Argentaffin Cell

2020 ◽  
Author(s):  
Keyword(s):  
1979 ◽  
Vol 16 (3) ◽  
pp. 292-309 ◽  
Author(s):  
N. F. Cheville

Stomachs of four dogs with uremia and four normal dogs were examined. Uremic stomachs represented four types of disease: atrophic, amyloidotic, ulcerative and necrotic gastropathy. Pathologic changes common to all uremic stomachs were expansion of the lamina propria, atrophy of gastric glands, and submucosal arteriopathy; lesions were limited to body and fundic zones. Lamina propria was markedly expanded by edema, mastocytosis, deposition of acidic mucosubstances, fibroplasia and mineralization. Capillaries in lamina propria had swollen endothelium and calcium salts were present extracellularly as amorphous granular laminae. Gastric glands were distorted and irregular and had fewer cells per unit of tissue. Parietal cells were swollen and had fragmentation of cytocavitary network and mitochondrial swelling with calcification. Chief cells were shrunken, agranular and atrophic with foci of glycogen and dilation of endoplasmic reticulum. Argentaffin cell content was diminished. Muscular arteries of submucosae had segmental degenerative lesions characterized by myocyte necrosis, calcification, and deposition of acidic mucosubstances and fibrin; thrombosis and obstructive arteriopathy were common. These studies suggest that uremic gastropathy is a disease of mucosal lamina propria and that lesions were due to anoxia caused by diffuse vascular injury and to altered parietal cell function.


1936 ◽  
Vol 34 (2) ◽  
pp. 294-299 ◽  
Author(s):  
Charles B. Jones
Keyword(s):  

Nature ◽  
1965 ◽  
Vol 207 (4999) ◽  
pp. 873-874 ◽  
Author(s):  
ELEANOR E. DESCHNER

1966 ◽  
Vol 119 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Robert V. Gregg

Cancer ◽  
1971 ◽  
Vol 28 (4) ◽  
pp. 999-1003 ◽  
Author(s):  
Jun Soga ◽  
Kenji Tazawa ◽  
Osamu Aizawa ◽  
Kanji Wada ◽  
Terukazu Tuto

1955 ◽  
Vol s3-96 (35) ◽  
pp. 295-299
Author(s):  
A. C. CHRISTIE

1. The Kultschitzky cells of the alimentary canal of man and the guinea-pig were studied with the light-microscope, buffered osmium tetroxide being used as fixative. 2. The Kultschitzky cells of the guinea-pig were shown by the electron-microscope to contain spheroidal granules having a maximum diameter of 0.3µ. These granules are considerably darkened by fixation for only 4 hours in 1 % osmium tetroxide solution. 3. The opinion that the granules of the Kultschitzky cell are only an artifact of formaldehyde fixation is denied.


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