scholarly journals Squamocolumnar Junction

2020 ◽  
Author(s):  
Keyword(s):  
Squamocolumnar Junction

Morphological characterization of the squamocolumnar junction of the esophagus in patients with and without Barrett's epithelium

1996 ◽  
Vol 41 (6) ◽  
pp. 1088-1098 ◽  
Author(s):  
Roger A. Sawhney ◽  
Helen M. Shields ◽  
Carol H. Allan ◽  
Jason A. Boch ◽  
Jerry S. Trier ◽  
...  
Keyword(s):  
Morphological Characterization ◽  
Squamocolumnar Junction ◽  
Barrett’S Epithelium ◽  
Barrett's Epithelium

A novel blueprint for ‘top down’ differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia

2013 ◽  
Vol 229 (3) ◽  
pp. 460-468 ◽  
Author(s):  
Michael Herfs ◽  
Sara O Vargas ◽  
Yusuke Yamamoto ◽  
Brooke E Howitt ◽  
Marisa R Nucci ◽  
...  
Keyword(s):  
Top Down ◽  
Squamocolumnar Junction ◽  
Reproductive Life

scholarly journals A Report of Two Cases of Age-Related Changes in Cervical Morphology in Postmenopausal Women with Vaginal Adenosis

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Marguerite B. Vigliani
Keyword(s):  
Middle Age ◽  
Morphological Changes ◽  
Pap Smears ◽  
Squamocolumnar Junction ◽  
Age Related ◽  
Normal Cervix ◽  
Vaginal Canal ◽  
Endocervical Canal ◽  
Over Time ◽  
Age Related Changes

This paper presents two cases of women who had extensive vaginal adenosis from prenatal DES exposure, extending almost halfway down the vaginal canal. Both women were followed for decades with annual exams and Pap smears until after menopause. Clinical examination in both cases initially showed an absent pars vaginalis of the cervix, vaginal adenosis, and shallowness of the fornices. Several decades of annual exams showed these stigmata of DES exposure gradually disappear as the upper vagina progressively contracted. After menopause the upper vagina in both cases transformed into what appeared to be a normal cervix with all adenosis involuted into a normal endocervical canal. A timeline was created to show the morphological changes that were observed over time. This timeline illustrates how severe vaginal stenosis above the level of the squamocolumnar junction developed in middle age and was followed in the postmenopause by fusion of the upper vaginal walls in the midline resulting in the appearance of a normal, but prolapsed, cervix.

scholarly journals Cervical Squamocolumnar Junction–specific Markers Define Distinct, Clinically Relevant Subsets of Low-grade Squamous Intraepithelial Lesions

2013 ◽  
Vol 37 (9) ◽  
pp. 1311-1318 ◽  
Author(s):  
Michael Herfs ◽  
Carlos Parra-Herran ◽  
Brooke E. Howitt ◽  
Anna R. Laury ◽  
Marisa R. Nucci ◽  
...  
Keyword(s):  
Low Grade ◽  
Squamous Intraepithelial Lesions ◽  
Squamocolumnar Junction ◽  
Intraepithelial Lesions

Histologic characterization of the squamocolumnar junction (SCJ) in children

1997 ◽  
Vol 45 (4) ◽  
pp. AB59 ◽  
Author(s):  
J Bornstein ◽  
D Winesett ◽  
E Rueda-Pedraza ◽  
V Rholl ◽  
C Sullivan ◽  
...  
Keyword(s):  
Squamocolumnar Junction

Reflux esophagitis or Helicobacter infection? – Diagnostic value of the inflammatory pattern in metaplastic mucosa at the squamocolumnar junction

2007 ◽  
Vol 203 (12) ◽  
pp. 831-837 ◽  
Author(s):  
Thomas Guenther ◽  
Andreas Hackelsberger ◽  
Doerthe Kuester ◽  
Peter Malfertheiner ◽  
Albert Roessner
Keyword(s):  
Reflux Esophagitis ◽  
Diagnostic Value ◽  
Squamocolumnar Junction ◽  
Inflammatory Pattern

scholarly journals Papsmear Examination for Diagnosing PreCancer Lesion in Invisible SquamoColumnar Junction

2017 ◽  
pp. 158-163
Author(s):  
Laila Nuranna ◽  
Sulaeman Daud ◽  
Gatot Purwoto ◽  
Hariyono Winarto ◽  
Kartiwa H Nuryanto
Keyword(s):  
Public Health ◽  
Visual Inspection ◽  
Descriptive Analysis ◽  
Age Distribution ◽  
Cross Sectional ◽  
Squamocolumnar Junction ◽  
Menopausal Women ◽  
Cross Sectional Design ◽  
Precancer Lesion ◽  
Cancer Lesion

Objective: To know the concealed pre-cancer lesion in women with invisible squamo-columnar junction (SCJ) by Papsmear examination. Method: This study was a descriptive cross-sectional design starting from August 2014 to March 2015 at several Public Health Cares in Jakarta. A total of 1,682 subjects were screened by Acetoacetate Visual Inspection (AVI) examination. After the data was collected, the process was continued by verification, editing, and coding. The descriptive analysis showed the percentage of SCJ in age distribution, the percentage of AVI examination based on SCJ, and the percentage of Papsmear examination in invisible SCJ according to negative AVI result. Result: There were 1,484 (88.2%) women with the visible SCJ and 198 (11.8%) women with invisible SCJ. The percentage of invisible SCJ in the menopausal women group was 122 (61,6%); meanwhile, in the non-menopausal women group, it was 76 (38.4%). Almost half of the percentage from visible SCJ was found in menopausal women group 45.8% (103/225 women). The positive AVI result was 4 (7.1%) in the menopausal women group and 52 (92.9%) in non-menopausal women group. The result of Papsmear examination with invisible SCJ were 197 (100%) normal. Conclusion: Almost half of visible SCJ was found in menopausal women group. Most of positive AVI result was found in the nonmenopausal women group. All women with the invisible SCJ have a normal Papsmear result. Keywords: acetoacetate visual inspection, papsmear, pre-cancer lesion, squamo-columnar junction

scholarly journals Can biopsies be omitted after normal colposcopy in women referred with low-grade cervical cytology? A prospective cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mette Mindedahl Jespersen ◽  
Berit Bargum Booth ◽  
Lone Kjeld Petersen
Keyword(s):  
Cervical Cancer ◽  
Cohort Study ◽  
Cancer Screening ◽  
Intraepithelial Neoplasia ◽  
Relative Increase ◽  
Low Grade ◽  
Squamocolumnar Junction ◽  
Study Participants ◽  
Cytology Screening

Abstract Background Controversy surrounds whether women with low-risk cytology screening results but a normal colposcopic assessment should have random biopsies taken. The aim of this study was to determine the yield of CIN2+ from one to four cervical biopsies in women with cytology of LSIL or ASCUS and a normal colposcopic impression. Methods Between January 2017 and September 2020, women over 18 years old referred for colposcopic examination due to either an abnormal smear (ASCUS+) or follow-up after previous cervical intraepithelial neoplasia (CIN) were invited to participate in the study. All study participants underwent colposcopic examination and had four biopsies taken. The biopsies were analyzed separately. Results In total, 1327 women with abnormal cervical cancer screening results or attending follow-up after a previous CIN diagnosis were enrolled in the study and examined by colposcopy. Of these, 173 were newly referred with cytology of LSIL or ASCUS and had a normal colposcopic impression and four adequate biopsies. Of these, 22.0% were diagnosed with CIN2+. When combining the results of the four biopsies, we found a 100% relative increase in CIN2+ cases compared to using only one biopsy (from 11.0% to 22.0%, P = 0.006). Conclusion As we found CIN2+ from random cervical biopsies in 22.0% of women with cytology of LSIL or ASCUS who had a normal colposcopic impression, we advocate performing four random cervical biopsies at the squamocolumnar junction in such women. Trial registration NCT04249856, January 31 2020 (retrospectively registered).

Impact of fundoplication on bolus transit across esophagogastric junction

1998 ◽  
Vol 275 (6) ◽  
pp. G1386-G1393 ◽  
Author(s):  
Peter J. Kahrilas ◽  
Shezhang Lin ◽  
Anita E. Spiess ◽  
James G. Brasseur ◽  
Raymond J. Joehl ◽  
...  
Keyword(s):  
Hiatal Hernia ◽  
Esophagogastric Junction ◽  
Nissen Fundoplication ◽  
Pressure Gradients ◽  
Axial Motion ◽  
Opening Pressure ◽  
Bolus Transit ◽  
Squamocolumnar Junction ◽  
Solid Bolus ◽  
Laparoscopic Nissen

This study analyzed the effect of fundoplication on the mechanics of liquid and solid bolus transit across the esophagogastric junction (EGJ). The squamocolumnar junction was endoscopically clipped in seven controls, seven hiatal hernia patients, and seven patients after laparoscopic Nissen fundoplication. Concurrent manometry and fluoroscopy were done during swallows of liquid barium and a 13-mm-diameter marshmallow. The EGJ opening, pressure gradients, transit efficacy, and axial motion were measured. The axial motion of the EGJ was reduced in the fundoplication and hiatal hernia patients. The opening dimensions at the squamocolumnar junction were similar among groups, but in each case the constriction limiting flow to the stomach was at the hiatus and this was substantially narrowed with fundoplication. As a result, liquid intrabolus pressure was increased and marshmallow transit frequently required multiple swallows. We conclude that fundoplication limits the axial mobility of the EGJ and leads to a restricted hiatal opening. These alterations decrease the efficacy of solid and liquid transit into the stomach and are potential causes of dysphagia in this population.

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