Quantitative parameters of contrast-enhanced ultrasonography for assessment of renal pathology: A preliminary study in chronic kidney disease

2018 ◽  
Vol 68 (1) ◽  
pp. 71-82 ◽  
Author(s):  
Wen-qi Yang ◽  
Shan Mou ◽  
Yao Xu ◽  
Li Xu ◽  
Feng-hua Li ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Pathology ◽  
Quantitative Parameters ◽  
Contrast Enhanced ◽  
Contrast Enhanced Ultrasonography ◽  
Preliminary Study

scholarly journals Preliminary Study of the Effects of Eccentric-Overload Resistance Exercise on Physical Function and Torque Capacity in Chronic Kidney Disease

2020 ◽  
Vol 5 (4) ◽  
pp. 97
Author(s):  
Jared M. Gollie ◽  
Samir S. Patel ◽  
Joel D. Scholten ◽  
Michael O. Harris-Love
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Resistance Exercise ◽  
Physical Function ◽  
Future Research ◽  
Timed Up And Go ◽  
Isokinetic Test ◽  
Torque Capacity ◽  
Preliminary Study ◽  
Eccentric Overload

The purpose of this preliminary study was to describe changes in physical function and torque capacity in adults with chronic kidney disease (CKD) in response to a novel progressive eccentric-overload resistance exercise (ERE) regime. Participants included men (n = 4) diagnosed with CKD according to estimated glomerular filtration rate (eGFR) between 59 and 15 mL/kg/1.73 m2 and not requiring dialysis. Physical function was determined by the Short Physical Performance Battery (SPPB), five repetitions of a sit-to-stand (STS) task, and timed-up and go (TUG). Knee extensor strength was assessed using both isometric and isokinetic contractions and performance fatigability indexes were calculated during a 30-s maximal isometric test and a 30-contraction isokinetic test at 180°/second. None of the patients exhibited significant worsening in their health status after training. Participants demonstrated improvements in several measures of physical function and torque capacity following 24 sessions of ERE. Following training, performance fatigability remained relatively stable despite the increases in torque capacity, indicating the potential for greater fatigue resistance. These findings provide initial evidence for ERE as a potential treatment option to combat declines in physical function and neuromuscular impairments in people with CKD. Future research is required to determine optimal progression strategies for maximizing specific neuromuscular and functional outcomes when using ERE in this patient population.

A preliminary study of blood-oxygen-level-dependent MRI in patients with chronic kidney disease

2012 ◽  
Vol 30 (3) ◽  
pp. 330-335 ◽  
Author(s):  
Pei Xin-Long ◽  
Xie Jing-Xia ◽  
Liu Jian-Yu ◽  
Wang Song ◽  
Tian Xin-Kui
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level ◽  
Preliminary Study

scholarly journals Urine headspace analysis with field asymmetric ion mobility spectrometry for detection of chronic kidney disease

2020 ◽  
Vol 14 (8) ◽  
pp. 629-638
Author(s):  
Elina Jokiniitty ◽  
Lauri Hokkinen ◽  
Pekka Kumpulainen ◽  
Yrjö Leskinen ◽  
Terho Lehtimäki ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Function ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Headspace Analysis ◽  
Diagnostic Tools ◽  
Electronic Noses ◽  
Volatile Organic ◽  
Preliminary Study

Electronic noses (eNoses) are an emerging class of experimental diagnostic tools. They are based on the detection of volatile organic compounds. Urine is used as sample medium in several publications but neither the effect of chronic kidney disease (CKD) on the analysis nor the potential to detect CKD has been explored. Materials & methods: We utilized an eNose based on field asymmetric ion mobility spectrometry (FAIMS) technology to classify urine samples from CKD patients and controls. Results: We were able to differentiate extremes of kidney function with an accuracy of 81.4%. Conclusion: In this preliminary study, applying eNose technology we were able to distinguish the patients with impaired kidney function from those with normal kidney function.

Glucose Metabolism, Insulin Resistance, and Renal Pathology in Non-Diabetic Chronic Kidney Disease

2008 ◽  
Vol 108 (2) ◽  
pp. c163-c168 ◽  
Author(s):  
Ryota Ikee ◽  
Yoshifumi Hamasaki ◽  
Machiko Oka ◽  
Kyoko Maesato ◽  
Tsutomu Mano ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Chronic Kidney Disease ◽  
Glucose Metabolism ◽  
Kidney Disease ◽  
Renal Pathology

scholarly journals Hypertension, Chronic Kidney Disease, and Renal Pathology in a Child with Hermansky-Pudlak Syndrome

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Roberto Gordillo ◽  
Marcela Del Rio ◽  
David B. Thomas ◽  
Joseph T. Flynn ◽  
Robert P. Woroniecki
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Stage Ii ◽  
Renal Pathology ◽  
Disease Stage ◽  
Not Otherwise Specified ◽  
Ckd Stage ◽  
History Of ◽  
Hermansky Pudlak Syndrome

We report a child with Hermansky-Pudlak Syndrome (HPS) and chronic kidney disease (stage II) with histological diagnosis of focal segmental glomerulosclerosis (FSGS). A 15-year-old male of Puerto Rico ancestry with history of HPS, hypertension (HTN), asthma, obesity, and chronic kidney disease (CKD) stage II presented with new-onset proteinuria without edema. His blood pressure had been controlled, serum creatinine had been 0.9–1.4 mg/dL, and first morning urine protein/creatinine ratio (UPC) ranged from 0.2 to 0.38. Due to persistent nonorthostatic proteinuria with CKD, renal biopsy was performed and FSGS (not otherwise specified) with chronic diffuse tubulopathy (tubular cytoplasmic droplets) and acute tubular injury was reported. Ceroid-like material is known to infiltrate tissues (i.e., lungs, colon, and kidney) in HPS, but the reason for the renal insufficiency is unknown. Nonspecific kidney disease and in one adult case IgA nephropathy with ANCA-positive glomerulonephritis have previously been reported in patients with Hermansky-Pudlak syndrome. To our knowledge, we report the first pediatric renal pathology case of HPS associated with CKD. This paper discusses presentation and management of renal disease in HPS.

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