scholarly journals Cerebrospinal Fluid Alzheimer’s Disease Biomarkers Across the Spectrum of Lewy Body Diseases: Results from a Large Multicenter Cohort

2016 ◽  
Vol 54 (1) ◽  
pp. 287-295 ◽  
Author(s):  
Inger van Steenoven ◽  
Dag Aarsland ◽  
Daniel Weintraub ◽  
Elisabet Londos ◽  
Frédéric Blanc ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Lewy Body ◽  
Disease Biomarkers ◽  
Multicenter Cohort ◽  
Lewy Body Diseases

scholarly journals Cerebrospinal Fluid Levels of sAPPαand sAPPβin Lewy Body and Alzheimer's Disease: Clinical and Neurochemical Correlates

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Ezra Mulugeta ◽  
Elisabet Londos ◽  
Oskar Hansson ◽  
Clive Ballard ◽  
Ragnhild Skogseth ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Lewy Body ◽  
Group Analysis ◽  
Lewy Body Dementia ◽  
Csf Biomarkers ◽  
Commercial Kits ◽  
Neurochemical Correlates ◽  
Fluid Levels

We measured cerebrospinal fluid (CSF) levels of the soluble isoforms of amyloid precursor protein (APP; sAPPαsAPPβ) and other CSF biomarkers in 107 patients with Alzheimer's disease (AD), dementia with Lewy body dementia (DLB), Parkinson's disease dementia (PDD), and normal controls (NC) using commercial kits. DLB and PDD were combined in a Lewy body dementia group (LBD). No differences were observed in sAPPαand sAPPβlevels between the groups. Significant correlations were observed between sAPPαand sAPPβand between sAPPβand Mini-Mental State Examination scores in the total group analysis as well as when LBD and AD groups were analyzed separately. sAPPαand sAPPβlevels correlated with Aβ38, Aβ40, Aβ42, and Tau in the LBD group. In AD, sAPPαcorrelated with p-Tau and sAPPβwith Aβ40. The differential association between sAPPαand sAPPβwith Aβand Tau species between LBD and AD groups suggests a possible relationship with the underlying pathologies in LBD and AD.

scholarly journals Development of a robust and stable mass based spectrometry method for analysis of Alzheimer’s disease biomarkers in human cerebrospinal fluid

2020 ◽  
Vol 16 (S5) ◽  
Author(s):  
Shannon N. Leslie ◽  
Rashaun Wilson ◽  
Bianca A. Trombetta ◽  
Pia Kivisäkk ◽  
Steven E. Arnold ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Spectrometry Method ◽  
Disease Biomarkers ◽  
Human Cerebrospinal Fluid

scholarly journals Relationships of Cerebrospinal Fluid Alzheimer’s Disease Biomarkers and COMT, DBH, and MAOB Single Nucleotide Polymorphisms

2020 ◽  
Vol 73 (1) ◽  
pp. 135-145
Author(s):  
Mirjana Babić Leko ◽  
Matea Nikolac Perković ◽  
Nataša Klepac ◽  
Dubravka Švob Štrac ◽  
Fran Borovečki ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Disease Biomarkers

Cerebrospinal Fluid Alzheimer’s Disease Biomarkers in Isolated Supratentorial Cortical Superficial Siderosis

2016 ◽  
Vol 54 (4) ◽  
pp. 1291-1295 ◽  
Author(s):  
Dimitri Renard ◽  
Audrey Gabelle ◽  
Christophe Hirtz ◽  
Christophe Demattei ◽  
Eric Thouvenot ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Superficial Siderosis ◽  
Disease Biomarkers ◽  
Cortical Superficial Siderosis

scholarly journals Hippocampal subfield pathologic burden in Lewy body diseases vs . Alzheimer’s disease

2020 ◽  
Vol 46 (7) ◽  
pp. 707-721
Author(s):  
D. G. Coughlin ◽  
R. Ittyerah ◽  
C. Peterson ◽  
J. S. Phillips ◽  
S. Miller ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Lewy Body ◽  
Lewy Body Diseases

Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid

2006 ◽  
Vol 10 (4) ◽  
pp. 399-406 ◽  
Author(s):  
Robert G. Riekse ◽  
Ge Li ◽  
Eric C. Petrie ◽  
James B. Leverenz ◽  
Darcy Vavrek ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Disease Biomarkers
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