Role of color-coded virtual touch tissue imaging in suspected thyroid nodules

2021 ◽  
pp. 1-10
Author(s):  
Kai-Mei Lian ◽  
Teng Lin
Keyword(s):  
Regression Model ◽  
Thyroid Nodules ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Tissue Imaging ◽  
Multivariate Logistic Regression Model ◽  
The Us ◽  
The Difference ◽  
Virtual Touch Tissue Imaging

BACKGROUND: Conventional ultrasound (US) is the most widely used imaging test for thyroid nodule surveillance. OBJECTIVE: We used the color-coded virtual touch tissue imaging (VTI) in the Acoustic Radiation Force Impulse (ARFI) technique to assess the hardness of the American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TI-RADS) TR3-5 nodules. The ability of color-coded VTI (CV) to discriminate between benign and malignant nodules was investigated. METHODS: In this retrospective study, US and CV were performed on 211 TR3-5 thyroid lesions in 181 consecutive patients. All nodules were operated on to obtain pathological results. A multivariate logistic regression model was chosen to integrate the data obtained from the US and CV. RESULTS: The area under the receiver operating characteristic (ROC) curve for the model was 0.945 (95% CI, 0.914 to 0.976). The cutoff value of predictive probability for diagnosing malignant thyroid nodules was 10.64%, the sensitivity was 94.43%, and the specificity was 83.12%. Through comparing with US and CV, respectively, it had been observed that the regression model had the best performance (all P< 0.001). However, when the US was compared with CV, the difference was not significant (P= 0.3304). CONCLUSIONS: A combination of US and CV should be recommended for suspected malignant thyroid nodules in clinical practice.

Virtual Touch Tissue Imaging on Acoustic Radiation Force Impulse Elastography

2014 ◽  
Vol 33 (4) ◽  
pp. 585-595 ◽  
Author(s):  
Yi-Feng Zhang ◽  
Yong He ◽  
Hui-Xiong Xu ◽  
Xiao-Hong Xu ◽  
Chang Liu ◽  
...  
Keyword(s):  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Tissue Imaging ◽  
Virtual Touch Tissue Imaging

scholarly journals Successful experience in the use of ultrasound elastography in the differentiating of lymphomatous and metastatic superficial lymphadenopathy

2020 ◽  
Vol 15 (2) ◽  
pp. 42-48
Author(s):  
E. V. Kovaleva ◽  
T. Yu. Danzanova ◽  
G. T. Sinyukova ◽  
E. A. Gudilina ◽  
P. I. Lepedatu ◽  
...  
Keyword(s):  
Shear Wave ◽  
Wave Velocity ◽  
Shear Wave Velocity ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Area Ratio ◽  
Ultrasound Elastography ◽  
Acoustic Radiation Force Impulse ◽  
Tissue Imaging ◽  
Hodgkin's Lymphomas

The objective: to evaluate the possibilities of ARFI technology (Acoustic Radiation Force Impulse), including Virtual Touch™ Tissue Imaging (VTI) and Virtual Touch™ Tissue Quantification (VTQ) for differentiation of lymphomatous and metastatic superficial lymphadenopathy.Materials and methods. The prospective study included 138 patients with enlarged superficial lymph nodes (LN). Based on a previous histological examination, patients were divided into two groups: 1st group (n = 108) – patients with non-Hodgkin’s lymphomas and Hodgkin’s lymphoma; 2nd group (n = 30) – patients with metastasis of solid tumors in superficial LN. All patients underwent ultrasound elastography of the enlarged LN using ARFI technology. In VTI study the Area Ratio parameter was evaluated, and the minimum and average values of the shear wave velocity were estimated in VTQ study.Results. According to the results of VTI study the Area Ratio parameter for enlarged LN in lymphoma (1st group) and for metastatic lymphadenopathy (2 nd group) were 1.031 ± 0.197 and 0.851 ± 0.15, respectively (p = 0.000009). The cut off value of the Area Ratio parameter was 0.901 with sensitivity, specificity and accuracy 80.6, 70.0 and 78.8 %, respectively. Minimum values of shear wave velocities for 1st and 2 nd groups were 1.980 ± 0.557 and 2.214 ± 0.367 m/s, respectively (p = 0.032). The cut off values of the average shear wave velocity in the differentiating of lymphomatous and metastatic lymphadenopathy are determined at the level of 2.00 m/s, with sensitivity of 70.0 %, specificity of 59.3 %, and accuracy of 61.6 %.Conclusion. Ultrasound elastography with ARFI technology demonstrated statistically significant differences in the Area Ratio parameter and in the minimum shear wave velocity in the enlarged superficial LN in lymphoma and with metastasis that can be used as a preliminary non-invasive differential diagnosis of enlarged superficial LN in these conditions. Moreover, the Area Ratio parameter has a statistically more significant effect on differentiating of lymphomatous and metastatic lymphadenopathy.

Acoustic Radiation Force Impulse (ARFI) imaging for the distinction between benign and malignant thyroid nodules

2015 ◽  
Vol 120 (6) ◽  
pp. 579-583 ◽  
Author(s):  
Cihad Hamidi ◽  
Cemil Göya ◽  
Salih Hattapoğlu ◽  
Ömer Uslukaya ◽  
Memik Teke ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Arfi Imaging

ARFI ELASTOGRAPHY IN THE DIAGNOSIS OF THYROID NODULES

2018 ◽  
Vol 8 (5) ◽  
pp. 85-90
Author(s):  
Hanh Dau Thi My ◽  
Quan Nguyen Phuoc Bao ◽  
Thao Nguyen Thanh
Keyword(s):  
Strain Distribution ◽  
Thyroid Nodules ◽  
Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Tissue Imaging ◽  
Tissue Elasticity ◽  
Arfi Elastography ◽  
2D Ultrasound ◽  
The Mean ◽  
Benign Nodules

Objective: To describe the sonography characteritics of the thyroid nodules using Acoutic Radiation Force Impulse Imaging (ARFI), and to evaluate the role of ARFI technique combination with 2D Ultrasound in diagnosing thyroid nodules. Methods: 2D Ultrasound and ARFI Elatography were caried out in 63 patients who have thyroid nodules. Images of 2D Ultrasound were classified according to Russ G. (French TIRADS). ARFI Elastography was performed by 2 techniques: “ Virtual Touch tissue imaging” in order to image of strain distribution and “Virtual Touch tissue quantification Imaging” to measure the shear wave velocity (SWV) in the tissue. Strain distribution was classified according to Xu’s VTI grading method. SWV was measured in the solid portions or suspicious regions of a nodule, avoiding cystic portions or calcifications. According to the results of pathology, we determine and compare the value between 2D Ultrasound plus ARFI elastography and 2D Ultrasound alone. Results: 63 patients with thyroid nodules: 14 malignant nodules and 49 benign nodules. The mean SWV of benign nodules were 1.78±1.22 m/s, the mean SWV of malignant nodules were 7.09±2.87 m/s. The best cut-off point for SWV was 2.4 m/s. For VTI, grade IV was the best cut-off value in differentiation of benign and malignant thyroid nodules. 2D Ultrasound plus VTI and 2D Ultrasound plus VTQ: Se 100% and 100%, Sp 87.8% and 85.7%, PPV 70% and 66.7%, NPV 100% and 100%, Acc 90.5 % and 88.9% (K=0.761 and K=0.727). Conclusions: In addition to the morphologic characteristics of thyroid nodules, ARFI provides information about lesion’s tissue elasticity, which can be useful tool in diferential diagnosis of thyroid nodules. Key words: Acoustic Radiation Force Impulse Imaging (ARFI), thyroid nodules

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