scholarly journals Major Axis Internal Diameter at End Ventricular Diastole

2020 ◽  
Author(s):  
Keyword(s):  
Major Axis ◽  
Internal Diameter

Detection and Characterization of earth-like Planets

1997 ◽  
Vol 161 ◽  
pp. 299-311 ◽  
Author(s):  
Jean Marie Mariotti ◽  
Alain Léger ◽  
Bertrand Mennesson ◽  
Marc Ollivier
Keyword(s):  
Direct Detection ◽  
Contrast Ratio ◽  
Angular Size ◽  
Physical Nature ◽  
Major Axis ◽  
Infrared Emission ◽  
Space Technology ◽  
Semi Major Axis ◽  
Earth Like Planets ◽  
Visible Wavelengths

AbstractIndirect methods of detection of exo-planets (by radial velocity, astrometry, occultations,...) have revealed recently the first cases of exo-planets, and will in the near future expand our knowledge of these systems. They will provide statistical informations on the dynamical parameters: semi-major axis, eccentricities, inclinations,... But the physical nature of these planets will remain mostly unknown. Only for the larger ones (exo-Jupiters), an estimate of the mass will be accessible. To characterize in more details Earth-like exo-planets, direct detection (i.e., direct observation of photons from the planet) is required. This is a much more challenging observational program. The exo-planets are extremely faint with respect to their star: the contrast ratio is about 10−10at visible wavelengths. Also the angular size of the apparent orbit is small, typically 0.1 second of arc. While the first point calls for observations in the infrared (where the contrast goes up to 10−7) and with a coronograph, the latter implies using an interferometer. Several space projects combining these techniques have been recently proposed. They aim at surveying a few hundreds of nearby single solar-like stars in search for Earth-like planets, and at performing a low resolution spectroscopic analysis of their infrared emission in order to reveal the presence in the atmosphere of the planet of CO H2O and O3. The latter is a good tracer of the presence of oxygen which could be, like on our Earth, released by biological activity. Although extremely ambitious, these projects could be realized using space technology either already available or in development for others missions. They could be built and launched during the first decades on the next century.

Platelet Accumulation on Fibrin-coated Polyethylene: Role of Platelet Activation and Factor XIII

1995 ◽  
Vol 73 (05) ◽  
pp. 850-856 ◽  
Author(s):  
F D Rubens ◽  
D W Perry ◽  
M W C Hatton ◽  
P D Bishop ◽  
M A Packham ◽  
...  
Keyword(s):  
Factor Xiii ◽  
Cross Linking ◽  
Internal Diameter ◽  
Static System ◽  
Graft Occlusion ◽  
Platelet Binding ◽  
Coated Surface ◽  
Platelet Accumulation ◽  
Polyethylene Tubing

SummaryPlatelet accumulation on small- and medium-calibre vascular grafts plays a significant role in graft occlusion. We examined platelet accumulation on the surface of fibrin-coated polyethylene tubing (internal diameter 0.17 cm) during 10 min of flow (l0ml/min) at high wall shear rate (764 s-1). Washed platelets labelled with 51Cr were resuspended in Tyrode solution containing albumin, apyrase and red blood cells (hematocrit 40%). When the thrombin that was used to form the fibrin-coated surface was inactivated with FPRCH2C1 before perfusion of the tubes with the platelet:red blood cell suspension, the accumulation of platelets was 59,840 ± 27,960 platelets per mm2, whereas accumulation on fibrin with residual active thrombin was 316,750 ± 32,560 platelets per mm2 (n = 4). When the fibrin on the surface was cross-linked by including recombinant factor XIII (rFXIII) in the fibrinogen solution used to prepare the fibrin-coated surface, platelet accumulation, after thrombin neutralization, was reduced by the cross-linking from 46,974 ± 9702 to 36,818 ± 7964 platelets per mm2 (n = 12, p <0.01). Platelet accumulation on tubes coated with D-dimer was ten times less than on tubes coated with D-domain; this finding also supports the observation that cross-linking of fibrin with the formation of γ-γ dimers reduces platelet accumulation on the fibrin-coated surface. Thrombin-activated platelets themselves were shown to cross-link fibrin when they had adhered to it during perfusion, or in a static system in which thrombin was used to form clots from FXIII-free fibrinogen in the presence of platelets. Thus, cross-linking of fibrin by FXIII in plasma or from platelets probably decreases the reactivity of the fibrin-containing thrombi to platelets by altering the lysine residue at or near the platelet-binding site of each of the γ-chains of the fibrinogen which was converted into the fibrin of these thrombi.

Analysis of nonsteroidal anti-inflammatory drugs by using microfluidic techniques: a review

2020 ◽  
Vol 16 ◽  
Author(s):  
Chiara Fanali ◽  
Giovanni D’Orazio ◽  
Alessandra Gentili ◽  
Salvatore Fanali
Keyword(s):  
Stationary Phases ◽  
Low Flow ◽  
High Mass ◽  
Internal Diameter ◽  
Uv Detectors ◽  
On Line ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Silica Phases ◽  
Liquid Chromatographic

: In this review paper, miniaturized techniques, including both electromigration and liquid chromatographic ones, have been considered discussing their main features in the analytical field for the separation and analysis of nonsteroidal anti-inflammatory drugs (NSAIDs). In capillary electrophoresis (CE) and nano-liquid chromatography (nano-LC), separation are performed in capillaries with internal diameter (I.D.) lower than 100 m and therefore flow rates in the range 100- 1000 nL/min are applied. Therefore due to the low flow rate, high mass sensitivity can be obtained. Usually conventional UV detectors are used on-line; however these techniques can be coupled with mass spectrometry (MS). CE and nano-LC have been also applied to the separation of NSAIDs using silica stationary phases (SP) modified with C18 promoting interaction with analytes mainly based on hydrophobic interaction. In addition the use of chiral SP resulted effective for the chiral resolution of these compounds. In addition to silica phases, monolithic (both organic and inorganic) material has also been used. Although most of the presented studies aimed to demonstrate the usefulness of the considered microfluidic techniques, some applications to real samples have also been reported.

scholarly journals Ionized gas kinematics of massive elliptical galaxies in CALIFA and in cosmological zoom-in simulations

2020 ◽  
Vol 635 ◽  
pp. A41
Author(s):  
Jan Florian ◽  
Bodo Ziegler ◽  
Michaela Hirschmann ◽  
Polychronis Papaderos ◽  
Ena Choi ◽  
...  
Keyword(s):  
Radial Profile ◽  
Major Axis ◽  
Velocity Fields ◽  
Host Galaxies ◽  
Ionized Gas ◽  
Massive Galaxies ◽  
Gas Kinematics ◽  
Major Merger ◽  
Ordered Motion ◽  
Integral Field

Context. Powerful active galactic nuclei (AGN) are supposed to play a key regulatory role on the evolution of their host galaxies by shaping the thermodynamic properties of their gas component. However, little is known as to the nature and the visibility timescale of the kinematical imprints of AGN-driven feedback. Gaining theoretical and observational insights into this subject is indispensable for a thorough understanding of the AGN-galaxy coevolution and could yield empirical diagnostics for the identification of galaxies that have experienced a major AGN episode in the past. Aims. We present an investigation of kinematical imprints of AGN feedback on the warm ionized gas medium (WIM) of massive early-type galaxies (ETGs). To this end, we take a two-fold approach that involves a comparative analysis of Hα velocity fields in 123 local ETGs from the CALIFA (Calar Alto Legacy Integral Field Area Survey) integral field spectroscopy survey with 20 simulated galaxies from high-resolution hydrodynamic cosmological SPHgal simulations. The latter were resimulated for two modeling setups, one with and another without AGN feedback. Methods. In order to quantify the effects of AGN feedback on gas kinematics, we measured three parameters that probe deviations from simple regular rotation by using the kinemetry package. These indicators trace the possible presence of distinct kinematic components in Fourier space (k3, 5/k1), variations in the radial profile of the kinematic major axis (σPA), and offsets between the stellar and gas velocity fields (Δϕ). These quantities were monitored in the simulations from a redshift 3 to 0.2 to assess the connection between black hole accretion history, stellar mass growth, and the kinematical perturbation of the WIM. Results. Observed local massive galaxies show a broad range of irregularities, indicating disturbed warm gas motions, which is irrespective of being classified via diagnostic lines as AGN or not. Simulations of massive galaxies with AGN feedback generally exhibit higher irregularity parameters than without AGN feedback, which is more consistent with observations. Besides AGN feedback, other processes like major merger events or infalling gas clouds can lead to elevated irregularity parameters, but they are typically of shorter duration. More specifically, k3, 5/k1 is most sensitive to AGN feedback, whereas Δϕ is most strongly affected by gas infall. Conclusions. We conclude that even if the general disturbance of the WIM velocity is not a unique indicator for AGN feedback, irregularity parameters that are high enough to be consistent with observations can only be reproduced in simulations with AGN feedback. Specifically, an elevated value for the deviation from simple ordered motion is a strong sign for previous events of AGN activity and feedback.

scholarly journals Differential Sorting of Microparticles Using Spiral Microchannels with Elliptic Configurations

Micromachines ◽  
2020 ◽  
Vol 11 (4) ◽  
pp. 412
Author(s):  
Kaan Erdem ◽  
Vahid Ebrahimpour Ahmadi ◽  
Ali Kosar ◽  
Lütfullah Kuddusi
Keyword(s):  
Cell Sorting ◽  
Microfluidic Channel ◽  
Major Axis ◽  
Label Free ◽  
Flow Rates ◽  
Inertial Focusing ◽  
Size Dependent ◽  
Curved Channels ◽  
Aspect Ratios ◽  
Dependent Cell

Label-free, size-dependent cell-sorting applications based on inertial focusing phenomena have attracted much interest during the last decade. The separation capability heavily depends on the precision of microparticle focusing. In this study, five-loop spiral microchannels with a height of 90 µm and a width of 500 µm are introduced. Unlike their original spiral counterparts, these channels have elliptic configurations of varying initial aspect ratios, namely major axis to minor axis ratios of 3:2, 11:9, 9:11, and 2:3. Accordingly, the curvature of these configurations increases in a curvilinear manner through the channel. The effects of the alternating curvature and channel Reynolds number on the focusing of fluorescent microparticles with sizes of 10 and 20 µm in the prepared suspensions were investigated. At volumetric flow rates between 0.5 and 3.5 mL/min (allowing separation), each channel was tested to collect samples at the designated outlets. Then, these samples were analyzed by counting the particles. These curved channels were capable of separating 20 and 10 µm particles with total yields up to approximately 95% and 90%, respectively. The results exhibited that the level of enrichment and the focusing behavior of the proposed configurations are promising compared to the existing microfluidic channel configurations.

Estimation of response slopes in respiratory control

1984 ◽  
Vol 56 (2) ◽  
pp. 536-539 ◽  
Author(s):  
D. L. Sherrill ◽  
G. D. Swanson
Keyword(s):  
Statistical Approach ◽  
Ventilatory Response ◽  
Respiratory Control ◽  
Major Axis ◽  
Bivariate Normal Distribution ◽  
Directional Statistics ◽  
Control Behavior ◽  
Slope Estimate ◽  
Partial Pressure Of Co2 ◽  
Reduced Major Axis

The ventilatory response to changes in alveolar (arterial) CO2 is widely used as an index of respiratory control behavior. Methods for estimating these response slopes should incorporate the possibility that there may be errors in both the independent (partial pressure of CO2) and dependent (ventilation) variables. In a recent paper Daubenspeck and Ogden (J. Appl. Physiol. Respirat. Environ. Exercise Physiol. 45:823–829, 1978) have suggested problems inherent in the traditional technique of reduced major axis and have suggested a more contemporary technique of directional statistics. We have previously analyzed both techniques and developed a method to overcome the problems of reduced major axis and problems inherent in the use of directional statistics. Under the assumption of a bivariate normal distribution, we demonstrate that our slope estimate is similar to the maximum likelihood estimate proposed by Mardia et al. (J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 54: 309–313, 1983) for this problem. In addition, we demonstrate a bootstrap statistical approach when the distributions are not normally distributed. These concepts are illustrated using O2-CO2 interaction data.

scholarly journals I. Thermo-electric behaviour of aqueous solutions with mercurial electrodes

1879 ◽  
Vol 29 (196-199) ◽  
pp. 472-482 ◽  
Keyword(s):  
Aqueous Solution ◽  
Aqueous Solutions ◽  
Internal Diameter ◽  
Thermo Electric ◽  
Thin Glass ◽  
Mercury Surface

In order to investigate this subject, I devised and constructed the following apparatus :—A and B are two thin glass basins, 81 millims. internal diameter (= 5,153 sq. millims. of mercury surface), and 6·0 centims. deep; each containing a layer of mercury about 1·0 centim. deep, covered by a layer, about 3 centims. deep, of the aqueous solution to be examined.

Sign in / Sign up

Export Citation Format

Share Document