Proximal Part of the Lumen of the Centriole

2020 ◽  
Author(s):  
Keyword(s):  
Proximal Part

Possibility of simultaneous transposition of segments of the pectoralis major muscle to restore flexion in the shoulder and elbow joints (clinical observation)

MedAlliance ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 61-68
Keyword(s):  
Anterior Part ◽  
Pectoralis Major Muscle ◽  
Elbow Flexion ◽  
Functional Results ◽  
Proximal Part ◽  
Deltoid Muscle ◽  
Pectoralis Major ◽  
Orthopedic Surgeons ◽  
Active Function ◽  
Head Neck

The pectoralis major is a widely used muscle in reconstruction surgery for replacement soft tissue defects of a head, neck, thorax, upper limbs and restoration of muscle active function. The peculiarities of anatomy of the pectoralis major makes it possible to divide the muscle into several segments with their own innervations and supply and use them independently from each other. This article describes the anatomy of the pectoralis major and the opportunity for clinical applications of different segments of this muscle. The authors demonstrate the result of the restoration of shoulder and elbow flexion in a patient with arthrogryposis due to simultaneous transfer of the proximal part of pectoralis major to the anterior part of the deltoid muscle and the distal part of pectoralis major to the biceps with good functional results. The article will be useful for plastic surgeons, orthopedic surgeons and physiotherapists.

scholarly journals Stratigraphic revision and reconstruction of the deep-sea fan of the Voirons Flysch (Voirons Nappe, Chablais Prealps)

2021 ◽  
Vol 114 (1) ◽  
Author(s):  
Jérémy Ragusa ◽  
Lina Maria Ospina-Ostios ◽  
Pascal Kindler ◽  
Mario Sartori
Keyword(s):  
Deep Sea ◽  
Distal Part ◽  
Accretionary Prism ◽  
Proximal Part ◽  
Late Eocene ◽  
Lithostratigraphic Units ◽  
Stratigraphic Record ◽  
Sea Fan ◽  
Stratigraphic Evolution ◽  
Depositional Setting

AbstractThe Voirons Flysch (Caron in Eclogae Geologicae Helvetiae 69:297–308, 1976), is a flysch sequence aggregated into the sedimentary accretionary prism of the Chablais and Swiss Prealps. Its palaeogeographic location is still debated (South Piemont or Valais realm). We herein present a stratigraphic revision of the westernmost unit of the former Gurnigel Nappe sensu Caron (Eclogae Geologicae Helvetiae 69:297–308, 1976): the Voirons Flysch. This flysch is subdivided into three lithostratigraphic units at the formation level (the Voirons Sandstone, the Vouan Conglomerate, the Boëge Marl), with an additional unit (Bruant Sandstone) of uncertain attribution, ranging from the early Eocene to probably the late Eocene. We further propose a new model of the depositional setting of the deep-sea of the Voirons Flysch based on palaeocurrent directions, the overall geometry and sedimentary features. This model depicts an eastward deflected deep-sea fan. The stratigraphic record of the proximal part of this fan is fairly complete in the Voirons area, whereas its most distal part is only represented by one small exposure of thinly bedded sandstones in the Fenalet quarry. The stratigraphic evolution of the Voirons Flysch shows two major disruptions of the detrital sedimentation at the transition between Voirons Sandstone—Vouan Conglomerate and Vouan Conglomerate—Boëge Marl. The cause of these disturbances has to be constrained in the framework of the palaeogeographic location of the Voirons Flysch.

Frozen elephant trunk infection: to defrost or to debranch?

2020 ◽  
Author(s):  
Joseph Nader ◽  
Yuthiline Chabry ◽  
Houda Nazih ◽  
Thierry Caus
Keyword(s):  
Proximal Part ◽  
Acute Type ◽  
Frozen Elephant Trunk ◽  
Elephant Trunk ◽  
Aortic Arch Replacement ◽  
Descending Aorta ◽  
Type A Aortic Dissection ◽  
Hybrid Prosthesis

Abstract Infections of frozen elephant trunk hybrid prosthesis (HP) are not well documented in the literature and their management is not standardized yet. We report herein the case of a 59-year-old patient who benefited from a Thoraflex™ HP aortic arch replacement for an acute type A aortic dissection. He presented a year later with a Staphylococcus aureus infection of the proximal part of this prosthesis. We performed a replacement of the proximal compound of the HP accompanied by a complete debranching of the 3 supra-aortic vessels with an inter-carotidal retro-oesophageal bypass. As we left in situ the endovascular graft within the descending aorta, a life-long antibiotic therapy was introduced. The postoperative follow-up was uneventful, and the patient discharged home 2 weeks after his surgery. As an alternative to a more radical redo surgery with major risk, a hybrid medical and surgical treatment of infected frozen elephant trunk could be considered.

scholarly journals Focused Genetic Recombination of Bacteriophage T4 Initiated by Double-Strand Breaks

Genetics ◽  
2002 ◽  
Vol 162 (2) ◽  
pp. 543-556
Author(s):  
Victor Shcherbakov ◽  
Igor Granovsky ◽  
Lidiya Plugina ◽  
Tamara Shcherbakova ◽  
Svetlana Sizova ◽  
...  
Keyword(s):  
Genetic Recombination ◽  
Bacteriophage T4 ◽  
Proximal Part ◽  
Coupling Model ◽  
Strand Break ◽  
Double Strand Breaks ◽  
Strand Breaks ◽  
The Right ◽  
Frequency Distance

Abstract A model system for studying double-strand-break (DSB)-induced genetic recombination in vivo based on the ets1 segCΔ strain of bacteriophage T4 was developed. The ets1, a 66-bp DNA fragment of phage T2L containing the cleavage site for the T4 SegC site-specific endonuclease, was inserted into the proximal part of the T4 rIIB gene. Under segC+ conditions, the ets1 behaves as a recombination hotspot. Crosses of the ets1 against rII markers located to the left and to the right of ets1 gave similar results, thus demonstrating the equal and symmetrical initiation of recombination by either part of the broken chromosome. Frequency/distance relationships were studied in a series of two- and three-factor crosses with other rIIB and rIIA mutants (all segC+) separated from ets1 by 12-2100 bp. The observed relationships were readily interpretable in terms of the modified splice/patch coupling model. The advantages of this localized or focused recombination over that distributed along the chromosome, as a model for studying the recombination-replication pathway in T4 in vivo, are discussed.

Pathomorphological study on gastroduodenal ulceration in horses: Localisation of lesions

2007 ◽  
Vol 55 (2) ◽  
pp. 241-249 ◽  
Author(s):  
Barbora Bezdekova ◽  
P. Jahn ◽  
M. Vyskocil
Keyword(s):  
Single Case ◽  
Proximal Part ◽  
Gastric Ulcers ◽  
Squamous Mucosa ◽  
Oesophageal Ulceration ◽  
Prevalent Disease ◽  
Greater Curvature ◽  
Gastroduodenal Ulceration ◽  
Lesser Curvature ◽  
Low Prevalence

Gastroduodenal ulceration is a prevalent disease in foals and adult horses. Decreased performance as well as fatal complications relate to this syndrome. The objective of our study was to determine the prevalence of gastric ulceration in a mixed population of horses by postmortem examination and to evaluate a possible association between equine gastric ulcer syndrome (EGUS) and sex or age of the examined horses, to evaluate the localisation of lesions in the proximal part of the gastrointestinal tract and to determine the occurrence of gastric parasites. Post-mortem examinations were performed on 71 horses over a period of 24 months. Gastric ulcers were found in 52 horses (73.2%). There was no significant association between age or sex and occurrence of gastric ulcers. In all horses the squamous mucosa lesions were localised near the margo plicatus (100% of the cases), whereas in 23 horses the lesions were near the margo plicatus and lesser curvature and in 7 horses at the greater curvature. In 18 horses the mucosa was affected in the whole extent of the margo plicatus and in 1 horse diffuse lesions of the squamous mucosa were noted. Lesions of the glandular mucosa were localised in 11 horses at the fundic area, in 1 horse they occurred in the pylorus, and in 10 horses diffuse lesions of the glandular mucosa were recorded. A low prevalence of Gasterophilus intestinalis infection was detected (1 horse, 1.4%). We have confirmed that gastric ulcers are a common problem in horses and duodenal or oesophageal ulceration is rare (not a single case of the latter was found in this study). Lesions in the glandular mucosa of the stomach are more frequent in suckling foals than in older animals. Lesions of the glandular mucosa are also common in adult horses, and a complete gastroscopic examination including examination of the pylorus is advisable to evaluate this syndrome.

P2736Hemodynamic and clinical impact in adult patients with anomalous aortic origin of the coronary artery evaluated with quantitative flow reserve

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
J Adjedj ◽  
F Hyafil ◽  
F Aminfar ◽  
A Farnoud ◽  
V Rubimbura ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery ◽  
Clinical Decision Making ◽  
Quantitative Coronary Angiography ◽  
Proximal Part ◽  
Clinical Impact ◽  
Adult Patients ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Quantitative Flow

Abstract Background Anomalous origin of the right coronary artery (ARCA) represents the most frequent form of abnormal coronary origin and may potentially increase the risk for sudden cardiac death. Evaluation of ARCA in adult patients referred for invasive coronary angiograms (ICA) is difficult, and clinical impact is unknown. Quantitative flow reserve (QFR) is an available method able to virtually calculate fractional flow reserve using 3-dimensional quantitative coronary angiography (3D-QCA) based on ICA. Objectives To evaluate the feasibility of QFR analysis in patients with ARCA and its clinical impact. Methods Using the registry of proximal anomalous connections of coronary arteries (ANOCOR registry), a multicentric observational registry including 472 adult patients with ANOCOR between 2010 and 2013, we retrospectively performed QFR analysis from ICA and evaluated the rate of death, myocardial infarction, unplanned revascularization and hospitalization in cardiology at 5 years. Results Among 128 patients with ARCA, 41 (32%) could have QFR analysis with median clinical follow-up of 8.3 years. The mean QFR value was 0.90±0.10, and 3D-QCA analysis showed preserved lumen area despite the elliptical shape of the proximal part of the ARCA which in the worst cases appeared on ICA as a significant narrowing. The event rate was 14.6% (n=6), including three deaths (one due to cancer, one due to stroke, and one cause remains unknown), two unplanned revascularizations, and one hospitalization for heart failure at 5 years. No myocardial infarction was reported. Conclusions QFR analysis of ARCA is feasible and non-significant QFR values are associated with good clinical outcome at 5 years. QFR of ARCA could be the evaluation of choice to help in clinical decision-making during ICA, when applicable.

scholarly journals Temporal and spatial changes in wall shear stress during atherosclerotic plaque progression in mice

2018 ◽  
Vol 5 (3) ◽  
pp. 171447 ◽  
Author(s):  
R. Xing ◽  
A. M. Moerman ◽  
Y. Ridwan ◽  
M. J. Daemen ◽  
A. F. W. van der Steen ◽  
...  
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Mouse Model ◽  
Atherosclerotic Plaque ◽  
Proximal Part ◽  
Plaque Progression ◽  
Plaque Composition ◽  
Spatial Changes ◽  
Temporal And Spatial ◽  
Wall Shear

Wall shear stress (WSS) is involved in atherosclerotic plaque initiation, yet its role in plaque progression remains unclear. We aimed to study (i) the temporal and spatial changes in WSS over a growing plaque and (ii) the correlation between WSS and plaque composition, using animal-specific data in an atherosclerotic mouse model. Tapered casts were placed around the right common carotid arteries (RCCA) of ApoE −/− mice. At 5, 7 and 9 weeks after cast placement, RCCA geometry was reconstructed using contrast-enhanced micro-CT. Lumen narrowing was observed in all mice, indicating the progression of a lumen intruding plaque. Next, we determined the flow rate in the RCCA of each mouse using Doppler Ultrasound and computed WSS at all time points. Over time, as the plaque developed and further intruded into the lumen, absolute WSS significantly decreased. Finally at week 9, plaque composition was histologically characterized. The proximal part of the plaque was small and eccentric, exposed to relatively lower WSS. Close to the cast a larger and concentric plaque was present, exposed to relatively higher WSS. Lower WSS was significantly correlated to the accumulation of macrophages in the eccentric plaque. When pooling data of all animals, correlation between WSS and plaque composition was weak and no longer statistically significant. In conclusion, our data showed that in our mouse model absolute WSS strikingly decreased during disease progression, which was significantly correlated to plaque area and macrophage content. Besides, our study demonstrates the necessity to analyse individual animals and plaques when studying correlations between WSS and plaque composition.

THE SEED PRODUCTION CAPACITY AND EFFICIENCY OF RED PINE CONES (PINUS RESINOSA AIT.)

1956 ◽  
Vol 34 (1) ◽  
pp. 27-36 ◽  
Author(s):  
L. A. Lyons
Keyword(s):  
Seed Production ◽  
Production Efficiency ◽  
Production Capacity ◽  
Pinus Resinosa ◽  
Proximal Part ◽  
Red Pine ◽  
First Year ◽  
Tree Crown ◽  
Second Year ◽  
Pine Cones

The seed capacity of red pine cones varies from about 30 to over 110, depending on the size of the cone and its position in the tree crown, and is determined by the number of ovules that are structurally complete at the time of pollination. These ovules occur in a central "productive" region and constitute less than one-half of the total. The remaining ovules, most: of which are in the proximal part of the cone, never become structurally perfect, and do not contribute to seed production. Abortion of ovules in the productive region usually reduces seed production efficiency to 50–60%, and is accompanied mainly by withering of the nucellus in the first year and failure to produce archegonia early in the second year. The extent of ovule abortion during the first year varies indirectly with cone size, seed capacity, and height in tree.

A new muscle receptor organ in the antenna of the rock lobster Palinurus vulgaris : mechanical, muscular and proprioceptive organization of the two proximal joints J0 and J1

1983 ◽  
Vol 218 (1210) ◽  
pp. 95-110 ◽  
Keyword(s):  
Anterior Part ◽  
Proximal Part ◽  
The Other ◽  
Chordotonal Organ ◽  
Excitatory Postsynaptic Potentials ◽  
Rock Lobster ◽  
Postsynaptic Potentials ◽  
Muscle Receptor ◽  
Physiological Properties ◽  
Receptor Organ

(i) Following previous work on the morphological and physiological properties of the two distal joints (J2, J3) of the atenna of the rock lobster Palinurus vulgaris , the mechanical, muscular and proprioceptive organization of the two proximal joints between the antennal segments S1 and S2 (J1) and between S1 and the cephalothorax (J0) have now been studied. (ii) Articulated by two classical condyles, J1 moves in a mediolateral plane. One external rotator muscle (ER) and three internal rotator muscles (IR1, IR2, IR3) subserve its movements. J0 is articulated by two different systems: a classical ventrolateral condyle and a complex sliding system constituted by special cuticular structures on the dorsomedial side of the S1 segment and on the rostrum between the two antennae. J0 moves in the dorsoventral plane by means of a levator muscle (Lm) and a depressor muscle (Dm). A third muscle, the lateral tractor muscle (LTm), associated with J0 and lying obliquely across S1, may modulate the level of friction between the S1 segment and the rostrum. (iii) Proprioception in J1 is achieved by a muscle receptor organ AMCO-J1 (antennal myochordotonal organ for the J1 joint) associating a small accessory muscle (S1.am) located in the proximal part of the S1 segment and a chordotonal organ inserted proximally on the S1.am muscle and distally on the S2 segment. J0 proprioception is ensured by a simple chordotonal organ (CO-J0) located in the anterior part of the cephalothorax. (iv) The S1.am muscle is innervated by three motoneurons characterized by their very small diameters and inducing respectively tonic excitatory postsynaptic potentials, phasic excitatory postsynaptic potentials and inhibitory postsynaptic potentials. Anatomical and physiological observations suggest functional correlation between S1.am and IR1 motor innervation. (v) Mechanical and muscular organization of J0 and J1 are compared with that of the other joints of the antenna. The properties of the AMCO-J1 proprioceptor are discussed in relation to the other muscle receptor organs described in crustaceans.

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