scholarly journals Polyamine Catabolism

2020 ◽  
Author(s):  
Keyword(s):  
Polyamine Catabolism

scholarly journals Metabolomics Reveals Aging-associated Attenuation of Noninvasive Radiation Biomarkers in Mice: Potential Role of Polyamine Catabolism and Incoherent DNA Damage-repair

2013 ◽  
Vol 12 (5) ◽  
pp. 2269-2281 ◽  
Author(s):  
Soumen K. Manna ◽  
Kristopher W. Krausz ◽  
Jessica A. Bonzo ◽  
Jeffrey R. Idle ◽  
Frank J. Gonzalez
Keyword(s):  
Dna Damage ◽  
Potential Role ◽  
Dna Damage Repair ◽  
Polyamine Catabolism ◽  
Damage Repair

Polyamine catabolism: target for antiproliferative therapies in animals and stress tolerance strategies in plants

Amino Acids ◽  
2011 ◽  
Vol 42 (2-3) ◽  
pp. 411-426 ◽  
Author(s):  
Paraskevi Tavladoraki ◽  
Alessandra Cona ◽  
Rodolfo Federico ◽  
Giampiero Tempera ◽  
Nikenza Viceconte ◽  
...  
Keyword(s):  
Stress Tolerance ◽  
Polyamine Catabolism

Acetylation of spermidine in polyamine catabolism

1980 ◽  
Vol 633 (2) ◽  
pp. 181-190 ◽  
Author(s):  
N. Seiler ◽  
F.N. Bolkenius ◽  
B. Knödgen
Keyword(s):  
Polyamine Catabolism

Ethylene triggers salt tolerance in maize genotypes by modulating polyamine catabolism enzymes associated with H 2 O 2 production

2018 ◽  
Vol 145 ◽  
pp. 75-86 ◽  
Author(s):  
Valdineia Soares Freitas ◽  
Rafael de Souza Miranda ◽  
José Hélio Costa ◽  
Daniel Farias de Oliveira ◽  
Stelamaris de Oliveira Paula ◽  
...  
Keyword(s):  
Salt Tolerance ◽  
Polyamine Catabolism ◽  
Maize Genotypes

Polyamine catabolism is involved in response to salt stress in soybean hypocotyls

2011 ◽  
Vol 168 (11) ◽  
pp. 1234-1240 ◽  
Author(s):  
María Paula Campestre ◽  
Cesar Daniel Bordenave ◽  
Andrea Cecilia Origone ◽  
Ana Bernardina Menéndez ◽  
Oscar Adolfo Ruiz ◽  
...  
Keyword(s):  
Salt Stress ◽  
Polyamine Catabolism

Polyamine Catabolism in Relation to Trypsin Activation and Apoptosis in Experimental Acute Pancreatitis

Pancreatology ◽  
2011 ◽  
Vol 11 (2) ◽  
pp. 83-91 ◽  
Author(s):  
Hai-Tao Jin ◽  
Teemu Lämsä ◽  
Panu H. Nordback ◽  
Mervi T. Hyvönen ◽  
Sari Räty ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Experimental Acute Pancreatitis ◽  
Polyamine Catabolism

Inflammation and polyamine catabolism: the good, the bad and the ugly

2007 ◽  
Vol 35 (2) ◽  
pp. 300-304 ◽  
Author(s):  
N. Babbar ◽  
T. Murray-Stewart ◽  
R.A. Casero
Keyword(s):  
Cell Growth ◽  
Cell Types ◽  
Tumour Cells ◽  
Good Effect ◽  
Relative Role ◽  
Infectious Agents ◽  
Inflammatory Stress ◽  
Polyamine Catabolism ◽  
Polyamine Analogues ◽  
Mediators Of Inflammation

The induction of polyamine catabolism by specific anti-tumour polyamine analogues has increased interest in the roles polyamine catabolism play in cell growth, death and response to various anti-tumour agents. The relatively recent finding of an inducible mammalian spermine oxidase (SMO/PAOh1), in addition to the two-step spermidine/spermine N1-acetyltransferanse (SSAT)/N1-acetylpolyamine oxidase (APAO) catabolic pathway, underscores the complexities of the regulation of polyamine catabolism by various stimuli. Furthermore, recent data indicate that infectious agents and mediators of inflammation can also up-regulate polyamine catabolism. Induction of SSAT by these agents can reduce intracellular polyamine concentrations and cell growth rate, thus providing a beneficial mechanism by which cells may adapt to inflammatory stress. However, increased polyamine catabolism can also result in substantial increases in intracellular reactive oxygen species (ROS) through the production of H2O2 as a by-product of either APAO or SMO/PAOh1 activity. This increased generation of ROS can have different results, depending on the mechanism of induction and cell types involved. Targeted killing of tumour cells by agents that stimulate SSAT/APAO and/or SMO/PAOh1 is obviously a ‘good’ effect. However, induction of SMO/PAOh1 by inflammation or infectious agents has the potential to produce sufficient ROS in normal, non-tumour cells to lead to DNA damage, mutation and, potentially, carcinogenic transformation (‘bad’). The variation in the induction of these polyamine catabolic enzymes, as well as the level and timing of this induction will dictate the cellular outcome in the presence of both desirable and undesirable effects (‘ugly’). Here we discuss the relative role of each of the steps in polyamine catabolism in response to inflammatory stress.

scholarly journals Activated Polyamine Catabolism in Acute Pancreatitis

2006 ◽  
Vol 168 (1) ◽  
pp. 115-122 ◽  
Author(s):  
Mervi T. Hyvönen ◽  
Karl-Heinz Herzig ◽  
Riitta Sinervirta ◽  
Elke Albrecht ◽  
Isto Nordback ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Polyamine Catabolism

Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N 1 , N 11 diethylnorspermine

2007 ◽  
Vol 62 (3) ◽  
pp. 517-527 ◽  
Author(s):  
Suzanne Hector ◽  
Ramakumar Tummala ◽  
Nicholas D. Kisiel ◽  
Paula Diegelman ◽  
Slavoljub Vujcic ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Cells ◽  
Polyamine Catabolism ◽  
Colorectal Cancer Cells
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