scholarly journals Immunoradiometric Assay

2020 ◽  
Author(s):  
Keyword(s):  
Immunoradiometric Assay

An Immunoradiometric Assay for Factor VIII Related Antigen (VIIIRAg) Using Two Monoclonal Antibodies-Comparison with Polyclonal Rabbit Antibodies for Use in von Willebrand’s Disease Diagnosis

1984 ◽  
Vol 52 (03) ◽  
pp. 250-252 ◽  
Author(s):  
Y Sultan ◽  
Ph Avner ◽  
P Maisonneuve ◽  
D Arnaud ◽  
Ch Jeanneau
Keyword(s):  
Monoclonal Antibodies ◽  
Structural Changes ◽  
Polyclonal Antibodies ◽  
Disease Diagnosis ◽  
Immunoradiometric Assay ◽  
Von Willebrand's Disease ◽  
Von Willebrand’S Disease ◽  
Structural Abnormalities ◽  
Antigenic Material ◽  
Von Willebrand

SummaryTwo monoclonal antibodies raised against FVIII/von Willebrand protein were used in an immunoradiometric assay (IRMA) to measure this antigen in normal plasma and plasma of patients with different forms of von Willebrand’s disease. The first antibody, an IgG1 was used to coat polystyrene tubes, the second one, an IgG2a, iodinated and used in the second step. Both antibodies inhibit ristocetin induced platelet agglutination and react strongly with platelets, megacaryocytes and endothelial cells. The IRMA test using these antibodies showed greater sensitivity than that using rabbit polyclonal anti VIIIRAg antibodies. A good correlation between the two tests was nevertheless found when VIIIRAg was measured in the majority of patient’s plasma. However 5 patients from 3 different families showed more antigenic material in the rabbit antibody IRMA than in the monoclonal antibody IRMA. It is suggested therefore that the monoclonal antibodies identify part of the VIIIR:Ag molecule showing structural abnormalities in these vWd patients, these structural changes remaining undetected by the polyclonal antibodies.

Application of an immunoradiometric assay for thyrotrophin in evaluation of thyroidal and nonthyroidal disease states

Pathology ◽  
1987 ◽  
Vol 19 (3) ◽  
pp. 229-232 ◽  
Author(s):  
Graham H. McLellan ◽  
W.J. Riley ◽  
Margaret B. Summers ◽  
Paul Sudholz ◽  
Peter E. Hickman
Keyword(s):  
Immunoradiometric Assay ◽  
Disease States

Double antibody immunoradiometric assay of hGH employing a terminal labeling technique

1982 ◽  
Vol 9 (4) ◽  
pp. 271-275 ◽  
Author(s):  
Ata Gokce ◽  
Robert M. Nakamura ◽  
Timothy J. O.'Brien ◽  
Manuel Tubis ◽  
Walter Wolf
Keyword(s):  
Immunoradiometric Assay ◽  
Double Antibody

HBeAg/Anti-HBe Determination with a New Monoclonal Immunoradiometric Assay

Vox Sanguinis ◽  
1985 ◽  
Vol 48 (3) ◽  
pp. 129-135
Author(s):  
G. Pizzocolo ◽  
D. Giammatteo ◽  
U. Barbieri ◽  
A. Boniolo ◽  
L. Callegaro ◽  
...  
Keyword(s):  
Immunoradiometric Assay

scholarly journals A Novel Immunoradiometric Assay Detects Full-Length Human PTH but not Amino-Terminally Truncated Fragments: Implications for PTH Measurements in Renal Failure

1999 ◽  
Vol 84 (11) ◽  
pp. 4287-4290 ◽  
Author(s):  
Markus R. John ◽  
William G. Goodman ◽  
Ping Gao ◽  
Tom L. Cantor ◽  
Isidro B. Salusky ◽  
...  
Keyword(s):  
Renal Failure ◽  
Full Length ◽  
Immunoradiometric Assay

Application of novel magnetizable cellulose particles in the development of immunoradiometric assay for C-peptide

2015 ◽  
Vol 304 (3) ◽  
pp. 1115-1122 ◽  
Author(s):  
R. R. Rasmi ◽  
K. Bhasker Shenoy ◽  
V. B. Kadwad ◽  
Jayula Sarnaik ◽  
H. M. Somashekarappa
Keyword(s):  
Immunoradiometric Assay ◽  
C Peptide
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