Destination Memory and Cognitive Theory of Mind in Alzheimer’s Disease

2015 ◽  
Vol 48 (2) ◽  
pp. 529-536 ◽  
Author(s):  
Mohamad El Haj ◽  
Marie-Christine Gély-Nargeot ◽  
Stéphane Raffard
2019 ◽  
Vol 34 (8) ◽  
pp. 1409-1417 ◽  
Author(s):  
Mohamad El Haj ◽  
Philippe Allain ◽  
Ahmed A Moustafa

AbstractObjectiveTheory of mind and destination memory are social abilities that require processing the attributes of interlocutors. Empirical research has demonstrated a relationship between performance on both abilities in normal aging and Alzheimer’s disease (AD). We therefore investigated whether processing attributes of interlocutors would result in better destination memory in AD.MethodsTwenty-six mild AD participants and 28 controls were tested on two occasions. On the first one, participants had to tell proverbs to celebrities’ faces. Following that, they decided whether they previously told that proverb to that celebrity or not. The same procedures were repeated on the second occasion; however, after telling the proverbs, participants had to introspect about what the celebrities might think about the proverbs (e.g., “what do you think that the celebrities would think about the proverbs?”).ResultsGroup comparisons showed a beneficial effect of introspection on destination memory in controls (Z = −2.57, p < .05) but not in AD participants (Z = −1.05, p = .29). However, analyzes of individual profiles demonstrated that 15 AD participants demonstrated better destination memory after introspection.ConclusionsOur findings show a beneficial effect of introspection on destination memory in normal aging, and at least in some mild AD cases. Future research should investigate the influence of social cognition on memory in AD and how introspection may provide a potential treatment for AD.


2016 ◽  
Vol 27 (4) ◽  
pp. 257-264 ◽  
Author(s):  
Johannes H. Scheidemann ◽  
Franz Petermann ◽  
Marc Schipper

Abstract. We investigated theory of mind (ToM) deficits in Alzheimer‘s disease (AD) and its possible connection to autobiographical memory (ABM). Patients and matched controls were evaluated and compared using a video-based ToM test, an autobiographical fluency task, and a neuropsychological test battery. We found that ToM deficits were positively associated with semantic ABM in the clinical group, whereas a positive relationship appeared between ToM and episodic ABM in controls. We hypothesize that this reflects the course of the disease as well as that semantic ABM is used for ToM processing, being still accessible in AD. Furthermore, we assume that it is also less efficient, which in turn leads to a specific deficit profile of social cognition.


Cortex ◽  
2013 ◽  
Vol 49 (1) ◽  
pp. 82-89 ◽  
Author(s):  
Mohamad El Haj ◽  
Virginie Postal ◽  
Philippe Allain

2020 ◽  
Vol 26 (10) ◽  
pp. 963-977
Author(s):  
Olivia P. Demichelis ◽  
Sarah P. Coundouris ◽  
Sarah A. Grainger ◽  
Julie D. Henry

AbstractObjective:A large literature now shows that Alzheimer’s disease (AD) disrupts a number of social cognitive abilities, including social perceptual function and theory of mind (ToM). However, less well understood is how the specific subcomponents of ToM as well as both the broader and specific subcomponents of empathic processing are affected.Method:The current study provides the first meta-analytic review of AD that focuses on both empathy and ToM as broad constructs, as well as their overlapping (cognitive empathy and affective ToM) and distinct (affective empathy and cognitive ToM) subcomponents.Results:Aggregated across 31 studies, the results revealed that, relative to controls, AD is associated with large-sized deficits in both cognitive ToM (g = 1.09) and affective ToM/cognitive empathy (g = 0.76). However, no statistical differences were found between the AD participants and controls on affective empathic abilities (g = 0.36).Conclusions:These data point to a potentially important disconnect between core aspects of social cognitive processing in people with AD. The practical and theoretical implications of these findings are discussed.


2020 ◽  
Vol 14 (3) ◽  
pp. 399-415 ◽  
Author(s):  
Elif Yildirim ◽  
Ezgi Soncu Buyukiscan ◽  
Aslı Demirtas‐Tatlidede ◽  
Başar Bilgiç ◽  
Hakan Gurvit

2013 ◽  
Vol 26 (3) ◽  
pp. 215-216 ◽  
Author(s):  
Mohamad El Haj ◽  
Virginie Postal ◽  
Didier Le Gall ◽  
Philippe Allain

2015 ◽  
Vol 12 (8) ◽  
pp. 796-801 ◽  
Author(s):  
Mohamad El Haj ◽  
Stephane Raffard ◽  
Pascal Antoine ◽  
Marie-Christine Gely-Nargeot

2020 ◽  
Vol 42 (3) ◽  
pp. 223-239
Author(s):  
Aline Tavares De Lucena ◽  
Rishi K. Bhalla ◽  
Tatiana Teresa Belfort Almeida Dos Santos ◽  
Marcia Cristina Nascimento Dourado

2020 ◽  
Vol 41 (5) ◽  
pp. 1027-1039 ◽  
Author(s):  
ZhongQuan Yi ◽  
PanWen Zhao ◽  
Hui Zhang ◽  
YuanYuan Shi ◽  
HaiChun Shi ◽  
...  

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