Selective head cooling and acute kidney injury in neonates with hypoxic ischemic encephalopathy

2020 ◽  
Vol 13 (1) ◽  
pp. 21-30
Author(s):  
I. Nour ◽  
R. Elmaghraby ◽  
R. Shehata ◽  
A. El-Refaey ◽  
H. Aldomiaty ◽  
...  
2019 ◽  
Vol 35 (3) ◽  
pp. 477-483 ◽  
Author(s):  
Francesco Cavallin ◽  
Giulia Rubin ◽  
Enrico Vidal ◽  
Elisa Cainelli ◽  
Luca Bonadies ◽  
...  

2016 ◽  
Vol 03 (03) ◽  
pp. 254-257
Author(s):  
Sumit Agrawal ◽  
Partha Kumar Chaudhuri ◽  
Anil Kumar Chaudhary ◽  
Deepak Kumar

2020 ◽  
Vol 7 (11) ◽  
pp. 2205
Author(s):  
Rita Chaudhary ◽  
Anil Kumar Tiwari ◽  
Farhan Usmani

Background: Perinatal asphyxia causes multi organ dysfunction resulting in renal (50%) and neurological (28%) compromise with 1.4% of hypoxic ischemic encephalopathy (HIE) and almost 20% death in India. Early recognition of acute kidney injury (AKI) is important in babies with HIE to facilitate appropriate fluid and electrolyte management for a stable biochemical milieu is vital.Methods: A prospective case control study was done in Patna Medical College and Hospital, Patna between January 2019 and March 2020. 70 term asphyxiated neonates with HIE as cases and 70 healthy neonates as control were taken. AKI on basis of p RIFLE criteria and HIE on the basis of 5 minute APGAR score were determined and correlated.Results: 58.6%cases of AKI with 73% pre renal and 61% non-oliguric type were found in asphyxiated neonates with HIE blood urea and serum creatinine values were significantly higher in asphyxiated babies than control group babies (p<0.0001).Conclusions: The extent of AKI is directly proportional to severity of HIE. 


2021 ◽  
Vol 11 (1(39)) ◽  
pp. 48-57
Author(s):  
Liliia Stryzhak ◽  
І. Anikin ◽  
Y. Samara

Objective: to analyze the scientific literature sources inorder to study and systematize data on modern aspects ofdiagnosis and treatment of acute kidney injury in full-termnewborns with hypoxic-ischemic encephalopathy.Perinatal asphyxia is a multisystem disorder resultingfrom redistribution of blood flow, with renal dysfunctionbeing one of the most common complications and reaching50% of other multi-organ lesions. Acute kidney injuryis a complicated multifocal syndrome manifested by aclinical decrease of the diuresis rate and characterized bya rapid increase of creatinine concentration in laboratoryconditions. High serum creatinine level is not a specificsign of kidney injury, its level changes much later thanglomerular filtration rate, and depends on many nonrenal factors. Furosemide is the only direct diuretic inchildren, but its use is limited in this pathology. Thereare no recommendations on the frequency and duration offurosemide administration.Conclusions: The study of new diagnostic markersand possibilities of using drugs that increase glomerularfiltration in the kidneys in comparison with furosemide, andpreventing the progression of their damage, determiningthe minimal preventive dose, terms and frequency ofadministration, the study of early and late consequences,side effects of this therapy, is a promising direction ofscientific search.


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