scholarly journals A Report of Two Cases of Age-Related Changes in Cervical Morphology in Postmenopausal Women with Vaginal Adenosis

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Marguerite B. Vigliani

This paper presents two cases of women who had extensive vaginal adenosis from prenatal DES exposure, extending almost halfway down the vaginal canal. Both women were followed for decades with annual exams and Pap smears until after menopause. Clinical examination in both cases initially showed an absent pars vaginalis of the cervix, vaginal adenosis, and shallowness of the fornices. Several decades of annual exams showed these stigmata of DES exposure gradually disappear as the upper vagina progressively contracted. After menopause the upper vagina in both cases transformed into what appeared to be a normal cervix with all adenosis involuted into a normal endocervical canal. A timeline was created to show the morphological changes that were observed over time. This timeline illustrates how severe vaginal stenosis above the level of the squamocolumnar junction developed in middle age and was followed in the postmenopause by fusion of the upper vaginal walls in the midline resulting in the appearance of a normal, but prolapsed, cervix.

2008 ◽  
Vol 32 (5) ◽  
pp. 381-389 ◽  
Author(s):  
Heike M. Buhl

This study investigates age-related changes and dyadic-specific differences in adult child–parent relationships. Using an individuation framework, two German samples of 224 and 105 participants aged between 21 and 47 years were administered the Network of Relationships Inventory, the Emotional Autonomy Scale and the Authority Reciprocity Questionnaire. Factor analyses resulted in a measurement model valid for adult children, their mothers and fathers. The model includes connectedness (with emotional and cognitive aspects) as well as individuality (assessed as power symmetry). Connectedness decreased with age. Symmetry in father–child relationships increased over time, while mother–child relationships were perceived to be symmetrical by early adulthood. Child–mother relationships were more connected than child–father relationships. Sons described themselves as more powerful than did daughters.


2020 ◽  
Author(s):  
Shuying Yu ◽  
Alexander Paul Boone ◽  
Carol He ◽  
Rie Davis ◽  
Mary Hegarty ◽  
...  

Accumulating evidence suggests that distinct aspects of successful navigation—path integration, acquiring spatial knowledge, and navigation strategies—change with advanced age. Yet, few studies have established whether navigation deficits emerge early in the aging process (prior to age 65) or whether early age-related deficits vary by sex. Here, we probed healthy young (ages 18-28) and midlife (ages 43-61) adults on three essential aspects of navigation. First, path integration ability shows negligible effects of sex or age. Second, robust sex differences in spatial knowledge acquisition are observed in young adulthood and persist, but are diminished, with age. Third, by midlife, men and women show decreased ability to acquire spatial knowledge and increased reliance on taking habitual paths. Together, our findings indicate that age-related changes in navigation ability and strategy are evident as early as midlife and that path integration ability is relatively spared in the transition from youth to middle age.


Author(s):  
Kendiss Olafson ◽  
Clare D. Ramsey ◽  
Marina Yogendran ◽  
Jason Waechter ◽  
Randy Fransoo ◽  
...  

Author(s):  
Антонина Владимировна Алексеева ◽  
Анатолий Яковлевич Рыжов ◽  
Данила Игоревич Игнатьев

Исследованы антропометрические показатели и параметры состава тела у лиц среднего возраста. Установлено, что некоторые калиперометрические показатели испытывают различие у мужчин и женщин. Калиперометрические показатели величины кожных покровов спины, медиальной и латеральной поверхностей бедер характеризуются тесными положительными корреляциями. Anthropometric indicators and parameters of body composition in middle-aged people were studied. It is established that some caliperometric indicators experience a difference in men and women. Caliperometric indicators of the size of the skin of the back, medial and lateral surfaces of the thighs are characterized by close positive correlations.


2020 ◽  
Vol 45 (1) ◽  
pp. 78-88
Author(s):  
Takeshi Nakagawa ◽  
Yukiko Nishita ◽  
Chikako Tange ◽  
Makiko Tomida ◽  
Kaori Kinoshita ◽  
...  

Prior evidence suggests that subjective well-being (SWB) remains relatively stable across adulthood. However, longitudinal evidence is sparse except in Western societies such as North America and Western Europe. We examined age-related changes in SWB (life satisfaction, positive affect, and negative affect) among middle-aged and older Japanese. We applied multilevel growth models to 14-year seven-wave longitudinal data of a dynamic cohort study. A total of 3,890 participants aged 40–81 at first assessment were included in the analysis. The longitudinal results demonstrated differential trajectories of SWB. Life satisfaction exhibited an accelerated increase in middle age but decreased and leveled off in old age. Positive affect increased in midlife and declined in late life. Negative affect remained stable in middle age but increased in old age. Demographics, health, and methodological correlates did not fully account for age-related changes in SWB. Of note, increases in negative affect in old age remained evident even after controlling for the correlates. In conclusion, life satisfaction was stable across adulthood, which was not the case with positive and negative affect. We discussed the possible mechanisms in these observed trajectories of SWB, in particular, negative affect in late life.


2015 ◽  
Vol 27 (4pt1) ◽  
pp. 1367-1383 ◽  
Author(s):  
Julia W. Felton ◽  
Michael J. Kofler ◽  
Cristina M. Lopez ◽  
Benjamin E. Saunders ◽  
Dean G. Kilpatrick

AbstractThis study tests competing models of the relation between depression and polysubstance use over the course of adolescence. Participants included a nationwide sample of adolescents (N = 3,604), ages 12 to 17 at study Wave 1, assessed annually for 3 years. Models were tested using cohort-sequential latent growth curve modeling to determine whether depressive symptoms at baseline predicted concurrent and age-related changes in drug use, whether drug use at baseline predicted concurrent and age-related changes in depressive symptoms, and whether initial levels of depression predicted changes in substance use significantly better than vice versa. The results suggest a transactional model such that early polysubstance use promotes early depressive symptoms, which in turn convey elevated risk for increasing polysubstance use over time, which in turn conveys additional risk for future depressive symptoms, even after accounting for gender, ethnicity, and household income. In contrast, early drug use did not portend risk for future depressive symptoms. These findings suggest a complicated pattern of interrelations over time and indicate that many current models of co-occurring polysubstance use and depressive symptoms may not fully account for these associations. Instead, the results suggest a developmental cascade, in which symptoms of one disorder promote symptoms of the other across intrapersonal domains.


2021 ◽  
pp. 174569162096407
Author(s):  
Melanie Killen ◽  
Audun Dahl

Moral reasoning is an essential part of how humans develop and a fundamental aspect of how human societies change over time. On a developmental timescale, reasoning about interpersonal disagreements and dilemmas spurs age-related changes in moral judgments from childhood to adulthood. When asked to distribute resources among others, even young children strive to balance competing concerns with equality, merit, and need. Over the course of development, reasoning and judgments about resource distribution and other moral issues become increasingly sophisticated. From childhood to adulthood, individuals not only evaluate acts as right or wrong but also take the extra steps to rectify inequalities, protest unfair norms, and resist stereotypic expectations about others. The development of moral reasoning also enables change on a societal timescale. Across centuries and communities, ordinary individuals have called for societal change based on moral concerns with welfare, rights, fairness, and justice. Individuals have effectively employed reasoning to identify and challenge injustices. In this article, we synthesize recent insights from developmental science about the roles of moral reasoning in developmental and societal change. In the concluding section, we turn to questions for future research on moral reasoning and change.


2015 ◽  
Vol 8 (1) ◽  
pp. 1-4
Author(s):  
Marianne Ledet Maagaard

Abstract Purpose: To examine whether age-related changes in refraction covary with changes in parameters describing accommodation and convergence over time in a group of Danish school children. Methods: Two-hundred and seventy-eight unselected Danish school children (7.1-13.9 years) without manifest strabismus were studied at baseline and after two years. Each examination included measurement of distance visual acuity, unilateral cover test, non-cycloplegic autorefraction, monocular amplitude of accommodation, monocular accommodation facility, near phoria, near point of convergence, and positive and negative fusional vergence. The changes in the measured parameters were studied over time, followed by the testing for dependencies in the development of these parameters. Results: After two years there was a significant increase in distance visual acuity (p=0.04), monocular accommodation facility (p<0.001), near point exophoria (p=0.04), near point of convergence (p=0.01), and fusional range (p<0.001), a significant reduction in hyperopia (p=0.01) and monocular amplitude of accommodation (p<0.001), while the midpoint of the fusional range changed significantly towards convergence (p<0.001). The increase in near point of convergence correlated significantly with the decrease in monocular amplitude of accommodation (p<0.001) and the convergent shift in the midpoint of the fusional range was significantly correlated with a larger fusional range (p<0.001). The changes in all other parameters were independent. Conclusions: The development of refraction, accommodation, and convergence parameters in school children over two years are independent. This may be due to separate processes regulating development, and suggests that therapeutic intervention may be performed on each of the parameters individually without a derived effect on the other parameters.


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