Primary Peritoneal Serous Borderline Tumor/ Primary Peritoneal Atypical Proliferative Serous Tumor

2020 ◽  
Author(s):  
2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Cristina Ferreira ◽  
João Fraga ◽  
Célia Antunes ◽  
Manuela Gonçalo ◽  
Paulo Donato

Ovarian cancer is the most fatal gynecologic malignancy. The incidence of ovarian cancer among female-to-male transsexuals receiving treatment with testosterone is unknown, and few cases have been reported in the literature. We report a recent case in our institution, a 23-year-old female-to-male transsexual patient who received testosterone supplementation. The patient underwent a pelvic magnetic resonance imaging to study an ovarian complex cyst that revealed the presence of a bilateral ovarian tumor with imaging features of borderline serous tumor. These masses were surgically removed and the pathology report confirmed the diagnosis associated with noninvasive peritoneal implants and the presence of numerous androgen receptors in the tumor cells. Although there is still insufficient data to validate a direct correlation between hormonotherapy and ovarian cancer in these patients, this case may reinforce previous reports on this association and highlights the relevance of radiological follow-up and bilateral salpingo-oophorectomy as part of gender reassignment surgery.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Itzel Araceli Ortiz Meza ◽  
Marco Antonio Ponce Camacho ◽  
Rodolfo Franco Márquez ◽  
Mauricio Delgado Morquecho ◽  
Raquel Garza Guajardo ◽  
...  

Tumors of the paratesticular region are generally tumors of slow growth, with little symptomatology and, in most cases, benign in nature; in this area, a borderline serous tumor may arise hypothetically from Müllerian metaplasia of the tunica vaginalis, which is histologically identical to its ovarian counterpart. We present a 10-year-old male, with right gynecomastia and ipsilateral hydrocele, showing an enlarged right testicle with a volume of 12 ml and a left testicle with a volume of 10 ml. A right orchiectomy was performed, which presented a poorly defined tan tumor of 1.8 cm that occupied the vaginal and epididymal tunica, and infiltrates the testicular parenchyma. Histological sections revealed a cystic neoplasm, with hierarchical papillary projections, covered by one or several epithelial columnar and hobnail cells with moderate atypia and scant mitosis. Immunohistochemical reactions were performed, resulting positive for PAX-8, epithelial membrane antigen, and CK7, confirming the diagnosis of borderline serous tumor. Since the first reported case in 1986, few have been reported, the majority of these in adults with only three cases in children. In the few cases reported, the prognosis is usually favorable after surgical resection, with disease-free follow-up for up to 18 years.


Medicine ◽  
2020 ◽  
Vol 99 (9) ◽  
pp. e19383
Author(s):  
Fengge Dong ◽  
Xiao Xie ◽  
Xue Wei ◽  
Miao-miao Jiao ◽  
Junwu Duan ◽  
...  

2017 ◽  
Vol 22 ◽  
pp. 9-12
Author(s):  
Madhuri Martin ◽  
Rachel N. Grisham ◽  
Gulisa Turashvili ◽  
Darragh F. Halpenny ◽  
Carol A. Aghajanian ◽  
...  

2021 ◽  
Vol 60 (2) ◽  
pp. 117-121
Author(s):  
Mizuho NAGAO ◽  
Hana MIFUNE ◽  
Junji TATSUSHIMA ◽  
Aiko IRIE ◽  
Yasushi HORIE ◽  
...  

2013 ◽  
Vol 57 (1) ◽  
pp. 96-99 ◽  
Author(s):  
Merih Tepeoglu ◽  
Özlem Özen ◽  
Ali Ayhan

2011 ◽  
Vol 29 (30) ◽  
pp. e763-e765 ◽  
Author(s):  
Donata Rohsbach ◽  
Fabian Trillsch ◽  
Marc Regier ◽  
Matthias Choschzick ◽  
Friedrich Kommoss ◽  
...  

2000 ◽  
Vol 124 (9) ◽  
pp. 1347-1348 ◽  
Author(s):  
Russell Vang ◽  
Jacki Abrams

Abstract A 79-year-old woman was evaluated for a ureteral stricture related to laser ablation of a tumor 6 months earlier at another institution. A ureteroscopic examination revealed an exophytic papillary tumor that was resected and examined histologically. The tumor was characterized by delicate papillae with thin stromal cores and numerous secondary micropapillae lined by small cuboidal to low columnar cells with uniform low-to-intermediate–grade nuclei, reminiscent of a serous borderline tumor of müllerian origin. The cell linings were 1 to 4 layers thick; mitotic figures were easily identified. The underlying stroma appeared edematous and contained scattered chronic inflammatory cells. No invasion was identified. After ascertaining that the patient had no known gynecologic neoplasm, the differential diagnoses considered included papillary nephrogenic adenoma, clear cell carcinoma, and the recently described entity of micropapillary transitional cell carcinoma. Because of the striking resemblance to serous carcinoma and the presence of significant mitotic activity, this case was felt to represent a case of micropapillary transitional cell carcinoma (World Health Organization grade 1 to 2) occurring in the ureter. To our knowledge, this tumor had some unique features (no areas of grade 3 nuclei or invasion) that have not been reported in tumors occurring in the urinary bladder. The transitional cell nature of the tumor cells was supported by the immunohistochemical staining pattern. The anatomic distribution of micropapillary transitional cell carcinoma is now expanded to include the ureter, and this tumor should be considered in the differential diagnosis for papillary lesions occurring in the ureter.


2018 ◽  
Vol 149 (suppl_1) ◽  
pp. S103-S103
Author(s):  
Sonia Veran-Taguibao ◽  
Roberto Alvaro Taguibao ◽  
Ted Farzaneh ◽  
Di Lu

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