hyperchromatic nuclei without distinct nucleoli. Mitoses are difficult to come by. Cytoplasm is moderate to abundant and has a dense eosinophilic, somewhat oncocytic quality (Fig. 3 and Fig. 4). Mucin-secreting or other intestinal-type cells are not seen. The case was signed out as a low-grade, papillary, nonintestinal-type adenocarcinoma. Unfortunately, the patient was subsequently lost to follow-up. Among patients with intestinal- and nonintestinal-type adenocarcinomas, histologic grade affects outcome. Well-differentiated tumors with predominantly papillary and tubular configurations do better (80% 5-year survival) while poorly differentiated ones do poorly (40% 5-year survival). Recurrences develop in about 50% and distant metastasis in 15%. Overall survival is about 40% with death occurring in approximately 3 years. Treatment is radical surgical resection with post-operative radiotherapy.1

scholarly journals Dermoscopic features of Clear Cell Acanthoma: A Case Report and Review of the Literature

2019 ◽  
Vol 2 (4) ◽  
pp. 96-99
Author(s):  
Moustaide K ◽  
◽  
Aqil N ◽  
Gallouj S ◽  
Mernissi FZ ◽  
...  
Keyword(s):  
Case Report ◽  
Diagnostic Accuracy ◽  
Clear Cell ◽  
Lower Limbs ◽  
Review Of The Literature ◽  
Small Plaque ◽  
Solitary Lesion ◽  
Epithelial Tumor ◽  
Benign Epithelial Tumor

Clear cell acanthoma is an uncommon type of benign epithelial tumor. Typically, it is a solitary lesion found on the lower limbs. It presents as a nodule or small plaque with slow and well-defined growth. Diagnosis used to be clinical and histopathological, but the advent of dermoscopy has led to an increase in diagnostic accuracy. We describe a case in which dermoscopy proved highly useful for diagnosis of the lesion.

Ultrastructural Analysis of the Salivary Glands of Gromphadorhina Portentosa (Schaum)

1977 ◽  
Vol 35 ◽  
pp. 638-639
Author(s):  
P.J. Dailey
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Salivary Glands ◽  
Secretory Vesicles ◽  
The Past ◽  
Transmission Electron ◽  
Means Of Transmission ◽  
Gromphadorhina Portentosa ◽  
Scanning Electron ◽  
Topographical Relief

The structure of insect salivary glands has been extensively investigated during the past decade; however, none have attempted scanning electron microscopy (SEM) in ultrastructural examinations of these secretory organs. This study correlates fine structure by means of SEM cryofractography with that of thin-sectioned epoxy embedded material observed by means of transmission electron microscopy (TEM).Salivary glands of Gromphadorhina portentosa were excised and immediately submerged in cold (4°C) paraformaldehyde-glutaraldehyde fixative1 for 2 hr, washed and post-fixed in 1 per cent 0s04 in phosphosphate buffer (4°C for 2 hr). After ethanolic dehydration half of the samples were embedded in Epon 812 for TEM and half cryofractured and subsequently critical point dried for SEM. Dried specimens were mounted on aluminum stubs and coated with approximately 150 Å of gold in a cold sputtering apparatus.Figure 1 shows a cryofractured plane through a salivary acinus revealing topographical relief of secretory vesicles.

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