Multi-layer neural network analysis of cerebrospinal fluid pressure patterns in idiopathic normal-pressure hydrocephalus

1996 ◽  
Vol 4 (4) ◽  
pp. 393-401 ◽  
Author(s):  
P. Mazzone ◽  
L. Fortuna ◽  
P. Arena ◽  
R. Pisani
Keyword(s):  
Neural Network ◽  
Cerebrospinal Fluid ◽  
Network Analysis ◽  
Normal Pressure Hydrocephalus ◽  
Fluid Pressure ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
Cerebrospinal Fluid Pressure ◽  
Neural Network Analysis

Normal pressure hydrocephalus. Influences on cerebral hemodynamic and cerebrospinal fluid pressure-chemical autoregulation

1984 ◽  
Vol 21 (2) ◽  
pp. 195-203 ◽  
Author(s):  
John S. Meyer ◽  
Hisao Tachibana ◽  
Jeffrey P. Hardenberg ◽  
Richard E. Dowell ◽  
Yasuhisa Kitagawa ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Normal Pressure Hydrocephalus ◽  
Fluid Pressure ◽  
Normal Pressure ◽  
Cerebrospinal Fluid Pressure ◽  
Cerebral Hemodynamic ◽  
Pressure Chemical

scholarly journals Quantitative Analysis of Cerebrospinal Fluid Pressure Gradients in Healthy Volunteers and Patients with Normal Pressure Hydrocephalus

2015 ◽  
Vol 55 (8) ◽  
pp. 657-662 ◽  
Author(s):  
Naokazu HAYASHI ◽  
Mitsunori MATSUMAE ◽  
Satoshi YATSUSHIRO ◽  
Akihiro HIRAYAMA ◽  
Afnizanfaizal ABDULLAH ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Quantitative Analysis ◽  
Healthy Volunteers ◽  
Normal Pressure Hydrocephalus ◽  
Fluid Pressure ◽  
Normal Pressure ◽  
Cerebrospinal Fluid Pressure ◽  
Pressure Gradients

scholarly journals Evaluating the cerebrospinal fluid tap test with the Hellström iNPH scale for patients with idiopathic normal pressure hydrocephalus

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Johanna Rydja ◽  
Andreas Eleftheriou ◽  
Fredrik Lundin
Keyword(s):  
Cerebrospinal Fluid ◽  
Scale Score ◽  
Normal Pressure Hydrocephalus ◽  
Postoperative Outcome ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
Urinary Continence ◽  
Predictive Values ◽  
Tap Test ◽  
Total Scale Score

Abstract Background The cerebrospinal fluid tap test (CSF TT) is used for selecting shunt surgery candidates among patients with idiopathic normal pressure hydrocephalus (iNPH). We aimed to evaluate the predictive value of the CSF TT, by using the Hellström iNPH scale for shunted iNPH patients with a standardized method. Methods One hundred and sixteen shunt-operated iNPH patients were retrospectively included in this study. The gait and balance domains in the iNPH scale were used as outcome measures for the CSF TT and the total iNPH scale score as the postoperative outcome. A positive response to CSF TT was defined as a change of ≥ 5 points in the gait domain and ≥ 16 points in the balance domain. Differences between CSF TT responders and non-responders, sensitivity, specificity, positive and negative predictive values, accuracy, and correlations between changes from baseline to post CSF TT and from baseline to the postoperative follow-up, were calculated. Results In the CSF TT there were 63.8% responders in the gait domain and correspondingly 44.3% in the balance domain. CSF TT responders had a significantly better postoperative outcome in the total scale score (gait P ≤ 0.001, balance P ≤ 0.012) and gait CSF TT responders improved more in gait (P ≤ 0.001) and balance CSF TT responders in balance (P ≤ 0.001). No differences between CSF TT gait or balance responders could be found in neuropsychological or urinary continence assessments postoperatively. The sensitivity and specificity of the CSF TT and the outcome of the total iNPH scale score postoperatively were 68.1% and 52.0% for gait and 47.8% and 68.0% for balance, respectively. Conclusions The CSF TT, with the Hellström iNPH scale as the outcome measure, has clear limitations in predicting postoperative results. The gait domain may be used to predict outcomes for gait, but the balance domain is too insensitive.

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