scholarly journals Lot or Batch Number Production Identifier

2020 ◽  
Author(s):  
Keyword(s):  
Batch Number

scholarly journals A Case for Regular Aflatoxin Monitoring in Peanut Butter in Sub-Saharan Africa: Lessons from a 3-Year Survey in Zambia

2016 ◽  
Vol 79 (5) ◽  
pp. 795-800 ◽  
Author(s):  
SAMUEL M. C. NJOROGE ◽  
LIMBIKANI MATUMBA ◽  
KENNEDY KANENGA ◽  
MOSES SIAMBI ◽  
FARID WALIYAR ◽  
...  
Keyword(s):  
South Africa ◽  
Aflatoxin B1 ◽  
Peanut Butter ◽  
Aflatoxin Contamination ◽  
Comprehensive Analysis ◽  
Sub Saharan Africa ◽  
Enzyme Linked Immunosorbent Assay ◽  
Contamination Level ◽  
Batch Number ◽  
Sub Saharan

ABSTRACT A 3-year comprehensive analysis of aflatoxin contamination in peanut butter was conducted in Zambia, sub-Saharan Africa. The study analyzed 954 containers of 24 local and imported peanut butter brands collected from shops in Chipata, Mambwe, Petauke, Katete, and Nyimba districts and also in Lusaka from 2012 to 2014. For analysis, a sample included six containers of a single brand, from the same processing batch number and the same shop. Each container was quantitatively analyzed for aflatoxin B1 (AFB1) in six replicates by using competitive enzyme-linked immunosorbent assay; thus, aflatoxin contamination level of a given sample was derived from an average of 36 test values. Results showed that 73% of the brands tested in 2012 were contaminated with AFB1 levels >20 μg/kg and ranged up to 130 μg/kg. In 2013, 80% of the brands were contaminated with AFB1 levels >20 μg/kg and ranged up to 10,740 μg/kg. Compared with brand data from 2012 and 2013, fewer brands in 2014, i.e., 53%, had aflatoxin B1 levels >20 μg/kg and ranged up to 1,000 μg/kg. Of the eight brands tested repeatedly across the 3-year period, none consistently averaged ≤20 μg/kg. Our survey clearly demonstrates the regular occurrence of high levels of AF B1 in peanut butter in Zambia. Considering that some of the brands tested originated from neighboring countries such as Malawi, Zimbabwe, and South Africa, the current findings provide a sub-Saharan regional perspective regarding the safety of peanut butter.

scholarly journals Physicochemical and Microbiological Assays for Quality Evaluation of a Brand of Mentha piperita Tisanes in Costa Rica Market: Employment of the Central American Technical Regulation

2018 ◽  
Vol 8 (5) ◽  
pp. 329-337 ◽  
Author(s):  
Juan José Mora Román ◽  
Natalia Agüero Brenes ◽  
Camila Angulo Morales ◽  
Jose Castro Solís ◽  
Gabriela Hidalgo Carrillo ◽  
...  
Keyword(s):  
Quality Control ◽  
Costa Rica ◽  
Pharmaceutical Products ◽  
Central American ◽  
Mentha Piperita ◽  
Quantitative Composition ◽  
Technical Regulation ◽  
Mentha Spicata ◽  
Mentha Aquatica ◽  
Batch Number

Mentha piperita is a natural hybrid of water mint (Mentha aquatica) and spearmint (Mentha spicata L.), that are consumed as tisanes. For that reason, the present work evaluated physicochemical and microbiological aspects for the quality control of a commercial brand of Mentha piperita herbal tea distributed in Costa Rica, using assays established by the Central American Technical Regulation (RTCA) 11.03.56.09 (Pharmaceutical products. Natural medicinal products for human use. Quality verification), and determined if they have uniformity for different batches of this brand. To verify the quality of three batches of this product, the following assays were done: Labeling requirements, organoleptic, minimum fill, foreign organic matter, loss on drying, total ash, acid-insoluble ash, lead and arsenic limits, microbial enumerations and specific microorganisms (E. coli and Salmonella sp.) assays. As conclusion, the batches were in compliance for all the assays, except for labeling test, since information corresponding to the primary (batch number and expiration date) and secondary packaging (qualitative-quantitative composition of active ingredients interactions and adverse effects) were not presented. Furthermore, one of the batches did not have information about the employment, contraindications and warnings. Also, the manufacturing company maintained a good reproducibility between one batch and another, and the improvements that can be made are in the product labeling and better controls in its filling. Keywords: Natural product, Mentha piperita, quality control, tisane, pharmacopoeia, Central American Technical Regulation.

scholarly journals Physiochemical and Bacteriological Analysis of Selected Sachet Water in Jere and Maiduguri, Borno State Nigeria

2015 ◽  
Vol 4 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Mohammed Modu Aji ◽  
Shettima Abba Kyar ◽  
Mustapha Hussaini
Keyword(s):  
Total Alkalinity ◽  
World Health ◽  
Most Probable Number ◽  
Expiry Date ◽  
Probable Number ◽  
Bacteriological Analysis ◽  
Batch Number ◽  
Registration Number ◽  
Sachet Water

 The study involved the determination of some physiochemical and bacteriological properties in sachet-water samples taken within selected geopolitical wards in Jere and Maiduguri Metropolis. The purpose was to ascertain the quality of sachet water sold for consumption within the area. Ten samples were drawn, five from each study area. The samples were analysed for temperature, colour, turbidity, pH, conductivity, iron, total alkalinity and total dissolved solid. Bacteriological analysis was also carried out using multiple tube (most probable number) technique for enumeration of both total coli form count and differential Escherichia coli count. Other physical examination like volume, National Agency for Food and Drugs Administration and Control (NAFDAC) registration number, batch number, production date and expiry date were also examined. The results obtained were compared with World Health Organization (WHO), NAFDAC and Nigeria Standard of Drinking Water Quality (NSDWQ). Variations were observed among the entire samples in comparison with the standard. Some of the parameters conform to the standard like the Tempreture, pH, colour, odour, iron content and NAFDAC registration number while others like TDS, total alkalinity and volumetric quantity fell below the standard. The bacteriological analysis also showed that 80% of the samples studied revealed the presence of coliforms. Hence, there is need for regulatory agencies like NAFDAC and Standard Organisation of Nigeria (SON) to intensify effort in the routine monitoring of quality of sachet water marketed for consumption.DOI: http://dx.doi.org/10.3126/ije.v4i1.12177 International Journal of Environment Volume-4, Issue-1, Dec-Feb 2014/15, page: 48-57  

Medical management of silicone oil associated acute postoperative ocular inflammation

2021 ◽  
Vol 14 (7) ◽  
pp. e242251
Author(s):  
Mariya Bashir Doctor ◽  
Deepika Chennapura Parameswarappa ◽  
Padmaja Kumari Rani
Keyword(s):  
Medical Management ◽  
Rhegmatogenous Retinal Detachment ◽  
Silicone Oil ◽  
Ocular Inflammation ◽  
Intraocular Inflammation ◽  
Topical Steroids ◽  
Gradual Improvement ◽  
Batch Number ◽  
Oil Injection

We report a case of a 57-year-old man, who underwent right eye silicone oil injection as a part of his surgical treatment for rhegmatogenous retinal detachment. Following this, on the first postoperative day, he developed acute postoperative intraocular inflammation. There was circumciliary congestion, diffuse corneal oedema, anterior chamber (AC) reaction, hypopyon and a pupillary membrane. The AC had not been entered during the surgery. No patients, who had been operated on the same day, or with the materials having the same batch number, developed similar reactions. We started the patient on hourly topical steroids and cycloplegics after which the patient’s condition showed gradual improvement. At the 2 weeks follow-up appointment, his pupillary membrane had completely contracted and the AC was quiet. This case highlights a clinical picture of acute postoperative silicone oil-induced ocular inflammation, which was resolved through medical management.

Blockchain Technology Applied to the Cocoa Export Supply Chain

2020 ◽  
pp. 323-339
Author(s):  
Mario Chong ◽  
Eduardo Perez ◽  
Jet Castilla ◽  
Hernan Rosario
Keyword(s):  
Supply Chain ◽  
Data Structure ◽  
Raw Material ◽  
Expiration Date ◽  
Cocoa Beans ◽  
Batch Number ◽  
Blockchain Technology ◽  
Export Supply ◽  
Production Stages ◽  
Block Chain

This chapter recommends applying block chain technology to the cocoa supply chain. Using this technology, it will be possible to show and guarantee the traceability of the final product. Traceability in the cocoa chain begins in the production stages (harvest and post-harvest) to obtain relevant data related to cocoa beans and their producers, promptly, until finding the raw material origin and inputs used during the process. The material provider's name must be considered, as well as the manufacturer's expiration date, the batch number, and the production area's reception date. This is why authors recommend using Block chain, which is a data structure that stores information chronologically in interlinked blocks. It works as a digital master book and the participants reach an agreement to register any information in the blocks. Throughout the chapter, authors show how to apply this technology.

scholarly journals Bacteriological Assessment of Bottled Drinking Water Available at Major Transit Places in Mangalore City of South India

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Nitin Joseph ◽  
Sevitha Bhat ◽  
Subhani Mahapatra ◽  
Ayush Singh ◽  
Sajal Jain ◽  
...  
Keyword(s):  
Drinking Water ◽  
Human Life ◽  
Viable Count ◽  
Bottled Water ◽  
National Standards ◽  
Ozone Treatment ◽  
Floating Bodies ◽  
Long Distance ◽  
Batch Number

Introduction. Safe drinking water is essential for human life. It is generally considered that bottled water is safe for usage by people. For long-distance travelers, it serves as the only source of reliable drinking water. But, several studies have reported that bottled water does not always meet the acceptability standards. Objectives. To assess the bacteriological and physical quality of bottled water marketed in major transit areas and to check its compliance with national standards. Methods. The investigating team visited retail shops at three main transit sites for long-distance travelers in Mangalore city. A total of 24 water bottles of 12 brands were randomly selected. The analysis of total viable count (TVC) was done to assess the bacteriological quality of samples. Results. In 3(12.5%) samples, all of which were of local brands, batch number, the period of manufacture, and the period of expiry were not mentioned. Odor and floating bodies were present in one sample each. Five (20.8%) water bottles had been enriched with minerals. Ozone treatment was the most commonly 22(91.7%) used method for disinfection of water. In only 15(62.5%) samples, the bacterial contamination was within acceptable limits certified for drinking purposes. Water samples manufactured by multinational companies (p=0.018), those with batch number mentioned (p=0.042), the best period of manufacture (p=0.036), and long expiry dates (p=0.028) were acceptable for usage. Conclusion. Surveillance of bottled water manufacturing industries in the settings on a regular basis needs to be done by regulatory agencies. These measures will ensure safe and wholesome bottled water for public usage.

scholarly journals Evaluation of Bis (2-ethylhexyl) phthalate (DEHP) in the PET Bottled Mineral Water of Different Brands and Impact of Heat by GC-MS/MS

2021 ◽  
Author(s):  
Laxmi Kant Bhardwaj ◽  
Archana Sharma
Keyword(s):  
Storage Time ◽  
Mineral Water ◽  
Storage Conditions ◽  
Gas Chromatography Mass Spectrometry ◽  
Local Market ◽  
Batch Number ◽  
Water Filling ◽  
And Storage ◽  
Ethylhexyl Phthalate ◽  
Bottled Mineral Water

Abstract Phthalates are one of the ubiquitous contaminants in the environment due to the extensive use in the last few years. They are easily released because they are not chemically bonded to polymers. They migrate into the food during food packing while in water, they migrate during water filling or storage and bottle manufacturing. They are toxic to human health and known as carcinogen/ endocrine disruptors. A total of sixty PET (polyethylene terephthalate) bottled mineral water samples of different six brands were purchased from the local market of Noida, India. These bottles were of two different batch numbers of each brand. Two bottles of each brand with a different batch number were analyzed immediately after purchase while the other eight bottles were analyzed after two and six months when they were stored in sunlight (~ 45 o C) and - 20 o C. The aim of the present study was to determine the migration of DEHP and its impact on storage conditions of PET bottled mineral water in retail stores or homes. We used a gas chromatography-mass spectrometry (GC-MS/MS) for the estimation of DEHP in these samples. We observed that the migration of DEHP was dependent on high temperature and storage time. DEHP was present only in those samples, which were stored in sunlight for two & six months and at - 20 o C for six months. While found below the detection limit in those samples which were analyzed immediately after purchase and stored at - 20 o C for two months.

scholarly journals Identification of health and safety management system components in the fish patty production

2019 ◽  
Vol 81 (1) ◽  
pp. 105-111
Author(s):  
N. I. Dunchenko ◽  
M. S. Hadgu ◽  
E. S. Voloshina ◽  
V. S. Yankovskaya ◽  
S. V. Kuptsova ◽  
...  
Keyword(s):  
Management System ◽  
Safety Management ◽  
Health And Safety ◽  
Control Points ◽  
Expiry Date ◽  
Safety Management System ◽  
Batch Number ◽  
Critical Control Points ◽  
System Components ◽  
Fish Patty

The article reveals research on the development of health and safety management system components for making fish patties from different species of shark catfish (Pangasianodon Hypophthalmus), croaker (Otolithus Sp), silver carp (Hypophthalmichthys Molitrix), Atlantic mackerel (Scomber Scombrus) and lizardfish (Saurida Tumbil). It suggests a nomenclature of fish patty safety indicators including hygienic, microbiological, identificational, and also the product list, ingredients, organoleptic properties, physical and chemical properties, nutritional energy value, date of manufacture and date of packaging, expiry date and storage conditions, batch number, conformity markings, name and location of the manufacturer. The research has analyzed the fish patty production block diagram and determined critical control points. Based on the cause and effect diagram for defects in fish patties, all defects are grouped into three blocks: defects due to the poor quality of raw material, processing defects, defects due to improper storage, transportation and sale. The obtained results have underlain the guidelines to prevent defective products at the stages of acceptance, manufacture, storage, and transportation of products to the consumer. The research also communicates recommendations for procurement of raw materials, production control, and qualification requirements for personnel, labor protection and metrological control of the equipment used. HACCP components have been successfully identified: preventive measures for hazards identified in the production of fish patties, 6 critical control points, a draft HACCP plan, and a prerequisite program.

scholarly journals P037 Evaluating the introduction of dose banded cefotaxime using pre- filled syringes, for early onset sepsis on a neonatal unit

2019 ◽  
Vol 104 (7) ◽  
pp. e2.42-e2
Author(s):  
Suzannah Hibberd
Keyword(s):  
Early Onset ◽  
Electronic Prescribing ◽  
Drug Preparation ◽  
List Type ◽  
Nice Guideline ◽  
Batch Number ◽  
Early Onset Sepsis ◽  
Mandatory Requirement ◽  
Group A ◽  
Group B

BackgroundIn December 2017, cefotaxime doses for treatment of early onset sepsis were banded according to weight. The dose-banding only applies to neonates <7 days old. The implementation of pre-filled syringes (PFS) supplied by the Pharmacy Technical Services Unit coincided with the introduction of cefotaxime dose-banding.AimTo assess whether cefotaxime is prescribed according to the dose-banding guideline. To establish if batch numbers of PFS are reconciled on the electronic prescribing system (EPS). To determine whether introducing PFS has resulted in more neonates receiving the first dose of antibiotics within 1 hour of the decision to treat.MethodsAn EPS report was generated for 2 groups of patients. Group A received cefotaxime from April to June 2018, group B received cefotaxime from September to November 2017, before dose-banding was introduced. Data collected included: weight; dose; time of prescribing and time of administration for the first dose; whether a PFS was used and if the batch number was reconciled electronically. Patients transferred into the unit were excluded as they had started their antibiotics prior to transfer.Results95.3% of group A, (n=85), received doses in accordance with the guideline, two doses were prescribed according to weight. Out of the 95.3% eligible to receive PFS, 91.4% of PFS were documented on the EPS. It was unknown whether PFS were used for the remaining patients. 90.5% of the PFS batch numbers were reconciled, 8.1% were not reconciled and 1.4% had incomplete records. 81.2% of group A received the first dose of antibiotics ≤60 minutes from the point of prescribing in comparison to 76.6% in group B (n=94). 58.8% of group A and 42.6% of group B had doses administered ≤30 minutes after prescribing. Both groups had 5 patients that did not receive their first dose until >2 hours after prescribing.ConclusionThe majority of prescribers are using the dose- banding guideline. 91.4% of doses have been administered using PFS, thereby reducing nursing time used for IV drug preparation. In 8.6% it could not be determined whether a PFS was used although prescription templates had been used. The template includes a mandatory box to say if a PFS has been used, nurses cannot sign the drug administration if it is empty. An outcome from this study is that this discrepancy will be investigated by the electronic prescribing team. Nurses are recording batch numbers onto the EPS in 90.5% of cases. Nurses will be reminded to reconcile batch numbers and making it a mandatory requirement on the EPS will be investigated Having PFS available has led to more patients receiving their dose within 30 minutes and slightly more receiving their doses within 60 minutes. However similar numbers are still receiving their doses >60 minutes after prescribing. Next steps will be to examine cases where antibiotics are delayed and identify causes. A limitation of this study is that it does not take into account how long it takes the prescriber to write the prescription after making the decision to treat.ReferenceNational Institute for Health and Clinical Excellence. ( 2012) Neonatal Infection (early onset): antibiotics for prevention and treatment. NICE Guideline (CG149)

Effects of scorpion venom on electrolyte transport by rabbit ileum

1983 ◽  
Vol 244 (5) ◽  
pp. G501-G506 ◽  
Author(s):  
K. A. Hubel
Keyword(s):  
Ion Transport ◽  
Short Circuit ◽  
Muscularis Propria ◽  
Short Circuit Current ◽  
Chloride Secretion ◽  
Scorpion Venom ◽  
Tissue Response ◽  
Flux Chamber ◽  
Rabbit Ileum ◽  
Batch Number

Scorpion venom, which depolarizes nerves, was used to obtain further evidence that intramural nerves affect ion transport by the rabbit ileum. Ileal epithelium, stripped of muscularis propria, was mounted in a flux chamber modified to permit electrical field stimulation (EFS) of the tissue. Response of the short-circuit current (Isc) to venom was most rapid on the serosal surface, and the response was eliminated by tetrodotoxin. Isc response was influenced by venom batch number and by factors within the tissue. Venom (10 micrograms/ml) and EFS each caused chloride secretion by reducing mucosal-to-serosal movement and by increasing serosal-to-mucosal movement. Sodium transport and residual ion fluxes did not change. In the presence of venom, EFS caused no further changes in ion transport, but tissues still responded to glucose and to aminophylline. The early peak of Isc was reduced about 40% by atropine, implying that acetylcholine, released by venom, stimulates muscarinic receptors. The blockade of the Isc response to venom with tetrodotoxin is further evidence that venom depolarizes intramural nerves and liberates transmitters that cause chloride secretion. The identity of the other transmitters is not known.

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