scholarly journals Drug Extravasation

2020 ◽  
Author(s):  
Keyword(s):  
Drug Extravasation

Docetaxel Recall Phenomenon at the Site of Previous Drug Extravasation

2010 ◽  
Vol 146 (10) ◽  
Author(s):  
Blanca Díaz Ley ◽  
Guillermo Guhl Millán ◽  
Javier Sanchez Perez ◽  
Javier Fraga ◽  
Amaro García Díez
Keyword(s):  
Drug Extravasation

scholarly journals Upper limb extravasation of cytotoxic drugs: results of the saline washout technique in children

2020 ◽  
Vol 14 (3) ◽  
pp. 230-235
Author(s):  
Virginie Mas ◽  
Anne Laure Simon ◽  
Ana Presedo ◽  
Cindy Mallet ◽  
Brice Ilharreborde ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Upper Limb ◽  
Skin Damage ◽  
Range Of Movement ◽  
Level Of Evidence ◽  
Early Referral ◽  
Soft Tissue Necrosis ◽  
Drug Extravasation ◽  
Specialized Department

Purpose Extravasation of cytotoxic vesicant drugs is a surgical emergency (within six hours) since this incident can lead to severe skin and soft-tissue damage. Outcomes after the saline washout procedure have been extensively described in adults, but rarely in children. The aim of this study was to evaluate the outcome of early saline washout procedure for upper limb cytotoxic drug extravasation in children. Methods All consecutive children with vesicant drug extravasation were retrospectively reviewed. The saline washout procedure was performed. Cosmetic aspect, residual pain and range of movement were analyzed as well as time to surgery and chemotherapy resumption at last follow-up. Results Between 2014 and 2018, 13 cytotoxic vesicant drug extravasations occurred (mean age 8 years (sem 5)), including 11 treated by the saline washout procedure. At mean follow-up of 11 months (sem 7), the patients had no or low pain and ranges of movement were fully conserved. Two patients (one within the six hours’ delay) had soft-tissue necrosis leading to extensive reconstructive surgery. Conclusion The saline washout procedure is safe and easy and significantly reduces the incidence of extensive skin damage. Early referral to a specialized department is essential. However, the key parameter remains prevention by educating medical staff and nurses about these injuries and by training them for early and urgent management. Level of Evidence IV

scholarly journals Drug extravasation along the route of a peritoneal catheter during intraperitoneal chemotherapy

Cancer ◽  
1987 ◽  
Vol 60 (8) ◽  
pp. 1731-1733 ◽  
Author(s):  
Ian G. Kerr ◽  
Carlo Deangelis ◽  
Dalal M. Assaad ◽  
Sherif S. Hanna
Keyword(s):  
Intraperitoneal Chemotherapy ◽  
Peritoneal Catheter ◽  
Drug Extravasation

The First Description of Docetaxel-Induced Recall Inflammatory Skin Reaction after Previous Drug Extravasation

2011 ◽  
Vol 45 (2) ◽  
pp. 277-277 ◽  
Author(s):  
Frauke Kramer ◽  
Cordula Schippert ◽  
Franziska Rinnau ◽  
Peter Hillemanns ◽  
Tjoung-Won Park-Simon
Keyword(s):  
Skin Reaction ◽  
Drug Extravasation ◽  
Inflammatory Skin

Use of silver sulphadiazine cream for burns caused by cytotoxic‐drug extravasation

1988 ◽  
Vol 148 (12) ◽  
pp. 657-657 ◽  
Author(s):  
P.J. Shaw ◽  
W.E. Nightingale ◽  
M.E. Bergin ◽  
M.M. Stevens
Keyword(s):  
Cytotoxic Drug ◽  
Drug Extravasation ◽  
Silver Sulphadiazine

Utility of Magnetic Resonance Imaging in the Surgical Management of Drug Extravasation: A Case Report

2017 ◽  
Vol 22 (01) ◽  
pp. 100-103 ◽  
Author(s):  
Yet Yen Yan ◽  
Tein Jin Tan
Keyword(s):  
Tissue Injury ◽  
Subcutaneous Tissue ◽  
Treatment Options ◽  
Soft Tissue Injury ◽  
Resonance Imaging ◽  
Tissue Necrosis ◽  
Mri Findings ◽  
Drug Extravasation ◽  
Operative Findings ◽  
Mri Study

We report a case of phenytoin extravasation complicated by eschar formation. Pre-operative MRI study showed a large non-enhancing area over the dorsum of the imaged right wrist and hand corresponding with the site of phenytoin extravasation and raising the suspicion of subcutaneous tissue necrosis. The MRI findings correlated well with the intra-operative findings. We believe that pre-operative MRI in drug extravasation cases can characterise the type of soft tissue injury and define the extent of injury. This helps the surgeon in the surgical approach and treatment options.

scholarly journals Drug extravasation: a dreaded complication

2009 ◽  
Vol 2009 (apr07 2) ◽  
pp. bcr0920080887-bcr0920080887 ◽  
Author(s):  
E. Una ◽  
F. Cuadrillero ◽  
F. Lopez-Lara
Keyword(s):  
Drug Extravasation
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