scholarly journals Bone and Connective Tissue Pathology

2020 ◽  
Author(s):  
Author(s):  
Aziz Shaibani

Deformities are important markers for congenital and hereditary neuromuscular disorders. Kyphosis, scoliosis, Pes Cavus, for example, are common in CMT and hereditary ataxias. Deformities may also result from long-term weakness and asymmetry. Chronic neuropathies with distal weakness may lead to gradual changes in the height of feet arches. A high foot arche that is corrected with wight bearing or manually, is usually not congenital. Other types of deformities are related to connective tissue pathology, which can be associated with neuromuscular disorders, for example multiple lipomatosis, scleroderma, contractures, nephrogenic systemic sclerosis, and so on. This chapter shows examples of these deformities. Musculoskeletal deformities may lead to entrapment neuropathies.


2020 ◽  
Vol 18 (5) ◽  
pp. 140-142
Author(s):  
L. B. NOVIKOVA ◽  
◽  
A. P. AKOPYAN ◽  
K. M. SHARAPOVA ◽  
R. F. LATYPOVA ◽  
...  

The article presents a description of a clinical case of ischemic stroke in a 32 year old patient as a consequence of dissection of the vertebral artery against the background of congenital connective tissue pathology, provoked by a sports load.


2021 ◽  
Vol 25 (2(98)) ◽  
pp. 114-118
Author(s):  
O. Usenko ◽  
Ya. Voitiv ◽  
S. Shcherbyna

Objective – to develop a method for diagnosing undifferentiated connective tissue dysplasia (UCTD) in patients with surgical pathology.Material and methods. The object of the study comprises 96 patients with surgical pathology who were treated in the department of thoracoabdominal surgery of the Shalimov National Institute of Surgery and Transplantology during 2017-2020 and 20 practically healthy people (comparison group). Laboratory, instrumental, histological, immunohistochemical studies and statistical analysis were performed.Results. The developed method contains an assessment of the most informative phenotypic and visceral signs of connective tissue pathology. The main attention is paid to the features that characterize the visceral manifestations of UDCT, especially functional and morphological changes of the digestive organs, which is extremely important in abdominal surgery. Ultrasonography is used to analyze the width of the white line of the abdomen and the condition of the abdominal and retroperitoneal organs, determining the presence of diastase of the rectus abdominis and splanchnoptosis. Studies of the effectiveness of the proposed method have shown that it can be used to diagnose UDCT in patients with surgical pathology, which is necessary to select effective treatment tactics and prevent complications in such patients.Conclusions. A method for diagnosing undifferentiated connective tissue dysplasia has been developed, which evaluates the most informative phenotypic signs of connective tissue pathology and considers the peculiarities of pathology in patients of a surgical hospital.


2018 ◽  
Vol 35 (5) ◽  
pp. 36-41
Author(s):  
A. S. Denisov ◽  
D. P. Zagorak

Aim. To detect the most informative signs of connective tissue dysplasia (CTD) and develop the method for CTD express diagnosis in conditions of ambulatory and stationary traumatologo-orthopedic service. Materials and methods. Sixty practically healthy persons were examined. To diagnose the connective tissue pathology, there were used the criteria developed by S.K. Evtushenko (2002), T.Yu. Smolnova (2003) and T.I. Kartunova (2006). Eighteen the most informative criteria were chosen. Results. The paper is devoted to a widespread and yet not fully studied problem – the connective tissue dysplasia. The basic signs of this disease were analyzed. The most informative criteria of connective tissue dysplasia were singled out. Express test for primary diagnosis of this pathology in conditions of traumatologo-orthopedic service was offered. Conclusions. Express test of the state of connective tissue structure is simple to perform. It can be used to improve surgical aids in connective tissue dysplasia, when additional stabilization of loco motor system is required.


2021 ◽  
Vol 19 (4) ◽  
Author(s):  
Ya.Yu Voitiv ◽  
O.O. Dyadyk

Objective – to improve the treatment results of patients with eventration by determiningthe role of undifferentiated connective tissue dysplasia in the development of thiscomplication.Material and methods. The object of the study comprises 33 patients with eventrationwho were treated in the department of thoracoabdominal surgery of Shalimov NationalInstitute of Surgery and Transplantology during 2017-2020.Results. At complex pathomorphological research of aponeurosis fragments similarmorphological changes have been revealed in groups of patients with phenotypic signsof undifferentiated connective tissue dysplasia and eventration. Immunohistochemicalexamination of tissues with monoclonal antibodies to α-SMA revealed uneven, focalexpression in smooth muscle differentiation cells and fibroblasts in both groups. In thestudies with monoclonal antibodies to Collagen IV, moderate positive expression in thebasement membrane of the blood vessels, in smooth muscle cells of the muscular layerof the vascular wall, in areas of the connective tissue was observed, that is a sign ofpathological remodeling of the connective tissue.Conclusions. Similar pathomorphological changes of the aponeurosis in groups withphenotypic signs of undifferentiated connective tissue dysplasia and post-operativeeventration confirm the role of the connective tissue pathology in the development of thiscomplication.


2019 ◽  
Vol 405 ◽  
pp. 77
Author(s):  
D. Khaibullina ◽  
Y. Maximov ◽  
F. Devlikamova ◽  
A. Khaibullina ◽  
D. Mansurov

Therapy ◽  
2020 ◽  
Vol 6_2020 ◽  
pp. 35-39
Author(s):  
Yalaev B.I. Yalaev ◽  
Tyurin A.V. Tyurin ◽  
Nurlygayanov R.Z. Nurlygayanov ◽  
Khusainova R.I. Khusainova ◽  
◽  
...  

Sign in / Sign up

Export Citation Format

Share Document