Vaginal Intraepithelial Neoplasia

2020 ◽  
Author(s):  
Keyword(s):  
Intraepithelial Neoplasia ◽  
Vaginal Intraepithelial Neoplasia

Vaginal intraepithelial neoplasia: clinical-therapeutic analysis of 33 cases

2005 ◽  
Vol 272 (4) ◽  
pp. 261-264 ◽  
Author(s):  
Eddie F. C. Murta ◽  
Milton A. Neves Junior ◽  
Luciano R. F. Sempionato ◽  
Marcos C. Costa ◽  
Paulo J. Maluf
Keyword(s):  
Intraepithelial Neoplasia ◽  
Vaginal Intraepithelial Neoplasia

Rare forms of vaginal diseases in women after panhysterectomy

2020 ◽  
Vol 19 (5) ◽  
pp. 150-155
Author(s):  
N.V. Zarochentseva ◽  
◽  
V.I. Krasnopolskiy ◽  
О.А. Misyukevich ◽  
I.V. Barinova ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Precancerous Lesions ◽  
Cell Cancer ◽  
Intraepithelial Neoplasia ◽  
Vaginal Wall ◽  
Cytological Examination ◽  
Clinical Observations ◽  
Papillomavirus Infection ◽  
Vaginal Intraepithelial Neoplasia ◽  
History Of

The article presents clinical observations of the development of precancerous conditions of the vaginal vault, and also squamous cell cancer in women after panhysterectomy. The examination included: comprehensive vaginoscopy, cytological examination of vaginal wall smears, human papillomavirus test, histological examination of bioplates. Conclusion. Panhysterectomy does not guarantee the absence of precancerous lesions of the vagina or vaginal cancer. Therefore, routine screening (cytology, testing for high-risk human papillomavirus, vaginoscopy) should be continued in women after panhysterectomy with a history of cervical intraepithelial neoplasias for at least 20 years, even in women older than 65 years. Key words: vaginal intraepithelial neoplasia, human papillomavirus, panhysterectomy, papillomavirus infection, cervical cancer, photodynamic therapy

Role of CO2 laser Vaporization in the Management of Vaginal Intraepithelial Neoplasia

1997 ◽  
Vol 8 (2) ◽  
pp. 124
Author(s):  
Dae Yeon Kim ◽  
Yong Beom Kim ◽  
Su Yeon Kim ◽  
Jae Weon Kim ◽  
Hoh Hyun Park ◽  
...  
Keyword(s):  
Co2 Laser ◽  
Intraepithelial Neoplasia ◽  
Laser Vaporization ◽  
Vaginal Intraepithelial Neoplasia

scholarly journals In vivo optical cellular diagnosis for uterine cervical or vaginal intraepithelial neoplasia using flexible gastrointestinal endocytoscopy -a prospective pilot study-

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Shoko Ono ◽  
Ayako Nozaki ◽  
Kana Matsuda ◽  
Emi Takakuwa ◽  
Naoya Sakamoto ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Predictive Value ◽  
Intraepithelial Neoplasia ◽  
Observer Agreement ◽  
Optical Biopsy ◽  
Link Type ◽  
Guided Biopsy ◽  
Vaginal Intraepithelial Neoplasia ◽  
High Level

Abstract Backgrouund For patients with any kind of atypical squamous intraepithelial lesion of the uterine cervix or vagina, colposcopy and punch biopsy are common procedures for histological determination following cytology. However, colposcopy-guided biopsy does not provide a high level of diagnostic accuracy. The aim of this study was to determine the usefulness of optical biopsy in vivo using endocytoscopy compared with conventional procedures using colposcopy. Methods Between May 2018 and March 2019, patients who were scheduled for cervical conization or mapping biopsies of the vagina were prospectively enrolled. Endocytoscopy was performed by senior endoscopists prior to scheduled procedures, and endocytoscopic images and biopsy samples were taken from the most prominent site and surrounding area of the cervical or vaginal lesions. The collection process of images was randomized and anonymous, and three doctors separately evaluated the images according to the ECA classification. ECA 4 and 5 are indicative of endoscopic malignancy. The primary endpoint was diagnostic accuracy (benign or malignant: cervical intraepithelial neoplasia (CIN) 3 or vaginal intraepithelial neoplasia (VAIN) 3 or worse) of cell images at the most prominent site in each patient. Results A total of 28 consecutive patients were enrolled. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of endocytoscopic images were 95.0% (84.8–98.6%), 87.5% (61.9–96.5%), 95.0% (84.8–98.6%), 87.5% (61.9–96.5%) and 92.9% (78.2–98.0%), respectively. Inter-observer agreement among three reviewers was 0.78 (0.08–9.88, P < 0.01). On the other hand, the accuracy of colposcopy-guided biopsy was 74.1% (64.0–84.0%). Conclusions Optical cell diagnosis of cervical or vaginal intraepithelial neoplasia using endocytoscopy provides a high level of diagnostic accuracy. Trial registration The study was registered with the UMIN database (ID: 000031712). UMIN000031712. Registered 16 March 2017,

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