MiR-200c-3p suppression is associated with development of acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer via a mediating epithelial-to-mesenchymal transition (EMT) process

Hsin-Yi Wang; Yi-Nan Liu; Shang-Gin Wu; Chia-Lang Hsu; Tzu-Hua Chang; Meng-Feng Tsai; Yen-Ting Lin; Jin-Yuan Shih

doi:10.3233/cbm-191119

MiR-200c-3p suppression is associated with development of acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer via a mediating epithelial-to-mesenchymal transition (EMT) process

Cancer Biomarkers ◽

10.3233/cbm-191119 ◽

2020 ◽

Vol 28 (3) ◽

pp. 351-363

Author(s):

Hsin-Yi Wang ◽

Yi-Nan Liu ◽

Shang-Gin Wu ◽

Chia-Lang Hsu ◽

Tzu-Hua Chang ◽

...

Keyword(s):

Epithelial To Mesenchymal Transition ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Mesenchymal Transition ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant

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Epidermal growth factor receptor T790M mutation as a prognostic factor in EGFR-mutant non-small cell lung cancer patients that acquired resistance to EGFR tyrosine kinase inhibitors

Oncotarget ◽

10.18632/oncotarget.19681 ◽

2017 ◽

Vol 8 (59) ◽

pp. 99429-99437 ◽

Cited By ~ 6

Author(s):

Guangzhi Ma ◽

Jing Zhang ◽

Hai Jiang ◽

Nannan Zhang ◽

Liyuan Yin ◽

...

Keyword(s):

Kinase Inhibitors ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

T790m Mutation ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant

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Tumor heterogeneity affects the activity of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in EGFR mutant non-small cell lung cancer (NSCLC) patients (pts)

Annals of Oncology ◽

10.1093/annonc/mdw332.03 ◽

2016 ◽

Vol 27 ◽

pp. iv4

Author(s):

N. Normanno ◽

A.M. Rachiglio ◽

M. Lambiase ◽

F. Fenizia ◽

A. Iannaccone ◽

...

Keyword(s):

Lung Cancer ◽

Tumor Heterogeneity ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant ◽

Nsclc Patients

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Making progress in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer by surpassing resistance: third-generation EGFR tyrosine kinase inhibitors (EGFR-TKIs)

Annals of Translational Medicine ◽

10.21037/atm.2017.10.04 ◽

2018 ◽

Vol 6 (8) ◽

pp. 140-140 ◽

Cited By ~ 8

Author(s):

Giannis Mountzios

Keyword(s):

Lung Cancer ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Third Generation ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant ◽

Egfr Tkis

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Tumor heterogeneity affects the activity of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in EGFR mutant non-small cell lung cancer (NSCLC) patients (pts)

Annals of Oncology ◽

10.1093/annonc/mdw383.35 ◽

2016 ◽

Vol 27 ◽

pp. vi427

Author(s):

N. Normanno ◽

A.M. Rachiglio ◽

M. Lambiase ◽

F. Fenizia ◽

A. Iannaccone ◽

...

Keyword(s):

Lung Cancer ◽

Tumor Heterogeneity ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant ◽

Nsclc Patients

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The role of epithelial to mesenchymal transition in resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer

Translational Lung Cancer Research ◽

10.21037/tlcr.2016.04.07 ◽

2016 ◽

Vol 5 (2) ◽

pp. 172-182 ◽

Cited By ~ 36

Author(s):

Kristine Raaby Jakobsen ◽

Christina Demuth ◽

Boe Sandahl Sorensen ◽

Anders Lade Nielsen

Keyword(s):

Receptor Tyrosine Kinase ◽

Epithelial To Mesenchymal Transition ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Mesenchymal Transition ◽

Epidermal Growth ◽

Receptor Tyrosine Kinase Inhibitors

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467P Efficacy of cranial radiotherapy prior to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer patients with brain metastases

Annals of Oncology ◽

10.1093/annonc/mdv532.51 ◽

2015 ◽

Vol 26 ◽

pp. ix125

Author(s):

N. Tsushita ◽

Y. Goto ◽

H. Shiraishi ◽

K. Tsuruoka ◽

K. Yoshida ◽

...

Keyword(s):

Lung Cancer ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Cranial Radiotherapy ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant

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Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer: A new era begins

Cancer Treatment Reviews ◽

10.1016/j.ctrv.2013.06.002 ◽

2014 ◽

Vol 40 (1) ◽

pp. 93-101 ◽

Cited By ~ 76

Author(s):

J. Remon ◽

T. Morán ◽

M. Majem ◽

N. Reguart ◽

E. Dalmau ◽

...

Keyword(s):

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

New Era ◽

Epidermal Growth ◽

Egfr Mutant ◽

Receptor Tyrosine Kinase Inhibitors

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HER3 ligand heregulin expression and clinical implication in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer treated with EGFR-tyrosine kinase inhibitors

Annals of Oncology ◽

10.1093/annonc/mdz260.057 ◽

2019 ◽

Vol 30 ◽

pp. v630-v631

Author(s):

K. Yonesaka ◽

E. Iwama ◽

H. Hayashi ◽

S. Suzuki ◽

R. Kato ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant

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The quantitatively analysis of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) and its correlation with response rate of EGFR tyrosine kinase inhibitors (TKI)

10.1158/diag-10-pr10 ◽

2010 ◽

Cited By ~ 1

Author(s):

Jun Li ◽

Zhao Chen ◽

Daqiang Sun ◽

Meilin Xu ◽

Xun Zhang ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Kinase Inhibitors ◽

Response Rate ◽

Growth Factor Receptor ◽

Small Cell ◽

Egfr Mutations ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Expression of insulin-like growth factor 1 receptor (IGF-1R) predicts poor responses to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer patients harboring activating EGFR mutations

Lung Cancer ◽

10.1016/j.lungcan.2015.01.004 ◽

2015 ◽

Vol 87 (3) ◽

pp. 311-317 ◽

Cited By ~ 31

Author(s):

Chang Dong Yeo ◽

Ki Hoon Park ◽

Chan Kwon Park ◽

Sang Haak Lee ◽

Seung Joon Kim ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Egfr Mutations ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

Download Full-text